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Expected Outcome:This topic aims at supporting activities that are enabling or contributing to one or several expected impacts of destination “Tackling diseases and reducing disease burden”. To that end, proposals under this topic should aim to deliver results that are directed at, tailored towards and contributing to some of the following expected outcomes:Researchers, healthcare practitioners and providers in low- and middle-income countries (LMICs)[1] and/or those in high-income countries (HICs) serving disadvantaged populations have access to improved insights and evidence on how to equitably promote the early prevention, risk reduction, and timely diagnosis of Non-Communicable Diseases (NCDs) in children and/or young people.Policymakers, public health managers and authorities, parents and their children, and young adults have access to evidence and recommendations for national progr...

Expected Outcome:This topic aims at supporting activities that are enabling or contributing to one or several expected impacts of destination “Tackling diseases and reducing disease burden”. To that end, proposals under this topic should aim to deliver results that are directed at, tailored towards and contributing to all the following expected outcomes:The scientific and clinical communities have a better understanding of and access to new and innovative products for the treatment of antimicrobial resistant bacteria and fungi, as well as for further clinical investigation.Candidate therapies are available to treat patients for antimicrobial resistant bacteria and fungi, increasing therapeutic options for clinical deployment in the fight against Antimicrobial Resistance (AMR). Scope:The rapid rise of AMR presents a formidable threat to public health, challenging our ability to treat infe...

Expected Outcome:This topic aims at supporting activities that are enabling or contributing to one or several expected impacts of destination “Tackling diseases and reducing disease burden”. To that end, proposals under this topic should aim to deliver results that are directed at, tailored towards and contributing to all the following expected outcomes:The scientific and clinical communities have a better understanding of and access to experimental monoclonal antibodies for the prevention and treatment of emerging or re-emerging viral infections, as well as for further clinical investigation.Candidate monoclonal antibody therapies are available to treat patients for emerging and re-emerging viral infections, increasing therapeutic options for clinical deployment in case of an epidemic or pandemic. Scope:Infectious diseases remain a major threat to health and health security in the EU an...

Expected Outcome:This topic aims at supporting activities that are enabling or contributing to one or several expected impacts of destination “Tackling diseases and reducing disease burden”. To that end, proposals under this topic should aim to deliver results that are directed at, tailored towards and contributing to all the following expected outcomes:The scientific and clinical communities have a better understanding of and access to experimental monoclonal antibodies for the prevention and treatment of emerging or re-emerging viral infections, as well as for further clinical investigation.Candidate monoclonal antibody therapies are available to treat patients for emerging and re-emerging viral infections, increasing therapeutic options for clinical deployment in case of an epidemic or pandemic. Scope:Infectious diseases remain a major threat to health and health security in the EU an...

Expected Outcome:This topic aims at supporting activities that are enabling or contributing to one or several expected impacts of destination “Staying healthy in a rapidly changing society”. To that end, proposals under this topic should aim to deliver results that are directed at, tailored towards and contributing to all the following expected outcomes:Persons with disabilities are empowered and can enjoy their rights to live independently, participate in society and be included in the community on an equal basis with others.The scientific community develops innovative solutions with a focus on removing barriers faced by persons with disabilities to live independently and they are provided with community support services where they live in the community.Policymakers, health and care services, social and service providers, disability organisations, funders, the scientific community, and...

Expected Outcome:This topic aims at supporting activities that are enabling or contributing to one or several expected impacts of destination “Tackling diseases and reducing disease burden”. To that end, proposals under this topic should aim to deliver results that are directed at, tailored towards and contributing to all the following expected outcomes:The scientific and clinical communities have a better understanding of and access to experimental antivirals for the prevention and treatment of emerging or re-emerging viral infections, as well as for further clinical investigation.Candidate antiviral therapies are available to treat patients for emerging and re-emerging viral infections, increasing therapeutic options for clinical deployment in case of an epidemic or pandemic. Scope:Infectious diseases remain a major threat to health and health security in the EU and globally. Viral dis...

Expected Outcome:This topic aims at supporting activities that are enabling or contributing to one or several expected impacts of destination “Living and working in a health-promoting environment”. To that end, proposals under this topic should aim to deliver results that are directed at, tailored towards and contributing to most of the following expected outcomes:Researchers, policymakers, healthcare practitioners and the public have a more comprehensive understanding of the human exposome and the interactions between climatic, environmental and socio-behavioural factors, supported by FAIR[1] data linking these exposures to disease and health outcomes.Researchers, governments, policymakers, social care services and healthcare practitioners have improved knowledge on the links between the climatic, social, lifestyle and environmental factors of the exposome and global health burden, supp...

