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Summary: The fiscal year 2026 (FY26) Autism Research Program (ARP) Career Development Award supports early-career, independent investigators and/or the transition of established investigators from other research fields to conduct innovative, high-impact ideas or early-phase, proof-of-principle clinical trials with the potential to have a major impact on autism.Distinctive Features: Applications are strongly encouraged to address one of the FY26 ARP Career Development Award Areas of Interest or provide justification that the proposed research addresses a critical problem, question, or need in autism.FY26 Career Development Award submissions with a pilot clinical trial component are required to include community collaborations to optimize research impact. Applications are expected to name at least one community partner (e.g., an Autistic individual or caregiver, representatives of community-based organizations) who will provide advice and consultation throughout the planning and implementation of the research project.

Summary: The fiscal year 2026 (FY26) Autism Research Program (ARP) Idea Development Award supports the development of innovative, high-risk/high-reward research that could lead to critical discoveries or major advancements that will accelerate progress in improving outcomes for Autistic individuals. This award mechanism is designed to support innovative ideas with the potential to yield impactful data and new avenues of investigation.Distinctive Features: Applications are strongly encouraged to address one of the FY26 ARP Idea Development Award Areas of Interest or provide justification that the proposed research addresses a critical problem, question, or need in autism.Partnering Principal Investigator (PI) Option: The Partnering PI Option is structured so that two investigators, each of whom will be designated as a PI, will work synergistically on a single project. The results of this partnering project should significantly advance the research beyond what would be possible through individual efforts.

Summary: The fiscal year 2026 (FY26) Autism Research Program (ARP) Clinical Trial Award supports the rapid implementation of clinical trials with the potential to have a significant impact on the treatment or management of autism. Clinical trials may be designed to evaluate promising new products, pharmacologic agents (drugs or biologics), devices, clinical guidance and/or emerging approaches and technologies. Proposed projects may range from small proof-of-concept trials (e.g., pilot, first-in-human, phase 0) to demonstrate the feasibility or inform the design of more advanced trials through large-scale trials to determine efficacy in relevant patient populations.Distinctive Features: Applications are strongly encouraged to address one of the FY26 ARP Clinical Trial Award Areas of Interest.Partnering Principal Investigator (PI) Option for Early-Career Investigator: The FY26 Clinical Trial Award mechanism is offering a higher level of funding for applications that propose to partner an experienced PI (i.e., Initiating PI) with an Early-Career Investigator (i.e., Partnering PI) wishing to pursue a career in autism clinical trial research.FY26 Clinical Trial Award submissions are required to include community collaborations to optimize research impact. Research teams are therefore required to establish and utilize effective and equitable collaborations and partnerships with community members to maximize the translational and impact potential of the proposed research. Applications to the FY26 ARP Clinical Trial Award are expected to name at least one community partner (e.g., A...

In 2016, the National Science Foundation (NSF) unveiled a set of “Big Ideas,” 10 bold, long-term research and process ideas that identify areas for future investment at the frontiers of science and engineering (see https://www.nsf.gov/news/special_reports/big_ideas/index.jsp). The Big Ideas represent unique opportunities to position our Nation at the cutting edge of global science and engineering leadership by bringing together diverse disciplinary perspectives to support convergence research. As such, when responding to this solicitation, even though proposals must be submitted to the Directorate for STEM Education (EDU) / Division of Equity for Excellence in STEM (EES), once received, the proposals will be managed by a cross-disciplinary team of NSF Program Directors. The INCLUDESInitiative is a comprehensive, national effort to enhance U.S. leadership in science, technology, engineering, and mathematics (STEM) discovery and innovation, focused on NSF’s commitment to ensuring accessibility and inclusivity in STEM fields, as communicated in the NSF Strategic Plan for Fiscal Years (FY) 2022 - 2026. The vision of the INCLUDES Initiative is to catalyze the STEM enterprise to work collaboratively for inclusive change, resulting in a STEM workforce that reflects the Nation’s population. More specifically, the INCLUDES Initiative seeks to motivate and accelerate collaborative infrastructure building to sustain systemic change to broaden participation in STEM fields at scale.Significant advancement of the INCLUDES Initiative's goalswill result in a new generation of STEM talent a...

