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Expected Outcome:AI has the potential to support or facilitate virtually every aspect of regions’ climate adaptation efforts. From risk assessment to climate forecasting, from infrastructure planning to resource management, and more. Contributing to the objectives of the AI Continent Action Plan and the EU Mission on Adaptation to Climate Change, projects are expected to contribute one of the following:AI is used to improve actionable climate adaptation knowledge for European regions and local authorities by integrating climate data into decision-making processes.Specific sectors in the selected regions become more resilient to climate change thanks to the use of AI to improve their processes or technologies, while simultaneously advancing their digital transformation. Scope:RationaleOver the past few years, a rapid and disruptive acceleration of progress in Artificial Intelligence has o...

Expected Outcome:This topic aims at directly engaging with and supporting riparian and coastal areas, waterfront cities and islands and their communities in demonstrating and accelerating the transitions needed for achieving one or several objectives of the Mission “Restore our Ocean and Waters”. The participation of relevant public bodies managing those areas and their communities as partners of the consortium is strongly encouraged.Project results are expected to contribute to all the following outcomes:Member States and Associated Countries are provided with cost-effective and innovative solutions to increasing riparian and coastal areas’ resilience to climate change, especially in waterfront cities and islands, contributing to reach the targets of the EU climate adaptation and water resilience strategies for 2030, but also supporting achievements of the EU biodiversity strategy for 2...

Expected Outcome:Proposals under this topic should aim to deliver results that are directed and tailored towards, and contribute to all of the following expected outcomes:People at risk of cancer, cancer patients and their caregivers/families benefit from access to more effective and cost-effective, national or regional, cancer control programmes across EU Member States and Associated Countries.Researchers, physicians, innovators[1], SMEs and other professionals from different disciplines and sectors have access to national, regional or local data on healthcare spending (such as expenditures, resource allocations, organisation and type of healthcare interventions, and for which cancer indications, infrastructure, medical prescriptions, drug pricing, drug sales, reimbursement data from health insurers, population-based cancer registries or other cancer-centred registry data, longitudinal...

Expected Outcome:Activities under this topic will directly progress towards the goal of the Mission Soil to set up 100 living labs and lighthouses to lead the transition to healthy soils by 2030. Activities will also contribute to the goal of the Cancer Mission, i.e.: ‘to improve the lives of more than 3 million people by 2030, through prevention, cure and for those affected by cancer including their families, to live longer and better’. Activities should also contribute to meeting the European Green Deal ambitions and targets and more specifically those of the EU Biodiversity Strategy for 2030, the EU Soil Strategy for 2030, the proposal for a Soil Monitoring and Resilience Directive, the Zero Pollution Action Plan, the Europe's Beating Cancer Plan, the One Health approach, the European Health Data Space, the Chemicals Strategy for Sustainability, the European Chemicals Industry Action...

Expected Outcome:This action supports the follow-up to the July 2023 Communication on EU Missions assessment[1]. The successful proposal under this topic should aim to deliver results that are directed and tailored towards and contribute to all of the following expected outcomes:Together, a network of registered cancer charities and funding agencies support transnational research and innovation projects on quality of life of children (age range 0-14, age at time of first diagnosis), adolescents (age range 15-19, age at time of first diagnosis) and young adults (age range 20-39, age at time of first diagnosis), cancer patients and survivors using their own financial resources.Projects supported by the network of charities and funding agencies will boost quality of life and long-term outcomes for young cancer patients and survivors, including improved physical, emotional, and social well-b...

Expected Outcome:Proposals under this topic should aim to deliver results that are directed and tailored towards, and contribute to all of the following expected outcomes:Patients afflicted by lung, bowel, breast or prostate cancer[1], will benefit from the outcomes of evidence-based, tailored, innovative, affordable and accessible diagnosis- and treatment-centred clinical research programmes by comprehensive cancer infrastructures[2].Researchers, physicians, patient representatives, civil society, charities, foundations, insurance companies, SMEs and innovators[3] will seize opportunities to respectively co-create, support, upscale or commercialise outcomes of evidence-based, tailored, affordable and accessible clinical research programmes for the diagnosis and treatment of patients afflicted by lung, bowel, breast or prostate cancer.National and regional healthcare providers, healthcar...

