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Expected Outcome:Project results are expected to contribute to the following outcomes:Increasing the market footprint of European startups in strategic digital technologies and deep tech[1] innovation, including but not limited to Artificial Intelligence, Advanced Computing, Cybersecurity, Next Generation Internet, Blockchain, Internet of Things, Metaverse, Energy, Greentech, AgriTech, and Fintech;Better connection of startups and scaleups, including European Institute of Innovation and Technology (EIT) and European Innovation Council (EIC)-supported startups and Seal of Excellence holders, to relevant local and/or European ecosystems, communities, and potential new markets;A scaling up of capabilities in matching technology solutions developed by highly innovative European Union (EU)-funded digital and deep tech startups with investment and growth opportunities in collaboration with oth...

Expected Outcome:Project results are expected to contribute to all of the following expected outcomes:increased circularity and reduced emissions of greenhouse gases and air pollutants in the economic sectors, services and product value chains at local and/or regional scale. This also includes an efficient valorisation of local resources, with positive effects on air and water quality as well as on biodiversity;widespread deployment and easier replication, scalability and visibility of circular systemic solutions for a multiplication of their economic, social and environmental benefits;enhanced collaboration and knowledge transfer between public authorities (cities and regions), companies, research and citizens in addressing environmental challenges, such as climate-change, resource depletion and biodiversity loss. Scope:This topic supports the implementation of the European Commission’s...

Expected Outcome:Project results are expected to contribute to all of the following expected outcomes:urban manufacturers significantly increase their resource efficiency through increased circular material use or reduced overall material use per output;urban manufacturers contribute significantly to EU climate, zero pollution, circularity and biodiversity goals by engaging in clean, sustainable and circular business practices;improved knowledge sharing and proliferation of digital tools and methods that facilitate the adoption of circular business practices and enable large-scale diffusion. Scope:The Clean Industrial Deal confirms Europe’s dedication to its decarbonisation goals by offering clear business incentives. It will help create lead markets to boost supply and demand in clean tech and energy-intensive industries (such as chemicals, cement, steel and metals), enabling the decarb...

Expected Outcome:This topic aims at directly engaging and supporting harbour/ports and their communities in demonstrating and accelerating the transitions needed for achieving one or several objectives of the Mission “Restore our Ocean and Waters”. The participation of relevant public bodies managing port authorities and their communities as partners of the consortium is strongly encouraged.Project results are expected to contribute to all of the following expected outcomes:Measurable, quantifiable, verifiable and ambitious progress towards reaching one or several interlinked objectives and targets of the Mission “Restore our Ocean and Waters by 2030”, as set out in the Mission Implementation Plan[1] through implementation of effective and well-managed place-based and people-centred actions;Involvement and increased readiness port cities and authorities for testing, deploying and upscali...

Expected Outcome:Activities under this topic will directly progress towards the goal of the Mission Soil to set up 100 living labs and lighthouses to lead the transition to healthy soils by 2030. Activities will also contribute to the goal of the Cancer Mission, i.e.: ‘to improve the lives of more than 3 million people by 2030, through prevention, cure and for those affected by cancer including their families, to live longer and better’. Activities should also contribute to meeting the European Green Deal ambitions and targets and more specifically those of the EU Biodiversity Strategy for 2030, the EU Soil Strategy for 2030, the proposal for a Soil Monitoring and Resilience Directive, the Zero Pollution Action Plan, the Europe's Beating Cancer Plan, the One Health approach, the European Health Data Space, the Chemicals Strategy for Sustainability, the European Chemicals Industry Action...

Expected Outcome:AI has the potential to support or facilitate virtually every aspect of regions’ climate adaptation efforts. From risk assessment to climate forecasting, from infrastructure planning to resource management, and more. Contributing to the objectives of the AI Continent Action Plan and the EU Mission on Adaptation to Climate Change, projects are expected to contribute one of the following:AI is used to improve actionable climate adaptation knowledge for European regions and local authorities by integrating climate data into decision-making processes.Specific sectors in the selected regions become more resilient to climate change thanks to the use of AI to improve their processes or technologies, while simultaneously advancing their digital transformation. Scope:RationaleOver the past few years, a rapid and disruptive acceleration of progress in Artificial Intelligence has o...