The CHIPS Incentives Program aims to catalyze long-term economically sustainable growth in the domestic semiconductor industry in support of U.S. economic and national security. This is the second Notice of Funding Opportunity under this program and seeks applications for projects for the construction, expansion, or modernization of commercial facilities for semiconductor materials and manufacturing equipment. For more information, additional resources, and instructions on how to apply, please visit chips.gov. Note that all applications must be submitted through the CHIPS Incentives Portal at https://applications.chips.gov. If you have any questions on how to apply, please email apply@chips.gov.

The Topology program supports research on algebraic topology, including chromatic, equivariant, motivic, and (un)stable homotopy, homology and cohomology theories; bordism and K-theory; topological manifolds; knots and links; geometric topology; differential topology; transformation groups; topological quantum field theories; contact and symplectic structures; infinity and model categories; and topological data analysis. Conferences Topology proposals for conferences, workshops, summer/winter schools, and similar activities must be submitted to PD 22-1267 using the "Conference" or “Travel” proposal type in research.gov. The program’ssubmission windows for conference/travel proposalsare September 1-30 and April 1-30. Proposals with budgets not exceeding $50,000 should be submitted during a submission window that occursat least six months prior to the event. Proposals with budget requests that exceed $50,000 should be submitted during a submission window that occursat least eight months prior to the event. Principal Investigators should carefully read the relevant sections of the PAPPG to obtain important information regarding the substance of such proposals and note the additional requirements for travel support requests for international events.

The program in Geometric Analysis supports research on differential geometry and its relation to partial differential equations and variational principles; geometric methods in modern mathematical physics; symplectic geometry; geometric group theory; geometric data analysis; aspects of global analysis, including convex, complex, integral, and information geometries; and related geometric topics. Conferences Geometric Analysis proposals for conferences, workshops, summer/winter schools, and similar activities must be submitted to PD 22-1265 using the "Conference" or “Travel” proposal type in research.gov. The program’s submission windows for conference/travel proposals are September 1-30 and April 1-30. Proposals with budgets not exceeding $50,000 should be submitted during a submission window that occursat least six months prior to the event. Proposals with budget requests that exceed $50,000 should be submitted during a submission window that occursat least eight months prior to the event. Principal Investigators should carefully read the relevant sections of the PAPPG to obtain important information regarding the substance of such proposals and note the additional requirements for travel support requests for international events.

The Directorate for Social, Behavioral and Economic Sciences (SBE) offers Postdoctoral Research Fellowships to encourageindependence earlyin the fellow'scareerby supporting his or herresearch and training goals.The research and training plan of each fellowship must address important scientific questions within thescope of the SBE directorate and the specific guidelines in this solicitation. The SPRF program offers two tracks: (I) Fundamental Research in the SBE Sciences (SPRF-FR) and (II) Broadening Participation in the SBE Sciences (SPRF-BP). See the full text of the solicitation for a detailed description of these tracks.

Summary: The fiscal year 2026 (FY26) Spinal Cord Injury Research Program (SCIRP) Translational Research Award (TRA) supports translational research that will accelerate the movement of promising ideas in spinal cord injury (SCI) research into clinical applications.Distinctive Features:• This funding opportunity contains an Early-Career Partnership Option, which allows for two principal investigators (PIs). If this option is selected, at least one of the named PIs must be an early-career investigator. Only the initiating PI will submit a pre-application, but all PIs will need to submit full applications. The partnering PI’s application is an abbreviated package specific to their distinct portion of the research project. If recommended for funding, each PI will be named on a separate award to the recipient organization(s). Be advised, all associated applications for a research project may be withdrawn if the initiating or partnering application is rejected or administratively withdrawn.• Applications to this funding opportunity must name at least one SCI community partner (e.g., SCI Lived-Experience Consultant, representative of community-based organizations) who will provide advice and consultation throughout the planning and implementation of the research project.