Expected Outcome:Project results are expected to contribute to all of the following expected outcomes:Increased area and improved condition of marine and coastal vegetated habitats within EU waters through effective on-site conservation, restoration and management of activities to help deliver on the objectives of the Nature Restoration Regulation;Maintained and enhanced capacity of blue carbon ecosystems to naturally store carbon, supporting EU climate mitigation goals;Enhanced capacity of marine vegetated habitats/blue carbon ecosystems to support biodiversity and fisheries;Established novel financing and incentive mechanisms that support conservation, restoration and management of blue forest ecosystems projects;Raised public awareness and improved community participation in blue forest ecosystems protection, restoration and management activities, ensuring long-term involvement. Scope...

Expected Outcome:In support to the implementation of the EU Adaptation Strategy, the EU Mission on Adaptation to Climate Change and the EU Preparedness Union Strategy and contributing to the upcoming European Climate Action Plan, project results are expected to improve adaptative capacities of European internal border regional and local authorities, allowing them to jointly address with their neighbours the pressing climate risks.Projects results should contribute to all of the following outcomes:Climate resilience solutions for cross-border risks have been developed and demonstrated. This includes social, governance or nature-based solutions.Regional and local authorities from each side of country borders are better prepared to withstand jointly the impacts of climate change, including systemic risks and cascading effects.National, regional and local authorities are taking on shared res...

Expected Outcome:Project results are expected to contribute to all of the following expected outcomes:Measurable improvements in the competitiveness and increased environmental sustainability of the EU’s fisheries and/or aquaculture sectors by integrating circular economy principles;Minimized and better managed waste products derived from fisheries and/or aquaculture sectors as well as improved reutilization and reduction of by-products;Reduced existing barriers preventing the implementation and development of circular principles in seafood chains, such as the cost of advanced processing technologies, regulatory hurdles, lack of collaboration across the different seafood supply chain actors or limited market demand and acceptance;Measurable socio-economic benefits for local stakeholders and communities involved in the seafood processing chain. Scope:Proposals under this topic are expecte...

Expected Outcome:Proposals under this topic should aim to deliver results that are directed and tailored towards, and contribute to all of the following expected outcomes:Patients with rare or very rare cancers or cancer subtypes have access to tailored, promising biomarker-guided medicines or multi-modal treatment interventions via participation in subsequent clinical trials or national or regional compassionate use programmes by health authorities;Researchers, physicians, innovators[1], startup, spin-off and spin-out companies, SMEs, charities or foundations and other professionals from different disciplines and sectors have access to innovative technology, medical devices or promising biomarker-guided medicines for further validation or commercialisation;National healthcare providers, policymakers and authorities in European regions, EU Member States and Associated Countries have earl...

Expected Outcome:Proposals under this topic should aim to deliver results that are directed and tailored towards and contribute to all of the following expected outcomes:Researchers and health professionals gain a deeper understanding of the functional effects of tumour heterogeneity during cancer initiation and progression, supporting the identification of more precise and novel therapeutic targets. Researchers, health professionals and innovators benefit from improved knowledge and tools to support the discovery and development of next generation genomically-informed cancer treatments.Researchers, innovators, and professionals across disciplines and sectors contribute to the UNCAN.eu research data platform by ensuring data interoperability, and enabling sustainable access to newly developed digital tools and models for the analysis and management of multimodal clinical data. Scope:The...

Expected Outcome:This action supports the follow-up to the July 2023 Communication on EU Missions assessment[1]. Proposals under this topic should aim to deliver results that are directed and tailored towards, and contribute to all of the following expected outcomes:Public procurers, possibly in cooperation with private ones, in the area of cancer-centred healthcare stimulate the competitive development of market-ready, affordable, innovative solutions.The chosen solutions take into consideration the needs of cancer patients living with and beyond cancer through research that supports end-user engagement using participative research models.Procurers create opportunities for European health, technology and medical devices, industrial actors (including start-ups, spin-offs, spin-outs, scale-ups, SMEs) to bring to the market affordable innovations that are cost-efficient, safe and have demo...

Expected Outcome:This topic aims at supporting activities that are enabling or contributing to one or several expected impacts of destination “Maintaining an innovative, sustainable, and competitive EU health industry”. To that end, proposals under this topic should aim to deliver results that are directed at, tailored towards and contributing to all the following expected outcomes:Healthcare professionals dispose of diagnostic tools at the point of care that accelerate therapeutic decision making.Patients benefit from fast and accurate diagnosis leading to improved health outcomes.Thanks to more efficient diagnosis, health systems will get better evidence for disease control and prevention strategies. Scope:Point-of-Care (PoC) medical testing has made great technical progress (e.g. improved extraction, microfluidics, miniaturisation, and data processing techniques) with PoC test accurac...