Expected Outcome:This topic aims at directly engaging with and supporting riparian and coastal areas, waterfront cities and islands and their communities in demonstrating and accelerating the transitions needed for achieving one or several objectives of the Mission “Restore our Ocean and Waters”. The participation of relevant public bodies managing those areas and their communities as partners of the consortium is strongly encouraged.Project results are expected to contribute to all the following outcomes:Member States and Associated Countries are provided with cost-effective and innovative solutions to increasing riparian and coastal areas’ resilience to climate change, especially in waterfront cities and islands, contributing to reach the targets of the EU climate adaptation and water resilience strategies for 2030, but also supporting achievements of the EU biodiversity strategy for 2...

Expected Outcome:Project results are expected to contribute to all of the following expected outcomes:Innovative business models for the development of entrepreneurship and successful local community-driven marine, coastal and freshwater sustainable tourism initiatives;Scalable and economically viable initiatives with the potential to be replicated across multiple sea basins;Enhanced capacity-building and increased engagement of the coastal/river/lake communities and the private sector;Job creation and skills development;Improved marine, coastal and freshwater habitats, biodiversity and enhanced conservation capacity;Increased awareness and behavioural change of tourists and coastal communities towards the conservation of marine and freshwater ecosystems. Scope:The community-driven approach under this topic puts strong emphasis on engaging coastal, riparian and/or lakeside communities as...

Expected Outcome:Proposals under this topic should aim to deliver results that are directed and tailored towards, and contribute to all of the following expected outcomes:Patients afflicted by lung, bowel, breast or prostate cancer[1], will benefit from the outcomes of evidence-based, tailored, innovative, affordable and accessible diagnosis- and treatment-centred clinical research programmes by comprehensive cancer infrastructures[2].Researchers, physicians, patient representatives, civil society, charities, foundations, insurance companies, SMEs and innovators[3] will seize opportunities to respectively co-create, support, upscale or commercialise outcomes of evidence-based, tailored, affordable and accessible clinical research programmes for the diagnosis and treatment of patients afflicted by lung, bowel, breast or prostate cancer.National and regional healthcare providers, healthcar...

Expected Outcome:This action supports the follow-up to the July 2023 Communication on EU Missions assessment[1]. The successful proposal under this topic should aim to deliver results that are directed and tailored towards and contribute to all of the following expected outcomes:Together, a network of registered cancer charities and funding agencies support transnational research and innovation projects on quality of life of children (age range 0-14, age at time of first diagnosis), adolescents (age range 15-19, age at time of first diagnosis) and young adults (age range 20-39, age at time of first diagnosis), cancer patients and survivors using their own financial resources.Projects supported by the network of charities and funding agencies will boost quality of life and long-term outcomes for young cancer patients and survivors, including improved physical, emotional, and social well-b...

Expected Outcome:Proposals under this topic should aim to deliver results that are directed and tailored towards, and contribute to all of the following expected outcomes:People at risk of cancer, cancer patients and their caregivers/families benefit from access to more effective and cost-effective, national or regional, cancer control programmes across EU Member States and Associated Countries.Researchers, physicians, innovators[1], SMEs and other professionals from different disciplines and sectors have access to national, regional or local data on healthcare spending (such as expenditures, resource allocations, organisation and type of healthcare interventions, and for which cancer indications, infrastructure, medical prescriptions, drug pricing, drug sales, reimbursement data from health insurers, population-based cancer registries or other cancer-centred registry data, longitudinal...

Expected Outcome:Project results are expected to contribute to all of the following expected outcomes:Increased area and improved condition of marine and coastal vegetated habitats within EU waters through effective on-site conservation, restoration and management of activities to help deliver on the objectives of the Nature Restoration Regulation;Maintained and enhanced capacity of blue carbon ecosystems to naturally store carbon, supporting EU climate mitigation goals;Enhanced capacity of marine vegetated habitats/blue carbon ecosystems to support biodiversity and fisheries;Established novel financing and incentive mechanisms that support conservation, restoration and management of blue forest ecosystems projects;Raised public awareness and improved community participation in blue forest ecosystems protection, restoration and management activities, ensuring long-term involvement. Scope...

