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Expected Outcome: Project results are expected to contribute to all of the following outcomes:Measurable improvements in the status of critical marine and/or freshwaters habitats (including blue carbon sequestration capacities) and of species through active and passive conservation and restoration measures;Increased sustainability of fishing practices and tools and enhanced implementation of eco-system-based approaches as outlined in the Common Fisheries Policy (CFP);Measurable socio-economic benefits for local communities, skill development and job creation;Enhanced governance in the co-management of ecosystems and resources at local and basin level and overall strengthened Mission governance framework;Improved cross-border coordination in fish movement data collection and exchange. Scope:The Communication of the Commission on “A vision for agriculture and food sectors - Shaping togethe...

Expected Outcome:Activities under this topic will support the EU Vision for Agriculture and Food, the EU Soil Strategy for 2030, including the implementation of the EU Soil Monitoring and Resilience Directive, the EU Adaptation Strategy, the EU Water Resilience Strategy, and the forthcoming European Climate Adaptation Plan.Project results are expected to contribute to all the following expected outcomes:enhanced monitoring of soils at subnational level (e.g. regions and municipalities) leading to an overall improved soil resilience against extreme weather events, particularly in terms of soils’ capacity to withstand and recover from floods, droughts, heatwaves and broader temperature fluctuations;tailored soil management practices and solutions that improve soil health are adopted, promoting sustainable land management, enhancing food system resilience, including food security[1], and st...

Expected Outcome:Activities under this topic will help progress towards the objectives and targets of the Mission Soil and of the EU Soil Strategy for 2030, the Zero Pollution Action Plan, the European One Health Action Plan against antimicrobial resistance as well as the Sustainable Development Goals[1].Project results are expected to contribute to all the following expected outcomes:policymakers, land managers and other relevant stakeholders have an enhanced understanding of antimicrobial resistance development in soils, the key drivers and pathways of soil’s contribution to human and animal exposure to antimicrobial resistant genes and organisms, as well as antibiotic biosynthesis in soils;policymakers and land managers have increased access and capacity to implement evidence-based strategies aimed at reducing the risk of antimicrobial resistance development in soils and minimising th...

Expected Outcome:Activities under this topic will help progress towards the objectives and targets of the Mission Soil and the EU Soil Strategy for 2030. Activities should also contribute to the implementation of the Soil Monitoring and Resilience Directive after its adoption.Project results are expected to contribute to all the following expected outcomes:enhanced adoption of impactful sustainable soil management solutions and strategies supported by AI-powered decision support systems by land managers;harmonised, standard, robust, interoperable and accessible methods, protocols and logical architecture for long-term field experiments (LTEs) data collection and integration (including with other datasets) are in place;scientists, policymakers, and land managers gain enhanced access to comprehensive, high-quality soil data, enabling better research, informed decision-making, and effective...

Expected Outcome: Project results are expected to contribute to all of the following outcomes:Harmonized approaches and processes across sites to ensure consistent and simplified access, taking into consideration the sensitivity of marine ecosystems in and around the sites;Accelerated innovation cycles for ocean technologies, shortened time-to-market and reduced costs and risks associated with offshore trials;Availability of cost-efficient at physical testing sites and expertise reducing the need for specialised in-house equipment and competencies;Enhanced ocean technologies ecosystem in support of European leadership in the global market;Provision of cost-efficient access to testing sites and expertise, reducing the need for specialised in-house equipment and competencies. Scope:The development and deployment of innovative ocean technologies for a wide range of applications are paving t...

Expected Outcome:This topic aims at directly engaging and supporting relevant public authorities with mapping at large scale the conditions of marine habitats needed for implementing the Nature Restoration Regulation and for achieving one or several objectives of the Mission Restore our Ocean and Waters[1]. The direct involvement of relevant authorities and stakeholders in the consortium is strongly encouraged.Project results are expected to contribute to all the following expected outcomes: Member States have the capacity and access to tried and tested solutions to complete the mapping of the distribution and condition of coastal and marine habitats listed in Annex II of the Nature Restoration Regulation[2] (NRR) in the waters under their jurisdiction, which is needed to fulfil the obligations under Article 5 of the NRR within the deadlines, and obligations under the Marine Strategy Fra...

Expected Outcome:Activities under this topic will support the objectives of the Mission Soil and contribute to meeting the targets of the EU Soil Strategy for 2030 and the implementation of the Soil Monitoring and Resilience Directive. Furthermore, these activities should advance improvement of soil management and environmental performance outlined in the Vision for Agriculture and Food and the Common Agricultural Policy. Project results are expected to contribute to all the following expected outcomes:enhanced reliability and accessibility of soil health data by and for laboratories, land managers, advisors and policymakers;improved understanding by land managers, other relevant practitioners and policymakers of the conditions, limitations and uncertainties of soil data and outputs and tools (e.g. datasets, indicators, descriptors, methodologies, pedo-transfer functions) developed by Mi...