Expected Outcome:This topic aims at supporting activities that are enabling or contributing to one or several expected impacts of destination “Maintaining an innovative, sustainable, and competitive EU health industry”. To that end, proposals under this topic should aim to deliver results that are directed at, tailored towards and contributing to all the following expected outcomes:Biopharmaceutical industries get access to streamlined development and production processes for peptide- or protein-based biologicals.Health systems benefit from the availability of enhanced or decentralised production systems for innovative health technologies that involve peptides or proteins, and which improve health and care.Citizens and patients will benefit from better access, availability and affordability of pharmaceuticals based on biologicals. Scope:Cell-Free Protein Synthesis (CFPS) has been employe...

Expected Outcome:This topic aims at supporting activities that are enabling or contributing to one or several expected impacts of destination “Ensuring equal access to innovative, sustainable, and high-quality healthcare”. To that end, proposals under this topic should aim to deliver results that are directed at, tailored towards and contributing to all the following expected outcomes:Patients benefit from decreased incidence of Adverse Drug Reactions (ADRs) caused by the administration of multiple medications (three or more medicinal products[1]) and enhanced health outcomes by ensuring safer and more effective use of medication.Healthcare professionals can adopt adverse drug reactions prevention and reduction strategies to integrate genetic and other biomarker information into clinical decision-making to optimise the use of medication, especially in situations of comorbidities.Healthca...

The Established Program to Stimulate Competitive Research is designed to fulfill the mandate of the National Science Foundation (NSF) to promote scientific progress nationwide. NSF EPSCoR facilitates the establishment of partnerships among academic institutions, government, industry, and non-profit sectors that are designed to promote sustainable improvements in a jurisdiction's research infrastructure, Research and Development (R&D) capacity, and R&D competitiveness of EPSCoR-eligible jurisdictions (i.e., states, territories, and commonwealths). Eligibility to participate in the EPSCoR funding opportunities, including the EPSCoR RII: EPSCoR Research Fellows program, is described on theNSF EPSCoR website. EPSCoR RII: EPSCoR Research Fellows directly aligns with the NSF EPSCoR strategic goal of establishing sustainable Science, Technology, Engineering, and Mathematics (STEM) professional development pathways that advance workforce development and effects engagement in STEM at national and global levels. EPSCoR RII: EPSCoR Research Fellows provides awards to build researchcapacityin institutions and transform the career trajectories of investigators and further develop their individual research potential through collaborations with investigators from the nation’s premier private, governmental, or academic research institutions and/or centers. The fellowship provides opportunities to establish strong collaborations through extended or periodic collaborative visits to a selected host site.Through collaborative research activities with the host site, Fellows will be able to lear...

Expected Outcome:Project outputs and results are expected to contribute to all the following expected outcomes: Demonstrate autonomy, of at least 150 nm (or 277.8 KM for inland navigation) using electrical storage as the only energy source, while allowing rapid in-route zero-emission replenishment. Increase the power output, providing beyond 5 MW as peak propulsion power with corresponding grid capacity. Improve systems to increase the number charging cycles combined with high-power charging to suit the operation needs of different ship types and services. Identify the operating profiles and business cases for which electric powered shipping will bring significant improvements taking into account the priorities and provisions of the Fitfor55 package, especially FuelEU Maritime, Naiades III, AFIR and RED. Develop solutions fitting different ship types and their operational profiles and pr...

Expected Outcome:Project results are expected to contribute to all of the following expected outcomes.Improved water resilience and good environmental and good ecological status in European waters and contribute to the achievement of the European Union's environmental targets, including the European Water Resilience Strategy and the European Ocean Pact. A comprehensive understanding of the future environmental impacts of waterborne transport on marine and other aquatic ecosystems, addressing in particular pollution sources from: i) navigation on renewable low and zero-carbon fuels; and ii) accidental spills of renewable low and zero-carbon fuels for marine waters, inland waters and ports (water and air quality).Innovative prevention, abatement and mitigation systems and strategies for reducing and eliminating the harmful impacts of waterborne transport on waters.Enhanced pollution preven...

