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Expected Outcome:Project results are expected to contribute to all of the following expected outcomes:increased circularity and reduced emissions of greenhouse gases and air pollutants in the economic sectors, services and product value chains at local and/or regional scale. This also includes an efficient valorisation of local resources, with positive effects on air and water quality as well as on biodiversity;widespread deployment and easier replication, scalability and visibility of circular systemic solutions for a multiplication of their economic, social and environmental benefits;enhanced collaboration and knowledge transfer between public authorities (cities and regions), companies, research and citizens in addressing environmental challenges, such as climate-change, resource depletion and biodiversity loss. Scope:This topic supports the implementation of the European Commission’s...

Expected Outcome:Project results are expected to contribute to all of the following expected outcomes:urban manufacturers significantly increase their resource efficiency through increased circular material use or reduced overall material use per output;urban manufacturers contribute significantly to EU climate, zero pollution, circularity and biodiversity goals by engaging in clean, sustainable and circular business practices;improved knowledge sharing and proliferation of digital tools and methods that facilitate the adoption of circular business practices and enable large-scale diffusion. Scope:The Clean Industrial Deal confirms Europe’s dedication to its decarbonisation goals by offering clear business incentives. It will help create lead markets to boost supply and demand in clean tech and energy-intensive industries (such as chemicals, cement, steel and metals), enabling the decarb...

Expected Outcome:In support to the implementation of the EU Adaptation Strategy, the EU Mission on Adaptation to Climate Change and the EU Preparedness Union Strategy and contributing to the upcoming European Climate Action Plan, project results are expected to improve adaptative capacities of European internal border regional and local authorities, allowing them to jointly address with their neighbours the pressing climate risks.Projects results should contribute to all of the following outcomes:Climate resilience solutions for cross-border risks have been developed and demonstrated. This includes social, governance or nature-based solutions.Regional and local authorities from each side of country borders are better prepared to withstand jointly the impacts of climate change, including systemic risks and cascading effects.National, regional and local authorities are taking on shared res...

Expected Outcome:Proposals under this topic should aim to deliver results that are directed and tailored towards, and contribute to all of the following expected outcomes:Patients afflicted by lung, bowel, breast or prostate cancer[1], will benefit from the outcomes of evidence-based, tailored, innovative, affordable and accessible diagnosis- and treatment-centred clinical research programmes by comprehensive cancer infrastructures[2].Researchers, physicians, patient representatives, civil society, charities, foundations, insurance companies, SMEs and innovators[3] will seize opportunities to respectively co-create, support, upscale or commercialise outcomes of evidence-based, tailored, affordable and accessible clinical research programmes for the diagnosis and treatment of patients afflicted by lung, bowel, breast or prostate cancer.National and regional healthcare providers, healthcar...

Expected Outcome:This action supports the follow-up to the July 2023 Communication on EU Missions assessment[1]. The successful proposal under this topic should aim to deliver results that are directed and tailored towards and contribute to all of the following expected outcomes:Together, a network of registered cancer charities and funding agencies support transnational research and innovation projects on quality of life of children (age range 0-14, age at time of first diagnosis), adolescents (age range 15-19, age at time of first diagnosis) and young adults (age range 20-39, age at time of first diagnosis), cancer patients and survivors using their own financial resources.Projects supported by the network of charities and funding agencies will boost quality of life and long-term outcomes for young cancer patients and survivors, including improved physical, emotional, and social well-b...

Expected Outcome:Proposals under this topic should aim to deliver results that are directed and tailored towards, and contribute to all of the following expected outcomes:People at risk of cancer, cancer patients and their caregivers/families benefit from access to more effective and cost-effective, national or regional, cancer control programmes across EU Member States and Associated Countries.Researchers, physicians, innovators[1], SMEs and other professionals from different disciplines and sectors have access to national, regional or local data on healthcare spending (such as expenditures, resource allocations, organisation and type of healthcare interventions, and for which cancer indications, infrastructure, medical prescriptions, drug pricing, drug sales, reimbursement data from health insurers, population-based cancer registries or other cancer-centred registry data, longitudinal...