Expected Outcome:Project results are expected to contribute to all of the following expected outcomes:stakeholders are empowered to implement viable ecosystem restoration measures;competent authorities in charge of implementing the EU Nature Restoration Regulation are able to propose appropriate restoration measures;social, economic and environmental co-benefits and trade-offs of nature restoration activities are demonstrated, including for climate action. Scope:The EU biodiversity strategy for 2030 defines nature restoration objectives in line with target 2 of the Kunming-Montreal Global Biodiversity Framework. The EU Nature Restoration Regulation provides that Member States shall put in place effective and area-based restoration measures. Living labs have the potential to empower a green transition towards nature restoration and climate change mitigation and adaptation by developing so...

Expected Outcome:The Synergy action for Teaming Centres of Excellence (CoE) responds to the need to ensure the sustainability of CoE funded under the Teaming calls[1]. The establishment of CoE in Widening countries, supported by a significant investment in Horizon 2020 and Horizon Europe, has created new opportunities for scientific, societal, and economic impact. However, to fully capitalise on this investment and enhance the sustainability and international competitiveness of these CoE, it is essential to facilitate stronger collaboration and strategic joint initiatives among them.Proposals are expected to contribute to all the following outcomes:Stronger long-term collaboration among Teaming CoE through structured joint initiatives and clustering efforts to enhance mutual learning, resource sharing, and collective research and innovation capacity;Strategic transformation of R&I system...

Expected Outcome:Excellent capacities in research management are essential for institutions and national R&I systems to enhance their research excellence and capitalize on their R&I activities in a knowledge-based economy and society. The Research Management Facility aims at providing institutions in Widening countries that want to establish or upgrade their research management capacities with tailored support. The Research Management Facility also advises on an implementation strategy to introduce changes in the institutional set-up, in line with the ERA priorities. However, the action does not provide support for the implementation of the strategy.Strong research management ensures effective grant acquisition, resource allocation, compliance with funding regulations, and strategic planning. It supports high-quality research by streamlining administrative processes, facilitating interdi...

Expected Outcome:The Hop-on Facility allows for legal entities from Widening countries to join already funded Horizon Pillar II ‘main’ work programme and EIC Pathfinder collaborative R&I actions, subject to the agreement of the respective consortium and provided that legal entities from such countries are not yet participating as beneficiary, associated partner, or affiliated entity. The scheme aims to improve the inclusiveness of Horizon Europe. Selected consortia will be invited to submit a grant agreement amendment request of the eligible already funded action.Project results are expected to contribute to the following outcomes:At system level, mobilise excellence in the Widening countries, increase visibility of the beneficiaries from the widening countries, improve knowledge circulation, and boost their participation in specific thematic domains;At consortium level, open up establis...

Expected Impact:In the short term, the funding is expected to:Increase understanding and dissemination of challenges, risks and good practices in the priority areas identified under this call;Enhance communication, coordination and operational cooperation between authorities responsible for the prevention, detection and repression of corruption;Improve the availability and use of data, methodologies and tools for measuring corruption risks, trends and the impact of anti-corruption measures. Where applicable, proposals should demonstrate how they build on relevant previous or ongoing EU-funded projects and existing corruption measurement frameworks.In the long term, the funding is expected to:Improve the prevention, detection, investigation and prosecution of corruption across the EU;Contribute to the implementation of EU anti-corruption policy priorities, including recommendations addres...

Summary: The fiscal year 2026 (FY26) Alzheimer’s Research Program (AZRP) Transforming Care Award (TrCA) supports clinical research or clinical trials evaluating interventions, innovations, and solutions in critical areas for dementia care for individuals with Alzheimer’s disease and Alzheimer’s disease related dementia (AD/ADRD) and their care partner(s).Distinctive Features:Clinical research and clinical trials are allowed; however, clinical trials solely testing or evaluating pharmacological interventions do not meet the intent of this funding opportunity.Studies utilizing animal models do not meet the intent of the mechanism and are not allowed.Preliminary data are required.Community collaboration is required for research prospectively enrolling human subjects.The AZRP encourages studies to leverage existing cohorts/datasets. Cohorts consisting of individuals 65 years or younger are also encouraged.Career Initiation or Transition (CIT) Partnership Option: The TrCA includes an option for more than one PI and supports both new and existing collaborative partnerships. If recommended for funding, each PI will be named on separate awards to the recipient organization(s). If utilizing this option, at least one independent investigator must meet the CIT Partnership Option eligibility requirements at the time of application submission.

