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TheEngineering of Biomedical Systemsprogram is part of the Engineering Biology and Health cluster, which also includes: 1) theBiophotonicsprogram; 2) theBiosensingprogram; 3) theCellular and Biochemical Engineeringprogram; and 4) theDisability and Rehabilitation Engineeringprogram. The goal of theEngineering of Biomedical Systems(EBMS) program is to provide opportunities for fundamental and transformative research projects that integrate engineering and life sciences to solve biomedical problems and serve humanity in the long term. Projects are expected to use an engineering framework (for example, design or modeling) that supports increased understanding of physiological or pathophysiological processes. Projects must include objectives that advance both engineering and biomedical sciences. Projects may include: methods, models, and enabling tools applied to understand or control living systems; fundamental improvements in deriving information from cells, tissues, organs, and organ systems; or new approaches to the design of systems that include both living and non-living components for eventual medical use in the long term. TheEBMS programsupports fundamental and transformative research in the following areas of biomedical engineering: Developmentof validated models (living or computational) of healthy and pathological tissues and organ systems that can support improved fundamental understanding of these systems or that could be applied in the future for development and testing of medical interventions; Designand validation of systems that integrate living and non-living c...

Synopsis TheCellular and Biochemical Engineering(CBE)program is part of theEngineering Biology and Healthcluster, which also includes: 1) theBiophotonicsprogram; 2) theBiosensingprogram; 3) theDisability and Rehabilitation Engineeringprogram; and 4) theEngineering of Biomedical Systemsprogram. TheCellular and Biochemical Engineeringprogram supports fundamental engineering research that advances understanding of cellular andbiomolecular processes. CBE-funded research may lead to the development of enabling technology for advanced biomanufacturing of therapeutic cells, biochemicals, and biopharmaceuticals, and for otherbiotechnology industrie. The program encourages highly innovative and potentially transformative engineering research leading to novel bioprocessing and biomanufacturing approaches. Fundamental to many CBE research projects is the understanding of how biomolecules, subcellular systems, cells, and cell populations interact, and how those interactions lead to changes in structure, function, and behavior. A quantitative treatment of problems related to biological processes is considered vital to successful research projects in the CBE program. Major areas of interest for the program include: Metabolic engineering and synthetic biology for biomanufacturing, The design of synthetic metabolic components and synthetic cells, Microbiome structure, function, maintenance, and design, Protein and enzyme engineering, and Design of integrated chemoenzymatic systems. The CBE program also encourages proposals that effectively integrate knowledge and practices from different d...

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The Catalysis program is part of the Chemical Process Systems cluster, which also includes: 1) the Electrochemical Systems program; 2) the Interfacial Engineering program; and 3) the Process Systems, Reaction Engineering, and Molecular Thermodynamics program. The goals of the Catalysis program are to increase fundamental understanding in catalytic engineering science and to advance the development of catalysts and catalytic reactions that are beneficial to society. Research should focus on critical challenges and opportunities in both new and proven catalysis technologies. Areas of emphasis may include novel catalyst compositions, structures, operating environment, data science tools, theory, and modeling – preferably in various combinations as dictated by the specific reaction and related knowledge and technology gaps. Target applications include fuels, specialty and bulk chemicals, environmental catalysis, biomass conversion to fuels and chemicals, greenhouse gas mitigation, recycling of waste materials, generation of solar hydrogen, as well as efficient routes to energy utilization. Heterogeneous catalysis represents the main thrust of the program. Proposals related to both gas-solid and liquid-solid heterogeneous catalysis are welcome, as are proposals that incorporate concepts from homogeneous catalysis. Recent research trends have highlighted the need for evaluation of catalyst performance and properties under working conditions, especially as supported by advanced in situ and in operando characterization methods. Catalyst synthesizability and stability present additi...

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The Joint Center of Excellence (COE) for Advanced Materials (JAMS) was established in January 2004 to assist in ensuring the safe and reliable application of com­posites and advanced materials to commercial aircraft. The Center is a joint effort of the Center of Excel­lence for Composite and Advanced Materials (CECAM) led by Wich­ita State University and the Center of Excellence for Advanced Mate­rials in Transport Aircraft Struc­tures (AMTAS) led by the Univer­sity of Washington. The COE is a leader in international coordina­tion of research, development, and standardization for structures con­structed from these new materials.The goal of this joint cen­ter is to create a cost-sharing academic, in­dustrial, and governmental part­nership. The members are forging a union between the public sector, the private sector and academic in­stitutions to create a world-class capability to identify solutions for existing and potential advanced materials and structures issues.The focus of this partnership is the research, engineering and de­velopment of information used to assure safety and standardize cer­tification of existing and emerg­ing structural applications of com­posites and advanced materials. Specifically, projects include the evaluation of past applications, performance of applied research and the development of standard engineering practices. This Joint Center of Excellence, working with industry and government, also plays an important role in technology transfer, training, and continuing education for the aircraft industry and regulators.Research Areas:Damage Tolerance o...

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