Expected Outcome:Activities under this topic will directly progress towards the goal of the Mission Soil to set up 100 living labs and lighthouses to lead the transition to healthy soils by 2030. Activities will also contribute to the goal of the Cancer Mission, i.e.: ‘to improve the lives of more than 3 million people by 2030, through prevention, cure and for those affected by cancer including their families, to live longer and better’. Activities should also contribute to meeting the European Green Deal ambitions and targets and more specifically those of the EU Biodiversity Strategy for 2030, the EU Soil Strategy for 2030, the proposal for a Soil Monitoring and Resilience Directive, the Zero Pollution Action Plan, the Europe's Beating Cancer Plan, the One Health approach, the European Health Data Space, the Chemicals Strategy for Sustainability, the European Chemicals Industry Action...

Expected Outcome:Project results are expected to contribute to all of the following expected outcomes:Measurable improvements in the competitiveness and increased environmental sustainability of the EU’s fisheries and/or aquaculture sectors by integrating circular economy principles;Minimized and better managed waste products derived from fisheries and/or aquaculture sectors as well as improved reutilization and reduction of by-products;Reduced existing barriers preventing the implementation and development of circular principles in seafood chains, such as the cost of advanced processing technologies, regulatory hurdles, lack of collaboration across the different seafood supply chain actors or limited market demand and acceptance;Measurable socio-economic benefits for local stakeholders and communities involved in the seafood processing chain. Scope:Proposals under this topic are expecte...

Expected Outcome:Project results are expected to contribute to all of the following expected outcomes:Increased area and improved condition of marine and coastal vegetated habitats within EU waters through effective on-site conservation, restoration and management of activities to help deliver on the objectives of the Nature Restoration Regulation;Maintained and enhanced capacity of blue carbon ecosystems to naturally store carbon, supporting EU climate mitigation goals;Enhanced capacity of marine vegetated habitats/blue carbon ecosystems to support biodiversity and fisheries;Established novel financing and incentive mechanisms that support conservation, restoration and management of blue forest ecosystems projects;Raised public awareness and improved community participation in blue forest ecosystems protection, restoration and management activities, ensuring long-term involvement. Scope...

Expected Outcome:Proposals under this topic should aim to deliver results that are directed and tailored towards, and contribute to all of the following expected outcomes:Patients with rare or very rare cancers or cancer subtypes have access to tailored, promising biomarker-guided medicines or multi-modal treatment interventions via participation in subsequent clinical trials or national or regional compassionate use programmes by health authorities;Researchers, physicians, innovators[1], startup, spin-off and spin-out companies, SMEs, charities or foundations and other professionals from different disciplines and sectors have access to innovative technology, medical devices or promising biomarker-guided medicines for further validation or commercialisation;National healthcare providers, policymakers and authorities in European regions, EU Member States and Associated Countries have earl...

Expected Outcome:Proposals under this topic should aim to deliver results that are directed and tailored towards and contribute to all of the following expected outcomes:Researchers and health professionals gain a deeper understanding of the functional effects of tumour heterogeneity during cancer initiation and progression, supporting the identification of more precise and novel therapeutic targets. Researchers, health professionals and innovators benefit from improved knowledge and tools to support the discovery and development of next generation genomically-informed cancer treatments.Researchers, innovators, and professionals across disciplines and sectors contribute to the UNCAN.eu research data platform by ensuring data interoperability, and enabling sustainable access to newly developed digital tools and models for the analysis and management of multimodal clinical data. Scope:The...

Expected Outcome:This topic aims at directly engaging and supporting harbour/ports and their communities in demonstrating and accelerating the transitions needed for achieving one or several objectives of the Mission “Restore our Ocean and Waters”. The participation of relevant public bodies managing port authorities and their communities as partners of the consortium is strongly encouraged.Project results are expected to contribute to all of the following expected outcomes:Measurable, quantifiable, verifiable and ambitious progress towards reaching one or several interlinked objectives and targets of the Mission “Restore our Ocean and Waters by 2030”, as set out in the Mission Implementation Plan[1] through implementation of effective and well-managed place-based and people-centred actions;Involvement and increased readiness port cities and authorities for testing, deploying and upscali...

Expected Outcome:AI has the potential to support or facilitate virtually every aspect of regions’ climate adaptation efforts. From risk assessment to climate forecasting, from infrastructure planning to resource management, and more. Contributing to the objectives of the AI Continent Action Plan and the EU Mission on Adaptation to Climate Change, projects are expected to contribute one of the following:AI is used to improve actionable climate adaptation knowledge for European regions and local authorities by integrating climate data into decision-making processes.Specific sectors in the selected regions become more resilient to climate change thanks to the use of AI to improve their processes or technologies, while simultaneously advancing their digital transformation. Scope:RationaleOver the past few years, a rapid and disruptive acceleration of progress in Artificial Intelligence has o...