Summary: The fiscal year 2026 (FY26) Alzheimer’s Research Program (AZRP) Transforming Diagnosis Award (TrDA) supports non-incremental, solutions-oriented research that reduces or overcomes important barriers to obtaining a diagnosis, meaningful disease monitoring and accurate prognosis.Distinctive Features:Clinical research is allowed, however clinical trials and animal research are prohibited. Preliminary data are required.Community collaboration is required for studies prospectively enrolling human subjects.Study Population: The AZRP encourages studies to leverage existing cohorts/datasets. Cohorts consisting of individuals 65 years or younger are also encouraged.Career Initiation or Transition (CIT) Partnership Option: The TrDA includes an option for more than one PI and supports both new and existing collaborative partnerships. If recommended for funding, each PI will be named on separate awards to the recipient organization(s). If utilizing this option, at least one independent investigator must meet the CIT Partnership Option eligibility requirements at the time of application submission.

Summary: The fiscal year 2026 (FY26) Alzheimer’s Research Program (AZRP) Transforming Research Award (TrRA) supports non-incremental, robust, well-designed research that drives transformative advancements in reducing risk and preventing the development of Alzheimer’s disease and/or Alzheimer's disease related dementias (AD/ADRD).Distinctive Features:• Applications must address at least one of the following focus areas: ○ Risk Factor Knowledge: Research that advances understanding, identification, and/or validation of risk and/or protective factors, with research outcomes/products focused on accelerating solutions. Projects may include, but are not limited to, research on environmental, epigenetic, genetic, lifestyle, occupational, or other risks not listed here. ○ Risk Reduction Solutions: Research that describes methods, technologies, and strategies that contribute to reducing risk and preventing AD/ADRD.• Clinical research is allowed, however clinical trials and animal research are prohibited.• Preliminary data are required.• Community collaboration is required for research prospectively enrolling human subjects.• Career Initiation or Transition (CIT) Partnership Option: The TrRA includes an option for more than one PI and supports both new and existing collaborative partnerships. If recommended for funding, each PI will be named on separate awards to the recipient organization(s). If utilizing this option, at least one independent investigator must meet

This funding opportunity announcement (FOA) encourages grant applications that support the activities of the National Primate Research Centers (NPRCs). Nonhuman primates (NHPs) are most closely related to humans, both physiologically and genetically. Therefore, NHPs are critical animal models for basic and translational research aimed at understanding human biology, both in normal and diseased states. Proper husbandry and management of NHPs require specialized physical and intellectual resources, which are most effectively and economically provided in centralized primate centers, the resources of which are made available to investigators on a national basis. The NPRCs provide these resources to investigators/grantees who utilize NHPs in biomedical research and thereby complement and help enable the missions of the NIH Institutes and Centers.

The National Heart, Lung, and Blood Institute (NHLBI) Program Project Grant (P01) supports research related to fundamental processes and diseases of the heart, blood and lymphatic vessels, lungs, and blood, including transfusion medicine, blood resources, and sleep disorders other programs including implementation science, health disparities, and translation research that address the mission of the Institute. This FOA requires a minimum of three interrelated research projects that investigate a complex biomedical theme or research question. The projects may be supported by core units, if justified, to facilitate economy of effort, space, and equipment. The NHLBI provides support for Program Project Grants (PPGs) in the belief that collaborative research efforts can accelerate the acquisition of knowledge more effectively than a simple aggregate of research projects that have no interaction or thematic integration. NHLBI is particularly interested in encouraging new scientific directions in PPGs. Use of the P01 activity code is viewed as an opportunity to attract scientists who have not traditionally been supported by the NHLBI. Further, the PPG environment presents an opportunity for emerging scientific leaders to gain insight into how to lead a successful scientific Program, and applicants will have the opportunity to include a project led by an Early Stage Investigator (ESI). All projects in the Program must be interrelated and have objectives that address a central theme within the scientific mandate of the NHLBI.

The goal of the NIGMS Predoctoral Basic Biomedical Sciences Research Training Program is to develop a pool of well-trained scientists available to address the Nations biomedical research agenda. Specifically, this funding opportunity announcement provides support to eligible, domestic institutions to develop and implement effective, evidence-informed approaches to biomedical graduate training and mentoring that will keep pace with the rapid evolution of the biomedical research enterprise. NIGMS expects that the proposed research training programs will incorporate didactic, research, and career development elements to prepare trainees for careers that will have a significant impact on the health-related research needs of the Nation.

