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The purpose of the Resource-Related Research Projects (R24) grant is to support investigator-initiated resources designed to provide materials and services to support and advance biomedical research on a national basis. An R24 resource grant mechanism is a non-hypothesis-driven activity to provide data, materials, tools, or services that are essential to making timely, high quality, and cost-efficient progress in a field. Hypothesis-driven research applications should not be submitted in response to this program announcement but to another mechanism that encourages this type of research. The resource should be available to any qualified investigator, and should be highly quality controlled, and not duplicate resources available commercially or through other sources. Resources should be designed to provide services to the broad alcohol research community and should not be limited by any specific regional focus.

The Office of Research Infrastructure Programs (ORIP) invites grant applications from core facilities, resource centers, animal vivaria, or individual investigators of other shared resources to systematically study the roles of critical environmental extrinsic factors in biological, behavioral, and treatment studies using animal model species, with the objective of enhancing the rigor and reproducibility of animal research. The research area must be broadly applicable to the scientific interests of two or more NIH Institutes or Centers (ICs) and must evaluate the biological processes that impact multiple organ systems in order to align with the ORIPs NIH-wide mission and programs. The program supports the acquisition or update of modern equipment for measuring, monitoring, recording, and reporting environmental, biological or biobehavioral variables. The equipment requested must be capable of recording and reporting multiple parameters simultaneously.

This Notice of Funding Opportunity (NOFO) invites eligible academic or research institutions to apply for funding support to purchase latest scientific equipment that will enhance and modernize research-supporting operations of existing shared biomedical research facilities. Targeted are laboratory research core facilities, animal research facilities, and other similar shared-use research spaces. The goal of this NOFO is to strengthen research-auxiliary activities of biomedical research facilities and to enhance the efficiency of their operations. The NOFO does not support the purchase of scientific research instruments or their components, nor components of building-level infrastructure equipment that indirectly support research activities.

The specific purpose of this Notice of Funding Opportunity (NOFO) is to promote the development of a diverse, interdisciplinary workforce needed to conduct translational research on Alzheimer's disease and Alzheimer's-related dementias from target discovery through clinical development. This NOFO will support institutional training programs for predoctoral and postdoctoral level researchers with diverse educational backgrounds (i.e., basic biology, translational and clinical research, data science). The program invites eligible institutions to develop interdisciplinary training programs that will provide trainees with the knowledge and skills in data science, disease biology, behavioral research, and traditional and emerging drug discovery disciplines necessary to conduct rigorous and cutting-edge basic, translational, and clinical research for AD/ADRD.

The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH. The overarching goal of this R25 program is to encourage individuals who have not had substantial biomedical research experience, or who have the potential to significantly benefit from additional biomedical research experience to pursue further studies or careers in research. To accomplish the stated over-arching goal, this NOFO will support educational activities with a primary focus on: (1) Research Experiences, (2) Curriculum or Methods Development and (3) Outreach. The NCI’s mission is to conduct and support research, training, health information dissemination, and other programs concerning cancer. This funding opportunity seeks to facilitate educational activities that encourage students to become knowledgeable about cancer and available to focus on cancer later in their careers. To promote broad interest in pursuing a career in biomedical research via early intervention strategies, the NCI Youth Enjoy Science (YES) Program will support efforts to create and maintain an institutional program to engage grades 6-12 and/or undergraduate students in cutting edge cancer research experiences. The proposed institutional programs may also provide research experiences for the grade 6-12 teachers and undergraduate faculty members. The goals are to inspire interest in biomedical sciences, help envision research as a career path, and strengthen practical research and career skills. In alignment with these goals, institutions may develop unique programs that capitalize....

The purpose of the High Impact Specialized Innovation Programs (SIPs) is to support the development and demonstration of unique hub capabilities, research platforms and/or resources to address in a timely manner critical gap areas and/or roadblocks in clinical and translational science at awarded UM1 Clinical and Translational Science Awards (CTSA) Program Hubs (PAR-24-272). Successful programs supported through this funding opportunity are expected to lay a strong foundation for future adoption and/or dissemination of capabilities to additional CTSA Program Hubs.