Expected Outcome:This topic aims at directly engaging with and supporting riparian and coastal areas, waterfront cities and islands and their communities in demonstrating and accelerating the transitions needed for achieving one or several objectives of the Mission “Restore our Ocean and Waters”. The participation of relevant public bodies managing those areas and their communities as partners of the consortium is strongly encouraged.Project results are expected to contribute to all the following outcomes:Member States and Associated Countries are provided with cost-effective and innovative solutions to increasing riparian and coastal areas’ resilience to climate change, especially in waterfront cities and islands, contributing to reach the targets of the EU climate adaptation and water resilience strategies for 2030, but also supporting achievements of the EU biodiversity strategy for 2...

Expected Outcome:Project results are expected to contribute to all of the following expected outcomes:Innovative business models for the development of entrepreneurship and successful local community-driven marine, coastal and freshwater sustainable tourism initiatives;Scalable and economically viable initiatives with the potential to be replicated across multiple sea basins;Enhanced capacity-building and increased engagement of the coastal/river/lake communities and the private sector;Job creation and skills development;Improved marine, coastal and freshwater habitats, biodiversity and enhanced conservation capacity;Increased awareness and behavioural change of tourists and coastal communities towards the conservation of marine and freshwater ecosystems. Scope:The community-driven approach under this topic puts strong emphasis on engaging coastal, riparian and/or lakeside communities as...

Expected Outcome:This topic aims at supporting activities that are enabling or contributing to one or several expected impacts of destination “Developing and using new tools, technologies and digital solutions for a healthy society”. To that end, proposals under this topic should aim to deliver results that are directed at, tailored towards and contributing to all the following expected outcomes:Clinical researchers and developers have access to novel predictive biomarkers to guide a more accurate assessment of disease progression and treatment response and tackle the unmet clinical needs of non-communicable chronic diseases.Clinicians and healthcare professionals use clinically validated predictive biomarkers for implementing more effective clinical research and personalised medicine with better health outcomes in chronic non-communicable diseases.Key stakeholders have access to trustwo...

Expected Outcome:This topic aims at supporting activities that are enabling or contributing to one or several expected impacts of destination “Maintaining an innovative, sustainable, and competitive EU health industry”. To that end, proposals under this topic should aim to deliver results that are directed at, tailored towards and contributing to all the following expected outcomes:Healthcare professionals dispose of diagnostic tools at the point of care that accelerate therapeutic decision making.Patients benefit from fast and accurate diagnosis leading to improved health outcomes.Thanks to more efficient diagnosis, health systems will get better evidence for disease control and prevention strategies. Scope:Point-of-Care (PoC) medical testing has made great technical progress (e.g. improved extraction, microfluidics, miniaturisation, and data processing techniques) with PoC test accurac...

Expected Outcome:Successful proposals should support the recovery, resilience, and EU integration of Ukraine’s forest sector, addressing the compounded impacts of climate change and Russia’s war of aggression.Project results are expected to contribute to all of the following expected outcomes:Ukrainian decision-makers and policymakers gain access to robust scientific data, tools, and methodologies for developing and implementing evidence-based policies that are aligned with EU forest-related policies;recovery, restoration, sustainable management and development of Ukraine’s war-affected forests through improved governance, enhanced institutional capacity, and the implementation of sustainable forest management practices that address the impacts of climate change, biodiversity loss and Russian invasion;strengthened Ukrainian forest research and education systems, providing a solid evidenc...

Expected Outcome:Project results are expected to contribute to all of the following expected outcomes:the capacities and integrated governance of researchers, decision-makers, practitioners, local communities and other stakeholders to effectively collaborate to prevent, eradicate or manage invasive alien species (IAS) are enhanced;native ecosystems are better protected, leading to improved resilience and continuous provision of ecosystem services including for climate mitigation and adaptation. Scope:Invasive alien species are one of the five main direct drivers of biodiversity loss. Besides inflicting major damage to nature and the economy, many invasive alien species also facilitate the outbreak and spread of infectious diseases, posing a threat to humans and native wildlife. The rate of new introductions of invasive alien species has increased in recent years. Without effective contro...