Expected Outcome:This topic aims at supporting activities that are enabling or contributing to one or several expected impacts of destination “Tackling diseases and reducing disease burden”. To that end, proposals under this topic should aim to deliver results that are directed at, tailored towards and contributing to all the following expected outcomes:Researchers, developers and clinical practitioners have access to state-of-the-art knowledge, data, technologies, tools, methods, best practices, and trainings to develop innovative healthcare interventions aimed at reducing burden of the following specific Non-Communicable Diseases (NCDs): cardiovascular diseases, diabetes, chronic respiratory diseases or chronic kidney diseases.Scientific and clinical communities can use innovative healthcare interventions to generate meaningful advances in clinical practice and care for patients with N...

Expected Outcome:This topic aims at supporting activities that are enabling or contributing to one or several expected impacts of destination “Developing and using new tools, technologies and digital solutions for a healthy society”. To that end, proposals under this topic should aim to deliver results that are directed at, tailored towards and contributing to all the following expected outcomes:Clinical researchers and developers have access to novel predictive biomarkers to guide a more accurate assessment of disease progression and treatment response and tackle the unmet clinical needs of non-communicable chronic diseases.Clinicians and healthcare professionals use clinically validated predictive biomarkers for implementing more effective clinical research and personalised medicine with better health outcomes in chronic non-communicable diseases.Key stakeholders have access to trustwo...

Expected Outcome:Project results are expected to contribute to all of the following expected outcomes:the capacities and integrated governance of researchers, decision-makers, practitioners, local communities and other stakeholders to effectively collaborate to prevent, eradicate or manage invasive alien species (IAS) are enhanced;native ecosystems are better protected, leading to improved resilience and continuous provision of ecosystem services including for climate mitigation and adaptation. Scope:Invasive alien species are one of the five main direct drivers of biodiversity loss. Besides inflicting major damage to nature and the economy, many invasive alien species also facilitate the outbreak and spread of infectious diseases, posing a threat to humans and native wildlife. The rate of new introductions of invasive alien species has increased in recent years. Without effective contro...

Expected Outcome: Project results are expected to contribute to all of the following expected outcomes:land managers, farmers, conservation organizations, researchers, policymakers, and agribusinesses are equipped with the knowledge and tools to implement practices that enhance habitats for farmland birds and mammals, thereby improving pest control, supporting pollination, and strengthening agricultural resilience;challenges, measures, and needs of land managers, farmers and conservation organizations are known and supported via appropriate incentives to facilitate the wide adoption of bird- and mammal-friendly practices. Scope:Maintaining and improving farmland bird populations is crucial for both conservation and the long-term sustainability of food production systems. Farmland birds and mammals provide valuable ecosystem services, such as pest control, pollination, and seed dispersal,...

Expected Outcome:Project results are expected to contribute driving the innovation of public authorities and industrial operators confronted with the Biocidal products regulation (EC) No 528/2012, within the 'safe and sustainable by design' framework. The outcomes should support the goals of the Commission communication on: Building the future with nature: Boosting Biotechnology and Biomanufacturing in the EU, of the EU Startup and Scaleup Strategy, of the Strategy for European Life Sciences and of the new EU bioeconomy strategy.Project results are expected to contribute to all of the following expected outcomes:innovation in bio-based and natural substances brings safer alternatives to hazardous substances contained in biocidal products, with decreased risk on human health and biodiversity, including pollinators;safe, sustainable and effective solutions are developed and tested for the...

Expected Outcome:Project results are expected to contribute to all the following expected outcomes:society and decision-makers are provided with enhanced governance frameworks that integrate knowledge across ecosystems (terrestrial, freshwater and marine) and/or societal challenges, helping overcome institutional barriers, power asymmetries, and policy fragmentation to accelerate transformative change towards a nature positive economy and support EU climate goals;practitioners and public authorities co-create and have access to living labs as innovation hubs for testing, and scaling both governance and socio-economic models that integrate diverse knowledge systems, actively engage stakeholders and support bottom-up and participatory approaches. Scope:As nature positive actions gain momentum and biodiversity is increasingly integrated into policies, it is essential to ensure governance fr...