Our world is at a pivotal moment where the boundaries dividing the physical and social worlds from the cyber world have become blurred. Cyberspace has evolved from an interconnected digital environment into a complex and interdependent cyber ecosystem that involves hardware, software, networks, data, people, organizations, countries, and the physical world. Critical functions of everyday life are deeply intertwined with computing, including health, government, commerce, the public sphere, education, critical infrastructure, interpersonal communication, and transportation. The complexity and inter-dependencies in cyberspace can be misused and exploited by malicious actors. These in turn can trigger adverse outcomes such as disruption of critical infrastructure and systems; theft of intellectual property and sensitive data; amplification of inequalities; disclosure of private information of individuals, organizations, and governments; and threats to lives, livelihoods, and reputations. Furthermore, constant attacks on the data and assets of corporations, governments, and individuals undermine people’s trust in decision-making and processes that depend critically on these cyber systems. The Security, Privacy, and Trust in Cyberspace (SaTC 2.0) program aims to build trust in global cyber ecosystems. Trust is the core tenet of this program and, for the purposes of this solicitation, is broadly defined to include our confidence in the security, privacy, and resilience of cyberspace, particularly in the face of malicious intent. Achieving this level of confidence in cyberspace req...

The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH. The overarching goal of this NIDCD R25 program is to support educational activities that help recruit individuals with specific specialty or disciplinary backgrounds to research careers in biomedical, behavioral and clinical sciences.

The integration of Artificial Intelligence (AI) and Biological Research has the potential to pave the way for breakthroughs in biotechnology and bio-system design that will create innovations, new industries, and jobs. To capitalize on this promise, the Directorate for Biological Sciences (BIO) will make awards for Postdoctoral Research Fellowships in Biology (PRFB) to recent doctoral degree recipients, for proposals with a research and training focus at the Intersection of Artificial Intelligence and Biological Sciences to Strengthen and Safeguard Biotechnology Innovations. Applying AI to highly complex biological systems will reveal unknown mechanisms in the natural world that hold promise for technological developments. Candidates with AI and/or biology experience will develop deep expertise in both by proposing additional training in both areas. These combinations of current expertise and new cross-training will produce scientists who work seamlessly at the intersection of AI and biology. The fellows are expected to become field leaders who use AI capabilities to extrapolate from biological data to technological advances. Proposers are encouraged to consider how to leverage the nation’s diversity of existing biological data, and biological infrastructure, such as Biofoundries, Programmable Cloud Labs, Manufacturing USA Institutes, and NEON, to accelerate discovery, innovation and the biotechnology that improves human lives, promotes the U.S. economy, and benefits the nation.

Scope:Smart and multifunctional textiles allow various components and devices to be integrated into uniforms and soldier systems. This extends their range of functions, which can include environmental and physiological monitoring of the soldier, localisation, communication, protective functions (e.g. concealing a soldier's visual, radar and electromagnetic signatures from enemy sensors and surveillance technologies, fire protection and neutralisation of hazardous chemicals). Russia’s war of aggression against Ukraine has highlighted the critical operational need for protection of dismounted soldiers, particularly against drones, and triggered the definition of updated soldier system requirements.The objective of this topic is to follow up and complement previous activities in the field of smart and multifunctional textiles with a view to developing an individual camouflage solution, both...

Scope:Due to the changing overall geopolitical context, Member States, EDF associated countries and their land forces need to improve their indirect fire and rocket artillery capabilities in particular, as many have been relying on non-European systems that are already approaching the end of their operational life.Against this background, this topic aims to develop multiple rocket launcher solutions capable of countering the latest threats by increasing the range and precision of indirect fire, maximising interoperability and optimising the cost-effectiveness of operations in a high-intensity and GNSS-contested battle scenario.This topic contributes to the STEP objectives as defined in the STEP Regulation in the target investment area of defence technologies. Targeted types of activities: Studies and design, not excluding upstream and downstream activities eligible for development action...

Scope:The increasing complexity of military operations requires more advanced electronic warfare (EW) systems capable of dealing with multiple threats and operating in electromagnetic congested scenarios. Current solutions are partially effective and require the complex integration of different sensors and frequency bands. As a result, there is a growing need for automated EW systems that can rapidly identify and respond to threats, especially given the limited availability of qualified personnel.To meet this challenge, this topic aims to further develop and integrate technologies to develop a more robust, cognitive and operational EW system. Cognitive EW systems that use AI and machine learning can detect, learn and interact with the environment, accelerating the development and implementation of next-generation EW threat detection, suppression and neutralisation technologies. These sys...