Summary: The fiscal year 2026 (FY26) Spinal Cord Injury Research Program (SCIRP) Investigator-Initiated Research Award (IIRA) supports studies that have the potential to make an important contribution to spinal cord injury (SCI) research, patient care and/or quality of life. May focus on any phase of research from basic through translational science, though studies that focus solely on identifying intervention targets are discouraged.Distinctive Features:• This funding opportunity contains an Early-Career Partnership Option, which allows for two Principal Investigators (PIs). If this option is selected, at least one of the named PIs must be an early-career investigator. Only the initiating PI will submit a pre-application, but all PIs will need to submit full applications. The partnering PI’s application is an abbreviated package specific to their distinct portion of the research project. If recommended for funding, each PI will be named on a separate award to the recipient organization(s). Be advised, all associated applications for a research project may be withdrawn if the initiating or partnering application is rejected or administratively withdrawn.

Summary: The fiscal year 2026 (FY26) Vision Research Program (VRP) Investigator-Initiated Research Award (IIRA) supports basic through early translational research that will yield highly impactful discoveries or major advancements in the research and/or patient care of eye injury and/or visual dysfunction related to military exposure. The IIRA may be used to support preclinical studies and/or clinical research. Research must align with at least one of the FY26 VRP Focus Areas. The IIRA cannot be used to support clinical trials. Distinctive Features: ·        The IIRA offers two Funding Levels to support research at different stages and the exploration/development of ideas of different maturity levels. ·        Funding Level 2 includes a Partnering Principal Investigator (PI) Option (PPIO) for two PIs, an Initiating PI and a Partnering PI. ·        Scored peer review criteria include Research Idea/Rationale, Research Strategy and Feasibility, Impact, and Personnel. ·        Programmatic review criteria include adherence to the intent of the IIRA, contribution to the VRP portfolio, relative impact, and relevance to military health. ·        The VRP may share FY26 IIRA applications and reviews with the National Eye Institute (NEI) for independent funding consideration. https://cdmrp.health.mil/pubs/press/2026/vrppreann

Summary: The fiscal year 2026 (FY26) Vision Research Program (VRP) Clinical Trial Award (CTA) supports the rapid implementation of clinical trials with the potential to have a significant impact on the treatment or management of service-connected eye injury and visual dysfunction. Research must align with at least one of the FY26 VRP Focus Areas.   Distinctive Features: ·       For interventions that require Investigational New Drug (IND)/Investigational Device Exemption (IDE) or equivalent regulatory authorizations for clinical testing, the IND/IDE application or equivalent must be submitted to the relevant Regulatory Agency by the CTA application submission deadline. In addition, applicants must provide documentation of communication from the Regulatory Agency indicating that the IND/IDE or equivalent is active/safe to proceed by March 1, 2027, in order for the CTA application to be considered for funding. Refer to Attachment 7: Regulatory Strategy for further details. ·       Scored peer review criteria include Clinical Impact; Research Strategy and Feasibility; Recruitment, Accrual, Retention; Regulatory Strategy and Transition Plan; Statistical Plan and Data Analysis; Ethical Considerations; Personnel and Communication. ·       Programmatic review criteria include adherence to the intent of the CTA, contribution to program portfolio, relative impact and relevance to military health. https://cdmrp.health.mil/pubs/press/2026/vrppreann

Summary: The fiscal year 2026 (FY26) Spinal Cord Injury Research Program (SCIRP) Clinical Trial Award (CTA) supports the rapid implementation of clinical trials with the potential to have a significant impact on the treatment or management of spinal cord injury (SCI).Distinctive Features: This funding opportunity contains an Early-Career Partnership Option, which allows for two Principal Investigators (PIs). If this option is selected, at least one of the named PIs must be an early-career investigator. Only the Initiating PI will submit a pre-application, but all PIs will need to submit full applications. The Partnering PI’s application is an abbreviated package specific to their distinct portion of the research project. If recommended for funding, each PI will be named on a separate award to the recipient organization(s). Be advised, all associated applications for a research project may be withdrawn if the initiating or partnering application is rejected or administratively withdrawn.Applications to this funding opportunity must name at least two spinal cord injury (SCI) community partners (e.g., SCI Lived-Experience Consultants, representatives of community-based organizations) who will provide advice and consultation throughout the planning and implementation of the research project.