Through this funding opportunity announcement (FOA), the National Cancer Institute (NCI) invites applications for P50 Research Center Grants for Specialized Programs of Research Excellence (SPORE). The program will fund P50 SPORE grants to support state-of-the-art investigator-initiated translational research that will contribute to improved prevention, early detection, diagnosis, and treatment of an organ-specific cancer or a highly related group of cancers. For the purpose of this FOA, a group of highly related cancers are those that are derived from the same organ system, such as gastrointestinal, neuroendocrine, head and neck, and other cancers. Other programmatically appropriate groups of cancers may include those centered around a common biological mechanism critical for promoting tumorigenesis and/or cancer progression in organ sites that belong to different organ systems. For example, a SPORE may focus on cancers caused by the same infectious agent or cancers promoted and sustained by dysregulation of a common signaling pathway. In addition, a SPORE may focus on cross-cutting themes such as pediatric cancers or cancer health disparities. The research supported through this program must be translational and must stem from research on human biology using cellular, molecular, structural, biochemical, and/or genetic experimental approaches. SPORE projects must have the goal of reaching a translational human endpoint within the project period of the grant.

The purpose of the Resource-Related Research Projects (R24) grant is to support investigator-initiated resources designed to provide materials and services to support and advance biomedical research on a national basis. An R24 resource grant mechanism is a non-hypothesis-driven activity to provide data, materials, tools, or services that are essential to making timely, high quality, and cost-efficient progress in a field. Hypothesis-driven research applications should not be submitted in response to this program announcement but to another mechanism that encourages this type of research. The resource should be available to any qualified investigator, and should be highly quality controlled, and not duplicate resources available commercially or through other sources. Resources should be designed to provide services to the broad alcohol research community and should not be limited by any specific regional focus.

The Office of Research Infrastructure Programs (ORIP) invites grant applications from core facilities, resource centers, animal vivaria, or individual investigators of other shared resources to systematically study the roles of critical environmental extrinsic factors in biological, behavioral, and treatment studies using animal model species, with the objective of enhancing the rigor and reproducibility of animal research. The research area must be broadly applicable to the scientific interests of two or more NIH Institutes or Centers (ICs) and must evaluate the biological processes that impact multiple organ systems in order to align with the ORIPs NIH-wide mission and programs. The program supports the acquisition or update of modern equipment for measuring, monitoring, recording, and reporting environmental, biological or biobehavioral variables. The equipment requested must be capable of recording and reporting multiple parameters simultaneously.

This Notice of Funding Opportunity (NOFO) invites eligible academic or research institutions to apply for funding support to purchase latest scientific equipment that will enhance and modernize research-supporting operations of existing shared biomedical research facilities. Targeted are laboratory research core facilities, animal research facilities, and other similar shared-use research spaces. The goal of this NOFO is to strengthen research-auxiliary activities of biomedical research facilities and to enhance the efficiency of their operations. The NOFO does not support the purchase of scientific research instruments or their components, nor components of building-level infrastructure equipment that indirectly support research activities.

The specific purpose of this Notice of Funding Opportunity (NOFO) is to promote the development of a diverse, interdisciplinary workforce needed to conduct translational research on Alzheimer's disease and Alzheimer's-related dementias from target discovery through clinical development. This NOFO will support institutional training programs for predoctoral and postdoctoral level researchers with diverse educational backgrounds (i.e., basic biology, translational and clinical research, data science). The program invites eligible institutions to develop interdisciplinary training programs that will provide trainees with the knowledge and skills in data science, disease biology, behavioral research, and traditional and emerging drug discovery disciplines necessary to conduct rigorous and cutting-edge basic, translational, and clinical research for AD/ADRD.

The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH. The overarching goal of this R25 program is to encourage individuals who have not had substantial biomedical research experience, or who have the potential to significantly benefit from additional biomedical research experience to pursue further studies or careers in research. To accomplish the stated over-arching goal, this NOFO will support educational activities with a primary focus on: (1) Research Experiences, (2) Curriculum or Methods Development and (3) Outreach. The NCI’s mission is to conduct and support research, training, health information dissemination, and other programs concerning cancer. This funding opportunity seeks to facilitate educational activities that encourage students to become knowledgeable about cancer and available to focus on cancer later in their careers. To promote broad interest in pursuing a career in biomedical research via early intervention strategies, the NCI Youth Enjoy Science (YES) Program will support efforts to create and maintain an institutional program to engage grades 6-12 and/or undergraduate students in cutting edge cancer research experiences. The proposed institutional programs may also provide research experiences for the grade 6-12 teachers and undergraduate faculty members. The goals are to inspire interest in biomedical sciences, help envision research as a career path, and strengthen practical research and career skills. In alignment with these goals, institutions may develop unique programs that capitalize....

The purpose of the High Impact Specialized Innovation Programs (SIPs) is to support the development and demonstration of unique hub capabilities, research platforms and/or resources to address in a timely manner critical gap areas and/or roadblocks in clinical and translational science at awarded UM1 Clinical and Translational Science Awards (CTSA) Program Hubs (PAR-24-272). Successful programs supported through this funding opportunity are expected to lay a strong foundation for future adoption and/or dissemination of capabilities to additional CTSA Program Hubs.