Scope:This topic aims to develop a prototype of a semi-autonomous remote management system, integrated with adaptive hardware that continuously learns and improves its ability to identify and dispose of potential objects. The primary objective is to detect and dispose of ammunition waste and residues from military training areas and battlefields. This will significantly reduce the risk factor associated with human involvement, ultimately contributing to a cleaner environment and in line with the ‘green military’ concept.The performance of the system to be developed is expected to improve over time, allowing it to expand its capabilities and cover larger areas.Beyond defence technologies, this topic also contributes to the STEP objectives as defined in the STEP Regulation in the target investment area of clean and resource-efficient technologies.Targeted types of activities: Studies, desi...

Scope:The objective of this topic is to follow up and complement previous activities in the field of smart technologies for next generation fighter systems. It aims to explore future architectures and develop key technologies, including with proofs of concept, demonstrations and prototypes, for the next generation of military integrated modular avionics for use on a variety of military aerial platforms, both manned and unmanned aircraft, in the context of a defence air cloud.This topic contributes to the STEP objectives as defined in the STEP Regulation in the target investment area of defence technologies. Targeted types of activities: Integrating knowledge, studies, design and system prototyping, not excluding upstream and downstream activities eligible for development actions.Indicative budget: EUR 25 000 000 for this topic under the EDF-2026-DA call.Indicative number of proposals to...

Scope:Taking into consideration the ongoing activities in this area funded by the EU, EU Member States and EDF associated countries, the general objective of this topic is to support the developments necessary for the integration and qualification of Public Regulated Service (PRS) receivers into existing military operational platforms as well as the enhancement of navigation warfare (NAVWAR) capabilities. In particular, this topic will focus on the development of Galileo PRS receiver technology and the NAVWAR information management system, taking into account the need to also support guided munitions and missiles in operational environments.Beyond defence technologies, this topic also contributes to the STEP objectives as defined in the STEP Regulation in the target investment area of deep and digital technologies.Targeted types of activities: Design, system prototyping, testing and qual...

Scope:The aim of this topic is to follow up and complement previous activities in the field of the next generation self-protection systems in order to increase the survivability of fixed wing and rotary wing, combat or non-combat aircraft in hostile environments.This topic is aimed at modular integration with both fixed and rotary wing aircraft, providing protection against direct and indirect threats based on open architecture and international standards, while protecting sensitive data and ensuring compatibility with other platforms. Key features include automatic coordination of countermeasures, threat detection and classification, and the ability to operate in complex environments. For indirect threats, the system should gather intelligence, disrupt enemy tracking and enable collaborative protection with other platforms.This topic contributes to the STEP objectives as defined in the...

Scope:This topic aims to follow up and complement previous activities in the field of high- performance energy systems, with a particular focus on unexplored technologies such as hydrogen (conversion, storage and logistics). New use cases for stationary military applications will therefore be identified and defined, while innovative building blocks and functional modules will be developed and evaluated. The demonstrators’ power and energy targets and other key performance indicators, including life cycle considerations, are expected to be improved, while the operability and connectivity to the energy grid systems of operational bases will be improved.In addition, this topic aims to advance the creation, revision or consolidation of military standards for products and processes for energy generation, distribution and storage.Beyond defence technologies, this topic also contributes to the...

Scope:Reducing administrative barriers remains a challenge for the rapid movement of armed forces across the borders of EU Member States and EDF associated countries, especially in a constantly deteriorating geopolitical environment. The digitisation of the military mobility permit and clearance landscape is therefore crucial for rapid and efficient deployments.Against this background, this topic aims to follow up and complement activities in this area with the objective of developing a resilient system, including with a mobile application, capable of operating under adverse conditions when not all system nodes are available. This will require the implementation of advanced encryption methods to protect sensitive and urgent information exchanges, as well as embedded tracking and monitoring capabilities.This topic contributes to the STEP objectives as defined in the STEP Regulation in the...

Scope:Main battle tanks (MBTs), with their unique combination of protection, mobility and firepower, remain a key element of land military manoeuvre, particularly in the context of conventional warfare. Existing MBT fleets in EU Member States and EDF associated countries are ageing, and new MBT technologies need to be developed and their operational effectiveness in all future scenarios thoroughly tested in order to maintain the current technological edge.This topic therefore aims to follow up and complement previous activities for the development of future MBT systems. These will need to be based on enhanced operational capabilities in all kinds of environments, e.g. in terms of higher multi-spectrum protection and survivability, advanced all-terrain mobility, superior firepower, long-range threat detection and advanced command and control systems, the ability to operate with a reduced...