Summary: The fiscal year 2026 (FY26) Spinal Cord Injury Research Program (SCIRP) Clinical Translation Research Award (CTRA) supports high-impact, new, or emerging clinical research that requires additional preliminary studies, such as feasibility, pilot, or optimization, to prepare for future larger-scale clinical trials or implementation. Primary objectives of this mechanism include:• Accelerating the translation of current and emerging techniques or interventions into clinical use by addressing specific barrier(s) to clinical success for the purpose of de-risking or informing the design of definitive trials.• Identifying the most effective diagnosis, treatment and rehabilitation options to support critical decision-making for patients, clinicians, care partners and policymakers.Distinctive Features:• This funding opportunity contains an Early-Career Partnership Option, which allows for two principal investigators (PIs). If this option is selected, at least one of the named PIs must be an early-career investigator. Be advised, all associated applications for a research project may be withdrawn if the initiating or partnering application is rejected or administratively withdrawn.• Applications to this funding opportunity must name at least two spinal cord injury (SCI) community partners who will provide advice and consultation throughout the planning and implementation of the research project.

Summary: The fiscal year 2026 (FY26) Vision Research Program (VRP) Translational Research Award (TRA) supports translational research that transforms a promising discovery into new drugs, devices or clinical practice guidelines that are ready for definitive testing in clinical trials during or by the end of the period of performance. The TRA may be used to support preclinical studies, clinical research or a pilot clinical trial, but not a full-scale clinical trial. Research must align with at least one of the FY26 VRP Focus Areas. Distinctive Features: ·        If developing new drugs or device(s), the research team must include expertise in the regulatory approval process. ·        The TRA includes a Partnering Principal Investigator (PI) Option (PPIO) for two PIs, an Initiating PI and a Partnering PI. ·        Scored peer review criteria include Research Idea/Rationale, Research Strategy and Feasibility, Impact, Personnel and Post-Award Transition Plan. ·        Programmatic review criteria include adherence to the intent of the TRA, contribution to the VRP portfolio, relative impact and relevance to military health. ·        The VRP may share FY26 TRA applications and reviews with the National Eye Institute (NEI) for independent funding consideration. https://cdmrp.health.mil/pubs/press/2026/vrppreann

The Advanced Technologies and Instrumentation for the Astronomical Sciences (ATI) program provides individual investigator and collaborative research grants for the development of new technologies and instrumentation for use in ground-based astronomy and astrophysics.The program supports achieving the science objectives of the Division of Astronomical Sciences. The development of innovative, potentially transformative, technologies and instruments are sought, even at high technical risk.Supported categories include (but are not limited to):advanced technology development, concept feasibility studies, and specialized instrumentation to enable new observations that are difficult or impossible to obtain with existing means.Proposals may include hardware and/or software development and/or analysis to enable new types of astronomical observations. Access to the ATI supported technology and instrumentation development efforts by the US astronomical community is viewed as an important metric of success. An annual Principal Investigators meeting is planned to disseminate information between the funded research efforts.

The Major Research Instrumentation (MRI) Program (MRI Program Website) serves to increase access to multi-user scientific and engineering instrumentation for research and research training in our Nation's institutions of higher education and not-for-profit scientific/engineering research organizations. An MRI award supports the acquisition of a multi-user research instrument that is commercially available through direct purchase from a vendor, or for the personnel costs and equipment that are required for the development of an instrument with new capabilities, thereby advancing instrumentation capabilities and enhancing expertise for instrument design and fabrication at academic institutions. MRI instruments are, in general, too costly and/or not appropriate for support through other NSF programs. MRI provides support to acquire critical research instrumentation without which advances in fundamental science and engineering research may not otherwise occur. MRI also provides support to obtain next-generation research instruments by developing instruments with new capabilities that open new opportunities to advance the frontiers in science and engineering research. Additionally, an MRI award is expected to enhance research training of students who will become the next generation of instrument users, designers and builders. An MRI proposal may request from NSF up to $4 million for either acquisition or development of a research instrument. Each performing organization may submit in revised "Tracks" as defined below, with no more than two (2) submissions in Track 1 and no more....