Expected Outcome:Project results are expected to contribute to all of the following expected outcomes:Standardised fire risk assessment for EVs’[1] fire hazards in constrained spaces and areas such as underground/ built-in parking lots, garages, ferryboats and depots with and without charging facilities and during mono- or bidirectional charging.Innovative on-board and/or off-board affordable fire-detection, suppression, and containment measures and techniques.Standardised fire protocols and open evaluation frameworks.Enhanced public perception of fire safety across all EV categories. Scope:The overall fire safety risks associated with Electric Vehicles (EVs) are substantially lower compared to those of Internal Combustion Engine (ICE) vehicles. However, public concerns and perceptions about EV fire safety may still persist. This necessitates a thorough examination and addressing of pote...

Expected Outcome:Project results are expected to contribute to all of the following expected outcomes:Demonstrated integration potential and modularity of next level advanced high-voltage systems to benefit cost of Commercial Vehicles (CV) in particular for the Heavy-Duty Vehicles (HDV) segment.Improved energy efficiency and higher utilization potential of HDV (ensuring full operational capability for the intended usage models) via high-voltage powertrain configurations.Demonstrated benefits of high-voltage systems also for fast charging and auxiliary components. Scope:Major challenges still faced by Heavy Duty Battery Electric Vehicles (HD-BEV) are cost and fast charging. As electric vehicles become more attractive through Total Cost of Ownership (TCO), significantly higher acquisition costs remain, partly caused by the wide spectrum of usage scenarios and a relatively low number of veh...

Expected Outcome:Project results are expected to contribute to all of the following expected outcomes:Integration of the results of the demonstrations in regular operation of passenger transport operators, in long distance operations. Accelerated replication of this integration, beyond original demo partners, using specific recommendations and sharing of best practicesReliable operation of long distance zero emission buses and coaches in the EU.Improved comfort and inter-modality for long distance people mobility services.Demonstrated innovative zero emission solutions for long distance people mobility in a holistic approach taking net congestions challenges and charging solutions into account. Scope:Zero emission buses for urban and sub-urban use are successfully implemented in Europe. This has addressed the need to improve air quality, reduce noise and innovate people mobility. Yet the...

Expected Outcome:Expected outcomes area A) Circular economy for Electric Vehicle (EV) powertrains and infrastructure:Project results are expected to contribute to all the following outcomes:Minimized cradle to grave/cradle environmental impact of EV drivetrains (excluding batteries at cell level) and Electric Vehicle Charging Infrastructure (EVCI), especially electro-mechanical components and power-electronics, via design strategies for extended lifetime and reduced usage of CRM, and other materials, particularly those that may hamper high quality recycling (e.g. harmful substances), while ensuring high performance and market acceptability.Improved repair, recovery, refurbish and re-use of end-of-first-life drivetrain components and EVCI through accurate and standardised assessment of the health and Remaining Useful Life (RUL), which should inform better design strategies and potential b...

Expected Outcome:Project results are expected to contribute to both of the following expected outcomes:Additive manufacturing including high performance polymers, composites and metals, offering significantly improved performance compared to state-of-the-art. Entire process including design / manufacturing / characterization and testing / certification.Sustainable aircraft circular design and manufacturing processes of individual high-value components towards further developing the innovation pipeline from system demonstration to deployment stage in the EU and Associated Countries. Scope:This topic focuses on:Additive design and manufacturing of aircraft and engine structural components have already transformed the industry and are expected to be the key to the EU competitiveness. Geopolitical aspects for raw materials reinforce the importance of additive manufacturing, while the Europea...

Expected Outcome:Project results are expected to contribute to all of the following expected outcomes:Assessment of the impact of airport operations on air quality and water bodies (including biodiversity) through air quality measurements and monitoring at different spots in and around the airports as well as through in vitro testing and/or remote sensing for water quality in airports close to water bodiesContributing to the delivery of better emission factors for emissions inventories and projections (including EMEP), especially for species and fuel mixtures for which little knowledge exists today in order to support local, regional, national and international emissions reduction plans (e.g. Noise Plans, Air Quality Roadmaps, Air Quality Plans, national Air Pollution Control Programmes, as mentioned in EU acquis) by providing real-world emission information and measuring the actual impa...

Expected Outcome:Project results are expected to contribute to all the following expected outcomes: Drafting of a R&I roadmap towards deploying nuclear power in commercial shipping, including small modular reactors (SMRs) and other advanced nuclear technologies (e.g. complementing the latest European Industrial Alliance on SMRs technology roadmap[1]), including identification of research gaps, infrastructures and future innovation needsMapping of relevant regulatory regimes nationally, regionally and internationally for the use of nuclear-powered shipping, including recommendations on regulatory frameworks and international cooperation.Development of scenarios for the use of the technology, including potential damage scenarios.The implications for National Energy and Climate Plans and National Air Pollution Control Programmes as well as water pollution policies required by EU legislative...

