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This Notice of Funding Opportunity (NOFO) encourages applications for investigator-initiated fully remotely delivered and conducted clinical trials to assess the efficacy or effectiveness of complementary and integrative health interventions in NCCIH- designated areas of high research priority. Applications submitted under this NOFO are expected to propose a remotely delivered and conducted fully powered clinical trial with no in-person contact between research staff and study participants and may utilize mHealth tools or technologies. Applicants must provide justification for the remotely delivered approach and provide preliminary data on the feasibility and safety of the approach, along with evidence that the intervention has promise of clinical benefit. Applicants are encouraged to contact the appropriate NCCIH Scientific/Research contact for the area of science for which they are planning to develop an application prior to submitting to this NOFO.

The goal of this notice of funding opportunity (NOFO) is to support feasibility trials of complementary and integrative health approaches with physical and/or psychological therapeutic inputs (often called mind and body interventions) for conditions that have been identified by NCCIH as high-priority research topics. This funding opportunity is intended to support feasibility clinical trials that provide new information that are scientifically necessary for the planning and conduct of a subsequent clinical efficacy or effectiveness study, pragmatic trial, or dissemination and implementation trial within NCCIHs mission. NCCIH expects that applications to this NOFO will describe the planned future clinical trial and in so doing demonstrate that the proposed (R34) research is scientifically necessary to design or plan the subsequent competitive full-scale clinical trial. Under this R34, the data collected should be used to fill gaps in scientific knowledge necessary to develop a competitive full-scale clinical trial, including, but not limited to the following: examining feasibility and acceptability of interventions lacking published data; tailoring or adapting the content or structure of an intervention to a specific population, modality, or setting; refining the intervention to determine the most appropriate frequency or duration; determining feasibility of recruitment, retention, and data collection procedures; refining and assessing the feasibility of protocolized multi-component interventions; or examining acceptability and adherence of control conditions. The subsequent...

This Notice of Funding Opportunity (NOFO) focuses on prevention and intervention strategies for fetal alcohol spectrum disorders (FASD) throughout the lifespan. The intent of this NOFO is to support research that advances (1) prevention approaches to reduce prenatal alcohol exposure and the incidence of FASD and that (2) interventions for FASD. These objectives will be accomplished with the Exploratory/Developmental Phased Award (R61/R33) mechanism, clinical trial optional. The R61 phase will support pilot studies or secondary data analysis for hypothesis development and feasibility, and research testing the hypotheses can be expanded in the R33 phase. The transition to the R33 phase will be determined by NIAAA program staff after evaluation of the achievement of specific milestones set for the R61 phase. Highest priority will be given to applications with clinical trials. Applicants interested in planning clinical trials or adding to current projects may also consider NOFO (TEMP-23832, the R34 option).

Buyer: Gemeente Smallingerland | Notice type: cn-standard | Procedure: open | Contract: supplies | Deadline: 2026-11-18

Buyer: Gemeente Smallingerland | Notice type: cn-standard | Procedure: open | Contract: supplies | Deadline: 2026-11-18

The purpose of this NOFO is to invite Research Project (R01) applications that propose to study the ethical, legal, and social implications (ELSI) of human genetics and genomics. Applications may propose studies using either single or mixed methods. Approaches may include but are not limited to empirical qualitative and quantitative methods, as well as conceptual, legal, and normative analyses. Direct involvement of key stakeholders where appropriate is encouraged. This Notice of Funding Opportunity (NOFO) requires a Plan for Enhancing Diverse Perspectives (PEDP) as part of the application. Applications without a PEDP will not be reviewed.

The purpose of this NOFO is to invite Exploratory/Developmental Research Grant (R21) applications that propose to study the ethical, legal, and social implications (ELSI) of human genetics and genomics. Applications may propose studies using either single or mixed methods. Approaches may include but are not limited to empirical qualitative and quantitative methods, as well as conceptual, legal, and normative analyses. Direct involvement of key stakeholders where appropriate is encouraged. Of particular interest are studies that explore the implications of new or emerging genomic technologies or novel uses of genomic information. 