Expected Outcome: Project results are expected to contribute to all the following expected outcomes:enhanced capacity of private and public stakeholders to increase resource efficiency in collecting, processing and using primary and secondary biomass, ensuring that ecosystems and biodiversity are protected and restored, emissions of greenhouse gases and pollutants reduced, and human needs for biomass satisfied in sufficient and fair way, including food security;increased environmental, social and economic value added from the various uses of biomass, including bio-waste, e.g. food losses and food waste;reduction of greenhouse gas emissions and (air, water and soil) pollution, due to avoiding landfilling and incineration of bio-waste;demonstrated environmental, social and economic and social benefits for the municipalities involved in the collection and provision of bio-waste. Scope:Succe...

Expected Outcome:Project results are expected to contribute to all of the following expected outcomes:activities of protection and restoration of ecosystems by stakeholders become easier and more effective;conditions to scale up the implementation of the EU Nature Restoration Regulation by stakeholders are improved, thus improving ecosystem services including for climate mitigation and adaptation. Scope:Ecosystem restoration strategies for nature restoration and climate change mitigation require a coordinated and coherent set of human interventions and management practices (e.g. temporal protection of plants or removing invasive species, including their seeds) for which there is usually no dedicated mean like specific machinery, equipment or other technical innovations (like for example specific lures for invasive alien species). The most common practice is the use of agricultural machin...

Expected Outcome:Project results are expected to contribute to all of the following expected outcomes:all relevant stakeholders, including consumers, economic and social economy operators and waste managers, have an improved understanding of the technical, environmental, economic and social challenges and benefits to circularity in the footwear industry;economic operators and waste managers are provided with evidence-based, innovative, cost-effective, and scalable solutions that improve the management of end-of-life footwear products, valorise post-consumer footwear waste materials and increase the circularity of the value chain;consumers have access to user-friendly solutions to correctly dispose of end-of-life footwear, thus reducing landfill, improving sustainability practices, supporting them in making more conscious choices, and contributing to climate change mitigation and adaptati...

Expected Outcome:Project results are expected to contribute to all the following expected outcomes, driving transformative change for biodiversity and nature positive economic practices:overall, the economic case for biodiversity protection, restoration, sustainable use and the delivery of ecosystem services upon which all life depends, is strengthened including through robust assessments of the cost of inaction;businesses are better able to mainstream biodiversity considerations in decision-making, fostering transformative business models that enhance inclusion for biodiversity, particularly for start-ups and SMEs, including nature-based enterprises[1]. Leveraging synergies in business action on climate to strengthen overall resilience also needs to be considered;policy and decision makers benefit from improved knowledge to drive transformative policy including fiscal reforms to align e...

Expected Outcome:Project results are expected to contribute to all the following expected outcomes:effective scientific support is provided by the Science Service for Biodiversity to all levels of policymaking related to biodiversity, through the European Commission’s Knowledge Centre for Biodiversity (KCBD); in particular, the coordination of answering ad hoc policy requests related to biodiversity through the mobilisation of the EU-funded scientific community, in collaboration with the KCBD, is expected;enhanced science-policy support and knowledge transfer from EU-funded R&I projects to the Intergovernmental Science-Policy Platform on Biodiversity and Ecosystem Services (IPBES) and the Convention on Biological Diversity (CBD) are ensured;a strengthened, multi-stakeholder knowledge and dialogue platform promotes biodiversity knowledge and the uptake and scaling of nature-based solution...

Expected Outcome:The successful proposal funded under this topic will provide guidelines to industrial operators as well as administrators for contributing to the objectives of the Industrial and Livestock Rearing Emissions Directive, the Clean Industrial Deal and the Zero-pollution Action Plan, addressing technical goals in the scope of the Communication on boosting biotechnology and biomanufacturing in the EU and in the new EU bioeconomy strategy.Project results are expected to contribute to all of the following expected outcomes:innovative circular industrial bio-based systems – including biotechnologies and biomanufacturing – within the EU bioeconomy are deployed to decrease the environmental footprint of industries, not harm biodiversity and address climate neutrality. Scope:Industrial bio-based systems – made by the supply chain of bio-based feedstock and the industrial value chain...