Expected Outcome:Project outputs and results are expected to contribute to all the following expected outcomes: Demonstration of remote-control operation of vessels without crew, controlled remotely (degree three[1]). Development of concepts for fully autonomous ship where the operating system on the vessel is able to make decisions and determine actions by itself (degree four[2]). Strengthen market confidence in the integration of remote and automated navigation in ship types and services that may see a shortage of workforce in the next decade.Contribute to the EU Port Strategy and the EU Industrial Waterborne Strategy, as well as the EU AI Continent Action Plan[3] and the upcoming EU Apply AI Strategy. Scope:Maritime Autonomous Surface Ships (MASS) have been the focus for several projects both with EU-funding and individual countries but a major breakthrough leading to extensive deploy...

The FAIROS Program seeks to support a broad range of transformative open science activities including but not limited to i.) Research, education, and socio-technical cyberinfrastructure development capacities that advance sustainable multi-disciplinary findable, accessible, interoperable, reusable (FAIR) research data management (RDM) and open science capabilities, ii.) Piloting new models of scientific communication and publication that improve efficiency and accessibility, iii.) Developing FAIROS data portals, research data commons, RDM as a national service, and iv.) Lowering barriers to accessing, curating, integrating, linking, managing, sharing, and storing data across many disciplinary domains, irrespective of data size. The program supports innovation across the cyberinfrastructure (CI) ecosystem to address accessibility, data curation, research data management, discoverability, reliability, reproducibility, preservation, sustainability, and utility of research products, including data software, and code, developed as part of funded projects. FAIROS proposals must select one of two tracks to focus on, either: 1) Disciplinary Improvements to targeted scientific communities, or 2) Cross-Cutting Improvements that apply to many or most scientific disciplines. In the case of proposals focused on Disciplinary Improvements, it is strongly recommended that prospective PIs contact a program officer from the list of Cognizant Program Officers in the directorate closest to the major disciplinary impact of the proposed work to ascertain that the scientific focus and budget of t...

Expected Outcome:Project’s results are expected to contribute to the following expected outcomes: Full-scale demonstration of the combined solutions aiming to reduce ship GHG intensity and energy savings by at least 55%, compared to 2008 levels. Development of a standardized framework to verify improvements stemming from energy efficiency measures and standardized interfacing with certification of renewable energy solutions to strengthen the implementation of FuelEU Maritime. Explore and establish assessment criteria, and sea-trial procedures for the combination of solutions. Adapt digital solutions towards standardised interface layers (hardware and software) to introduce data-driven optimisation and seamless integration.Facilitate the retrofitting of existing vessels with zero emission energy sources in combination with energy efficiency measures up to 2030. Address the safety and oper...

Expected Outcome:Project results are expected to contribute to the following outcomes:For staff membersIncreased set of research and transferable skills and competences, leading to improved employability and career prospects within and outside academia;More knowledge and innovative ideas converted into products, processes and services;More entrepreneurial mind-sets, testing new and innovative ideas;Increased international exposure leading to extended networks and opportunities;Enhanced networking and communication capacities with scientific peers, as well as with the general public that will increase and broaden the research and innovation impact. For participating organisationsInnovative ways of cooperation and transfer of knowledge between sectors and disciplines;Strengthened and broader international, inter-sectoral and interdisciplinary collaborative networks;Boosted R&I capacity. Sc...

NLM wishes to accelerate access to, and availability of, secure, complete datasets and computational models that can serve as the basis for transformative biomedical discoveries. Innovative at-scale computational approaches that increase the speed and scope of curation processes are needed for data mining and knowledge discovery from growing quantities of biomedical data being produced from ongoing data science advances.

The National Institutes of Health (NIH) hereby notify the applicant community that funds may be available for applications based on a presidentially declared disaster under the Stafford Act, a public health emergency declared by the Secretary, HHS, or other local, regional or national disaster. Applications in response to Emergency Notices of Special Interest (NOSIs) will be routed directly to the NIH awarding component signed on to the Emergency NOSI. Only applications submitted in response to an Emergency NOSI published by an IC will be allowed to apply to this NOFO.