Expected Outcome:In support to the implementation of the EU Adaptation Strategy, the EU Mission on Adaptation to Climate Change and the EU Preparedness Union Strategy and contributing to the upcoming European Climate Action Plan, project results are expected to improve adaptative capacities of European internal border regional and local authorities, allowing them to jointly address with their neighbours the pressing climate risks.Projects results should contribute to all of the following outcomes:Climate resilience solutions for cross-border risks have been developed and demonstrated. This includes social, governance or nature-based solutions.Regional and local authorities from each side of country borders are better prepared to withstand jointly the impacts of climate change, including systemic risks and cascading effects.National, regional and local authorities are taking on shared res...

Expected Outcome:Proposals under this topic should aim to deliver results that are directed and tailored towards, and contribute to all of the following expected outcomes:Patients with rare or very rare cancers or cancer subtypes have access to tailored, promising biomarker-guided medicines or multi-modal treatment interventions via participation in subsequent clinical trials or national or regional compassionate use programmes by health authorities;Researchers, physicians, innovators[1], startup, spin-off and spin-out companies, SMEs, charities or foundations and other professionals from different disciplines and sectors have access to innovative technology, medical devices or promising biomarker-guided medicines for further validation or commercialisation;National healthcare providers, policymakers and authorities in European regions, EU Member States and Associated Countries have earl...

Expected Outcome:Project results are expected to contribute to all of the following expected outcomes:Measurable improvements in the competitiveness and increased environmental sustainability of the EU’s fisheries and/or aquaculture sectors by integrating circular economy principles;Minimized and better managed waste products derived from fisheries and/or aquaculture sectors as well as improved reutilization and reduction of by-products;Reduced existing barriers preventing the implementation and development of circular principles in seafood chains, such as the cost of advanced processing technologies, regulatory hurdles, lack of collaboration across the different seafood supply chain actors or limited market demand and acceptance;Measurable socio-economic benefits for local stakeholders and communities involved in the seafood processing chain. Scope:Proposals under this topic are expecte...

Expected Outcome:Proposals under this topic should aim to deliver results that are directed and tailored towards and contribute to all of the following expected outcomes:Researchers and health professionals gain a deeper understanding of the functional effects of tumour heterogeneity during cancer initiation and progression, supporting the identification of more precise and novel therapeutic targets. Researchers, health professionals and innovators benefit from improved knowledge and tools to support the discovery and development of next generation genomically-informed cancer treatments.Researchers, innovators, and professionals across disciplines and sectors contribute to the UNCAN.eu research data platform by ensuring data interoperability, and enabling sustainable access to newly developed digital tools and models for the analysis and management of multimodal clinical data. Scope:The...

Expected Outcome:This topic aims at supporting activities that are enabling or contributing to one or several expected impacts of destination “Developing and using new tools, technologies and digital solutions for a healthy society”. To that end, proposals under this topic should aim to deliver results that are directed at, tailored towards and contributing to all the following expected outcomes:Clinical researchers and developers have access to novel predictive biomarkers to guide a more accurate assessment of disease progression and treatment response and tackle the unmet clinical needs of non-communicable chronic diseases.Clinicians and healthcare professionals use clinically validated predictive biomarkers for implementing more effective clinical research and personalised medicine with better health outcomes in chronic non-communicable diseases.Key stakeholders have access to trustwo...

Expected Outcome:This topic aims at supporting activities that are enabling or contributing to one or several expected impacts of destination “Maintaining an innovative, sustainable, and competitive EU health industry”. To that end, proposals under this topic should aim to deliver results that are directed at, tailored towards and contributing to all the following expected outcomes:Healthcare professionals dispose of diagnostic tools at the point of care that accelerate therapeutic decision making.Patients benefit from fast and accurate diagnosis leading to improved health outcomes.Thanks to more efficient diagnosis, health systems will get better evidence for disease control and prevention strategies. Scope:Point-of-Care (PoC) medical testing has made great technical progress (e.g. improved extraction, microfluidics, miniaturisation, and data processing techniques) with PoC test accurac...

Expected Outcome:Project results are expected to contribute to all of the following expected outcomes:the capacities and integrated governance of researchers, decision-makers, practitioners, local communities and other stakeholders to effectively collaborate to prevent, eradicate or manage invasive alien species (IAS) are enhanced;native ecosystems are better protected, leading to improved resilience and continuous provision of ecosystem services including for climate mitigation and adaptation. Scope:Invasive alien species are one of the five main direct drivers of biodiversity loss. Besides inflicting major damage to nature and the economy, many invasive alien species also facilitate the outbreak and spread of infectious diseases, posing a threat to humans and native wildlife. The rate of new introductions of invasive alien species has increased in recent years. Without effective contro...