Scope:The aim of this topic is to follow up and complement previous activities already supported by the EDF in the field of medium-size semi-autonomous surface vessels, with a view to developing a universal fast-moving platform for the specific conditions of the littoral environment, providing enhanced coastal defence capabilities based on different mission modules, but also adaptable to other future naval warfare missions.In particular, this topic aims to review concepts and designs developed and implemented following the EDF call topic EDF-2022-DA-NAVAL-MSAS, while enabling new design, prototyping, testing and qualification activities concerning the platform and its autonomy package, and addressing information/data management and specific mission modules.This topic contributes to the STEP objectives as defined in the STEP Regulation in the target investment area of defence technologies...

Scope:Proposals must demonstrate their disruptive impact on defence applications in order to accelerate the creation and deployment of novel solutions for armed forces and support the uptake of new civilian innovations in the defence sector. Proposals must focus on enhancing operational readiness and effectiveness, improving strategic decision-making and addressing emerging threats through cutting-edge technologies or products. Solutions must embrace disruption to enable armed forces to gain a technological edge and adapt to rapidly evolving security challenges, ultimately ensuring radical technological superiority over potential adversaries. Proposals must address disruptive knowledge, products and technologies in any area of defence interest reaching at least TRL4 .The funded actions should aim to achieve a rapid time-to-market. Management mode: Action implemented in indirect managemen...

Scope:The proposals must demonstrate their disruptive impact on defence applications and address innovative technologies and solutions for defence, including those that can improve the readiness, deployability, reliability, safety and sustainability of forces in defence tasks and missions, for example in terms of operations, equipment, infrastructure, energy solutions, surveillance systems or digital solutions. Proposals must address disruptive knowledge, products and technologies in any area of defence interest (8 ) reaching at least TRL 4 (9 ).In addition, to best complement R&D efforts that already target civil applications and encourage the efficient spinning-in of knowledge, innovation and technological development to the defence sector, this topic also welcomes proposals for add-on research actions to adapt solutions originally developed for civilian applications and previously not...

Scope:The proposals must address innovative defence products, solutions and technologies, including those that can improve readiness, deployability, reliability, safety and sustainability of forces in defence tasks and missions, for example in terms of operations, equipment, infrastructure, energy solutions, surveillance systems or digital solutions.Proposals must address disruptive knowledge, products and technologies in any area of defence interest([1]) from TRL 4 and above([1]).In addition, to best complement R&D efforts that already target civil applications and encourage the efficient spinning-in of knowledge, innovation and technological development to the defence sector, this call topic also welcomes proposals for add-on development actions to adapt solutions originally developed for civil applications and previously not applied in the defence sector.Management mode: Action implem...

Scope:Air-to-air refuelling enhances military operations by enabling long-range missions. Refuelling currently requires manual coordination between tanker operators and receiving pilots, which is complex and labour-intensive. Automated air-to-air refuelling solutions are expected to reduce workload and increase safety for both crews, while also being essential for future unmanned aerial systems.The objective of this topic is to explore the development of sensor systems, in particular hardware and sensor fusion, to enable accurate relative navigation between tanker, receiver and refuelling systems, even in adverse conditions. In addition, enhanced optical sensors, advanced image processing, flight control algorithms and pilot assistance interfaces will play a crucial role in improving the docking and refuelling process, increasing safety and time efficiency.This topic contributes to the S...

Scope:Current military decontamination processes are manual and time-consuming, while automation could improve efficiency, safety and control. Clearance decontamination, which ensures that equipment is safe for transport and disposal, is a challenging process that may require advanced technologies. A new approach to CBRN decontamination is needed that is simple, safe, reliable and uses minimal water. New technologies such as catalysts and UV radiation are being considered to neutralise agents without damaging equipment. Decontamination is also critical in the management of biological emergencies, including epidemics and pandemics, and is not limited to military scenarios. Solid sorbents, including nanosorbents, are promising, with advantages such as low toxicity and non-corrosiveness. Clearance decontamination should conform to nationally established standards and guidelines so that the...