Expected Outcome:Project results are expected to contribute to all of the following expected outcomes:all relevant stakeholders, including consumers, economic and social economy operators and waste managers, have an improved understanding of the technical, environmental, economic and social challenges and benefits to circularity in the footwear industry;economic operators and waste managers are provided with evidence-based, innovative, cost-effective, and scalable solutions that improve the management of end-of-life footwear products, valorise post-consumer footwear waste materials and increase the circularity of the value chain;consumers have access to user-friendly solutions to correctly dispose of end-of-life footwear, thus reducing landfill, improving sustainability practices, supporting them in making more conscious choices, and contributing to climate change mitigation and adaptati...

Expected Outcome:The successful proposal funded under this topic will provide guidelines to industrial operators as well as administrators for contributing to the objectives of the Industrial and Livestock Rearing Emissions Directive, the Clean Industrial Deal and the Zero-pollution Action Plan, addressing technical goals in the scope of the Communication on boosting biotechnology and biomanufacturing in the EU and in the new EU bioeconomy strategy.Project results are expected to contribute to all of the following expected outcomes:innovative circular industrial bio-based systems – including biotechnologies and biomanufacturing – within the EU bioeconomy are deployed to decrease the environmental footprint of industries, not harm biodiversity and address climate neutrality. Scope:Industrial bio-based systems – made by the supply chain of bio-based feedstock and the industrial value chain...

Expected Outcome:Project results are expected to contribute to all the following expected outcomes, driving transformative change for biodiversity and nature positive economic practices:overall, the economic case for biodiversity protection, restoration, sustainable use and the delivery of ecosystem services upon which all life depends, is strengthened including through robust assessments of the cost of inaction;businesses are better able to mainstream biodiversity considerations in decision-making, fostering transformative business models that enhance inclusion for biodiversity, particularly for start-ups and SMEs, including nature-based enterprises[1]. Leveraging synergies in business action on climate to strengthen overall resilience also needs to be considered;policy and decision makers benefit from improved knowledge to drive transformative policy including fiscal reforms to align e...

Expected Outcome:Project results are expected to contribute to all of the following expected outcomes:advancing robust, policy-relevant ecosystem assessment, nature protection and restoration planning activities, and biodiversity trend prediction based on fit for purpose data, thus supporting EU biodiversity and climate objectives;strengthened capacity of researchers, practitioners and decision-makers to improve biodiversity monitoring practices and address knowledge gaps via the integration of data and observations across sensors and platforms, ranging from omics-based data (genomic, transcriptomic, metabolomic), various in-situ to satellite-based Earth observation data;enhanced usability of in-situ datasets as training and validation resources for statistical, machine learning and advanced AI-based approaches, in support of applications such as habitat classification, ecosystem mapping...

Expected Outcome:Project results are expected to contribute to all the following expected outcomes:effective scientific support is provided by the Science Service for Biodiversity to all levels of policymaking related to biodiversity, through the European Commission’s Knowledge Centre for Biodiversity (KCBD); in particular, the coordination of answering ad hoc policy requests related to biodiversity through the mobilisation of the EU-funded scientific community, in collaboration with the KCBD, is expected;enhanced science-policy support and knowledge transfer from EU-funded R&I projects to the Intergovernmental Science-Policy Platform on Biodiversity and Ecosystem Services (IPBES) and the Convention on Biological Diversity (CBD) are ensured;a strengthened, multi-stakeholder knowledge and dialogue platform promotes biodiversity knowledge and the uptake and scaling of nature-based solution...

Expected Outcome:Project results are expected to contribute to all of the following expected outcomes:professionals, consumers and educators adopt innovative repair and refurbishment practices in specific product value chains (electronics, furniture, textiles and footwear), enabling significant reductions in waste, environmental impacts and biodiversity loss, while driving cost savings and job creation in the repair and refurbishment sector;professionals, consumers, local partners, social economy actors and educators have access to high-quality training programs that provide them with technical, business and social skills to repair and refurbish products, thus promoting sustainable consumption and production patterns, climate change adaptation and mitigation, reduction of waste and emissions and enhancing resilience of product value chains. Scope:As the EU strives to reduce waste and pro...