The Astronomy and Astrophysics Research Grants (AAG) Program is an inclusive and flexible funding opportunity to support research in the astronomical sciences. The Program provides individual investigator and collaborative research grants for observational, theoretical, laboratory, and archival data studies in astronomy and astrophysics. The Program also considers proposals for projects and tools that enable or enhance astronomical research. Proposals may span multiple disciplines and/or areas of study and may utilize multiple techniques.

Proposals in the area of plasma physics submitted to the Division of Physics that are not governed by another solicitation (such as CAREER), should be submitted to the Division-wide solicitation: Division of Physics: Investigator-Initiated Research Projects. The Plasma Physics program participates in multiple NSF meta-programs such as the ECosytem for Leading Innovation in Plasma Science and Engineering (ECLIPSE), Windows on the Universe: The Era of Multi-Messenger Astrophysics (WoU-MMA), and Computational and Data-enabled Science and Engineering (CDS&E). Topically appropriate proposals may also be submitted to the Plasma Physics program in response to NSF Dear Colleague Letters such as Critical Aspects of Sustainability (CAS): Innovative Solutions to Sustainable Chemistry (CAS-SC). When permitted under an MOU between NSF and another funding agency or private foundation, NSF may share information from proposals submitted to this solicitation for consideration of joint funding, and may invite employees of such organizations to attend merit review panels as observers. MOUs of relevance to the Plasma Physics program presently exist with the Department of Energy/Office of Science, National Nuclear Security Administration, the Air Force Office of Scientific Research, the US-Israel Binational Science Foundation, the Czech Science Foundation, Deutsche Forschungsgemeinschaft (DFG, German Research Foundation), and the Swiss National Science Foundation. Plasma Physics is a study of matter and physical systems whose intrinsic properties are governed by collective interactions of large...

The Applied Mathematics program supports mathematics research motivated by and contributing to the solution of problems arising in science and engineering. Successful proposals must demonstrate mathematical innovation, as well as breadth and quality of impact on applications. Projects that additionally provide opportunities for rigorous mathematical training of junior applied mathematicians through their involvement in research are encouraged. The proposals considered by the Applied Mathematics program may range from single investigator to interdisciplinary team projects. Conferences Proposals to the Applied Mathematics program for conferences or workshops should be submitted through the program solicitation "Conferences and Workshops in the Mathematical Sciences" (link below). Principal Investigators should carefully read the program solicitation to obtain important information regarding the substance of proposals for conferences, workshops, summer/winter schools, and similar activities. To facilitate timely notification of the availability of support: Proposals for conferences, workshops, etc., to be held in the US must be submitted 8 months in advance of the conference date; Proposals to support group travel to meetings outside the US must be submitted 12 months in advance of the meeting date; Proposals for conferences, workshops, etc., whose budget request exceeds $50,000 must be submitted during the annual November submission window.

The proposed topic will develop and mature Communications and Networking technologies for Naval operations.Background:A Design for Maritime Superiority (2018) describes an operational architecture for distributed maritime operations (DMO) that "... will provide accurate, timely, and analyzed information to units, warfighting groups, and fleets." A critical component of this architecture is the Naval Tactical Grid (NTG) to connect distributed units into groups and distributed groups into fleets.Communications and networking technologies that can provide seamless, robust, connectivity are key enablers for the NTG. These technologies will be deployed on a variety of platforms, both manned and unmanned, operating under challenging environmental and operational warfare conditions (lack of infrastructure, mobility, spectrum limitations, interference, multipath, atmospherics, jamming, electronic intercept, size/weight/power constraint, etc.) in different domains (land, maritime [includes both surface and undersea], cyber, and space). SuccessfulCommand and Control (C2) and decision making, at all levels of command, for DMO is critically dependent on these communications and networking technologies