Buyer: Všeobecná fakultní nemocnice v Praze | Notice type: cn-standard | Procedure: restricted | Contract: supplies | Deadline: 2026-11-19

This NOFO encourages applications for multi-site exploratory and confirmatory clinical trials focused on promising interventions; biomarker or outcome measure validation studies that are immediately preparatory to trials in stroke prevention, treatment, and recovery; and ancillary studies designed to add scientific aims to active studies being conducted within StrokeNet. Successful applicants will collaborate and conduct the study within the NIH StrokeNet. Following peer review, NINDS will prioritize studies among the highest scoring to be conducted in the NIH StrokeNet infrastructure. The NIH StrokeNet National Coordinating Center (NCC) will work with the successful applicant to implement the proposed study efficiently and the National Data Management Center (NDMC) will provide statistical and data management support. The NIH StrokeNet Regional Coordinating Centers (RCCs) and their affiliated clinical sites will provide recruitment/retention support as well as on-site implementation of the clinical protocol.

The purpose of this Notice of Funding Opportunity (NOFO) is to invite applications that bundle independent protocols for phase 1 clinical trials with phase 1b/phase 2a clinical trials to streamline the early-stage evaluation of promising pharmacological interventions for Alzheimer's disease (AD) and Alzheimer's disease-related Dementias (ADRD). Candidate interventions evaluated through this program, which can include small molecules or biologics for example, must engage non-amyloid/non-tau mechanisms and aim to address cognitive and/or neuropsychiatric symptoms in individuals across the spectrum from pre-symptomatic to more severe stages of disease. This NOFO uses the UG3/UH3 phased award mechanism and proposals must include prespecified, go/no-go safety and tolerability milestones that gate the advance from phase 1 to latter stages of clinical development.

Buyer: Państwowe Gospodarstwo Leśne Lasy Państwowe Nadleśnictwo Szczytno | Notice type: pin-rtl | Procedure: open | Contract: services | Deadline: 2026-11-20

Buyer: UBS | Notice type: cn-standard | Procedure: open | Contract: services | Deadline: 2026-11-20

Buyer: Všeobecná fakultní nemocnice v Praze | Notice type: cn-standard | Procedure: restricted | Contract: supplies | Deadline: 2026-11-22

Buyer: Louth and Meath Education and Training Board 1384 | Notice type: cn-standard | Procedure: open | Contract: services | Deadline: 2026-11-23

Buyer: Ochotnicza Straż Pożarna w Międzyrzeczu Górnym | Notice type: cn-standard | Procedure: open | Contract: supplies | Deadline: 2026-11-24

Buyer: Ochotnicza Straż Pożarna w Rudzicy | Notice type: cn-standard | Procedure: open | Contract: supplies | Deadline: 2026-11-24

Buyer: Ochotnicza Straż Pożarna w Grodźcu | Notice type: cn-standard | Procedure: open | Contract: supplies | Deadline: 2026-11-24

Buyer: Ochotnicza Straż Pożarna w Jasienicy | Notice type: cn-standard | Procedure: open | Contract: supplies | Deadline: 2026-11-24

Buyer: Krajowa Izba Odwoławcza | Notice type: cn-standard | Procedure: open | Contract: supplies | Deadline: 2026-11-24

Buyer: Ochotnicza Straż Pożarna w Mazańcowicach | Notice type: cn-standard | Procedure: open | Contract: supplies | Deadline: 2026-11-24

The National Institutes of Health (NIH) hereby notifies NIH award recipients that funds may be available for revision applications to support the expansion of existing projects and/or programs within the awarding IC identified in the competitive revision Notice of Special Interest (NOSI). Applications for Revisions will be evaluated for scientific and technical merit by (an) appropriate Scientific Review Group(s), in accordance with NIH peer review policy and procedures, using the stated review criteria. Only applications submitted in response to a NOSI published by an NIH Institute or Center will be allowed to apply to this NOFO.

Buyer: Azienda Sociale | Notice type: cn-standard | Procedure: open | Contract: services | Deadline: 2026-11-26

Buyer: Città metropolitana di Torino | Notice type: cn-standard | Contract: services | Deadline: 2026-11-26

Buyer: Louth and Meath Education and Training Board 1384 | Notice type: cn-standard | Procedure: open | Contract: services | Deadline: 2026-11-26

Buyer: RESAH | Notice type: cn-standard | Procedure: open | Contract: supplies | Deadline: 2026-11-26