Expected Outcome: Project results are expected to contribute to all of the following expected outcomes:land managers, farmers, conservation organizations, researchers, policymakers, and agribusinesses are equipped with the knowledge and tools to implement practices that enhance habitats for farmland birds and mammals, thereby improving pest control, supporting pollination, and strengthening agricultural resilience;challenges, measures, and needs of land managers, farmers and conservation organizations are known and supported via appropriate incentives to facilitate the wide adoption of bird- and mammal-friendly practices. Scope:Maintaining and improving farmland bird populations is crucial for both conservation and the long-term sustainability of food production systems. Farmland birds and mammals provide valuable ecosystem services, such as pest control, pollination, and seed dispersal,...

Expected Outcome:This topic aims at supporting activities that are enabling or contributing to one or several expected impacts of destination “Tackling diseases and reducing disease burden”. To that end, proposals under this topic should aim to deliver results that are directed at, tailored towards and contributing to all the following expected outcomes:Researchers, developers and clinical practitioners have access to state-of-the-art knowledge, data, technologies, tools, methods, best practices, and trainings to develop innovative healthcare interventions aimed at reducing burden of the following specific Non-Communicable Diseases (NCDs): cardiovascular diseases, diabetes, chronic respiratory diseases or chronic kidney diseases.Scientific and clinical communities can use innovative healthcare interventions to generate meaningful advances in clinical practice and care for patients with N...

Expected Outcome:Projects are expected to contribute to all of the following outcomes:Cities and regions are equipped with innovative practices for urban wastewater management, adapted to climate change, taking into account: energy efficiency, energy and secondary raw material recovery and water reuse, including opportunities for renewable energy generation and secondary resource production, implemented at city and regional level.Treatment infrastructures and management solutions are deployed and upscaled for water, storm water and wastewater in cities and regions, with positive effects on climate adaptation, biodiversity, air and water pollution reduction, resource valorisation and energy efficiency.Knowledge is disseminated about innovative practices, governance and business models for integrated (waste)water management, in the context of climate change among relevant stakeholder group...

Expected Outcome:Project results are expected to contribute to all of the following expected outcomes:European industry’s competitiveness, decarbonisation, and strategic autonomy are enhanced through the development and deployment of safe, sustainable, circular and bio-based value chains;improved climate change adaptation and mitigation and overall environmental sustainability, as well as higher resource efficiency, through application of biotechnologies and industrial symbiosis, and recovery of biological materials, water and energy. Scope:The projects under this topic are relevant to the EU policies related to the Commission communication on: Building the future with nature: Boosting Biotechnology and Biomanufacturing in the EU, the Life Sciences Strategy, the EU Biotech Act, Clean Industrial Deal and the SME Strategy. It also contributes to the Start-ups and Scale-ups strategy. Synerg...

Expected Outcome:Projects are expected to contribute to all of the following outcomes:Development of approaches, tools and methods, on how and where to restore, increase and maintain urban green space and tree canopy cover to achieve the greatest positive impacts - on climate mitigation, adaptation and resilience, biodiversity, soil, air and water quality, quality of life, and human health.Uptake and deployment of solutions to map, restore, increase and maintain urban green space and tree canopy cover, via pilot sites in lead cities, including along urban transport networks[1].Monitoring, evaluation and assessment of the environmental, economic, social and health impacts of the solutions deployed in pilot sites, including co-benefits and trade-offs.Dissemination of results to follower cities and relevant target groups in other countries and cities. Scope: To address the expected outcomes...

Expected Outcome:Project results are expected to contribute to all of the following outcomes:  public authorities obtain access to enhanced and innovative modelling capabilities to support air quality planning at various policy levels in a coherent way;society benefits from improved governance processes and effective air quality planning strategies, aiming at mitigating air pollution and reducing population exposure, as well as from far more targeted air pollution alerts;public authorities, including EU policy-makers and the EEA, receive faster, more comprehensive scientific evidence and tools, enabling more effective EU air quality policy implementation and providing citizens with reliable, detailed information and peak pollution warnings to reduce health impacts. Scope:The air we breathe is often polluted, which can lead to serious health problems and even premature death. To address t...