The NSF FINDERS FOUNDRY program supports collaboration among K-12 educators, technologists, and researchers to develop innovative solutions to persistent challenges in learning and workforce development. These challenges are identified by K-12 students, families, and educators. The program aims to create and scale evidence-based practices, tools, and technologies that improve learning outcomes and prepare students for a digital, Artificial Intelligence (AI)-driven future. A key focus is early exposure to AI to build curiosity, understanding, and readiness for future careers. The program encourages partnerships across sectors - schools, universities, industry, government, and nonprofits - to co-design responsive, technology-based solutions. NSF FINDERS FOUNDRY program includes two phases: Planning and Development. Planning proposals help teams explore one of several focus areas. Only teams awarded Planning grants may submit Development proposals, which support the growth and implementation of promising ideas. The program aligns with national priorities, including the Executive Order 14277, “Advancing Artificial Intelligence Education for American Youth” (April 23, 2025), and the CHIPS and Science Act of 2022, Public Law 117-167, Sections 10381-10383 and 10395.

Summary: The intent of the fiscal year 2026 (FY26) Toxic Exposures Research Program (TERP) Translational Research Award (TRA) is to support translational research that will accelerate the movement of promising ideas in military-related toxic exposure research into clinical applications, including health care products, interventions, technologies and/or clinical practice guidelines. Translational research may be defined as an integration of basic science and clinical observations. New Approach Methodologies may also be used. Applications should provide evidence for the reciprocal transfer of information between basic and clinical science, or vice versa, in developing and implementing the research plan.  Distinctive Features: To encourage applications that include meaningful and productive collaborations, the FY26 TERP TRA includes a Partnering Principal Investigator Option (PPIO). One Principal Investigator (PI) is identified as the initiating PI, and an additional PI may be identified as a Partnering PI. If recommended for funding, each PI will be named on separate awards. The intent is to support interdisciplinary partnerships, such as those between clinicians and research scientists, that will accelerate the movement of promising ideas into clinical applications. Partnering should significantly advance the research beyond what would be possible through individual efforts. https://cdmrp.health.mil/pubs/press/2026/terppreann

Summary: The fiscal year 2026 (FY26) Toxic Exposures Research Program (TERP) Clinical Trial Award (CTA) mechanism supports the advancement, execution, and analysis of clinical trials with the potential to have a significant impact on the prevention, treatment, or management of symptoms, diseases or conditions associated with or resulting from military-related toxic exposures. Proposed projects may range from small proof-of-concept clinical trials (e.g., pilot, first-in-human, phase 0) designed to demonstrate the feasibility or inform the design of more advanced trials, through large-scale trials (including pragmatic clinical trials) to determine efficacy in relevant patient populations.  Distinctive Features: To encourage applications that include meaningful and productive collaborations, the FY26 TERP CTA includes a Partnering Principal Investigator Option (PPIO). One Principal Investigator (PI) is identified as the initiating PI, and an additional PI may be identified as a Partnering PI. If recommended for funding, each PI will be named on separate awards. The intent is to support interdisciplinary partnerships, such as those between clinicians and research scientists, that will accelerate the movement of promising interventions/​knowledge products into clinical applications. Partnering should significantly advance the research beyond what would be possible through independent efforts. https://cdmrp.health.mil/pubs/press/2026/terppreann

Summary: The fiscal year 2026 Toxic Exposures Research Program (TERP) Investigator-Initiated Research Award (IIRA) is intended to support studies that will make an important contribution toward research and/or patient care for diseases or conditions associated with military-related toxic exposures. Research projects may focus on any phase of research from basic laboratory research through translational research, including preclinical studies in animal models and human subjects, as well as correlative studies associated with an existing clinical trial. New Approach Methodologies may also be used. https://cdmrp.health.mil/pubs/press/2026/terppreann