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The goal of the NHLBI Catalyze Program is to provide a comprehensive suite of support and services to facilitate the transition of basic science discoveries into viable diagnostic and therapeutic candidates that have been cleared for human testing, and to develop translational researchers fluent in product development and entrepreneurship. This specific Catalyze Product Definition initiative will provide the early stage translational support needed for the activities required to develop and test device prototypes, identify diagnostic disease targets and develop associated assays, and develop research tools to treat HLBS diseases and disorders. This is a phased initiative for early stage projects. The R61 phase provides support to identify and test initial prototype designs, to identify a disease target and generate experimental design, and to identify, test and pilot research tools. The R33 phase provides support for continued prototype development and testing, in addition to modifying design features and user feedback, diagnostic product generation, exploration of assay components, and characterization of a load design, and research tool improvement, large trial testing and data integration. Following successful completion of the program, it is expected that the potential products will be poised to move forward for in vivo testing (optimization, safety, efficacy) with additional support from NIH and/or other federal and private programs. This initiative has a companion initiative that supports development of therapeutics and combination products and is also part of a suite...

The goal of the NHLBI Catalyze Program is to provide a comprehensive suite of support and services to facilitate the transition of basic science discoveries into viable diagnostic and therapeutic candidates that have been cleared for human testing, and to develop translational researchers fluent in product development and entrepreneurship. This specific Catalyze Product Definition initiative will provide the early stage translational support needed for prototype testing/design modification, assay development for diagnostic disease targets, and development of research tools for use in the treatment of HLBS diseases and disorders. Following successful completion of the program, it is expected that the potential products will be poised to move forward for in vivo testing (optimization, safety, efficacy) with additional support from NIH and/or other federal and private programs. This initiative has a companion initiative that supports development of therapeutics and combination products and is also part of a suite of innovation grants to advance projects to the point where they can meet the entry criteria for the NHLBI Catalyze Preclinical Program.

Buyer: УНИВЕРСИТЕТСКА МНОГОПРОФИЛНА БОЛНИЦА ЗА АКТИВНО ЛЕЧЕНИЕ - Д-Р ГЕОРГИ СТРАНСКИ ЕАД | Notice type: cn-standard | Procedure: restricted | Contract: supplies | Deadline: 2027-12-23

Buyer: LITGRID, AB | Notice type: cn-standard | Procedure: oth-single | Contract: works | Deadline: 2027-12-23

Buyer: AOK Niedersachsen. Die Gesundheitskasse. | Notice type: cn-standard | Procedure: open | Contract: supplies | Deadline: 2027-12-28

Buyer: AOK Niedersachsen. Die Gesundheitskasse. | Notice type: cn-standard | Procedure: open | Contract: supplies | Deadline: 2027-12-28

Buyer: AOK Niedersachsen. Die Gesundheitskasse. | Notice type: cn-standard | Procedure: open | Contract: supplies | Deadline: 2027-12-28

Buyer: AOK Niedersachsen. Die Gesundheitskasse. | Notice type: cn-standard | Procedure: open | Contract: supplies | Deadline: 2027-12-28

Buyer: AOK Niedersachsen. Die Gesundheitskasse. | Notice type: cn-standard | Procedure: open | Contract: supplies | Deadline: 2027-12-28

Buyer: Pohjois-Pohjanmaan hyvinvointialue | Notice type: cn-social | Procedure: restricted | Contract: services | Deadline: 2027-12-30

Buyer: Elinvoimakeskus sekä työllisyys-, kehittämis- ja hallintokeskus | Notice type: cn-standard | Procedure: restricted | Contract: services | Deadline: 2027-12-30

Buyer: Jyväskylän kaupunki | Notice type: cn-social | Procedure: restricted | Contract: services | Deadline: 2027-12-30

Buyer: Uppsala kommun | Notice type: cn-standard | Procedure: open | Contract: works | Deadline: 2027-12-30

Buyer: Pohjois-Karjalan hankintatoimi | Notice type: cn-standard | Procedure: restricted | Contract: supplies | Deadline: 2027-12-30

Buyer: Pohjois-Pohjanmaan hyvinvointialue | Notice type: cn-social | Procedure: restricted | Contract: services | Deadline: 2027-12-30

Buyer: Hessen Mobil, Straßen- und Verkehrsmanagement, Zentrale | Notice type: cn-standard | Procedure: open | Contract: services | Deadline: 2027-12-30

Buyer: Keski-Suomen hyvinvointialue | Notice type: cn-social | Procedure: restricted | Contract: services | Deadline: 2027-12-30

Buyer: VšĮ Lietuvos nacionalinis radijas ir televizija | Notice type: cn-standard | Procedure: restricted | Contract: supplies | Deadline: 2027-12-30

Buyer: SIVON | Notice type: cn-standard | Procedure: restricted | Contract: services | Deadline: 2027-12-30

Buyer: VšĮ Lietuvos nacionalinis radijas ir televizija | Notice type: cn-standard | Procedure: restricted | Contract: supplies | Deadline: 2027-12-30

Buyer: Pohjois-Pohjanmaan hyvinvointialue | Notice type: cn-social | Procedure: restricted | Contract: services | Deadline: 2027-12-30

Buyer: Elinkeino-, liikenne- ja ympäristökeskusten sekä työ- ja elinkeinotoimistojen kehittämis- ja hallintokeskus | Notice type: cn-standard | Procedure: restricted | Contract: services | Deadline: 2027-12-30

Buyer: Gemeente Rotterdam | Notice type: cn-standard | Procedure: open | Contract: services | Deadline: 2027-12-30

The National Park Service (NPS) are seeking applications for Master Cooperative Agreements from CESU network participants in the following CESU network regions: North and West Alaska Californian Chesapeake Watershed Colorado Plateau Desert Southwest Great Basin Great Lakes Northern Forest Great Plains Great Rivers Gulf Coast Hawaii/Pacific Islands North Atlantic Coast Pacific Northwest Piedmont-South Atlantic Coast Rocky Mountains South Florida Caribbean Southern Appalachian Cooperative agreements to CESU network participants residing in CESU network regions other than those listed above will be pursued separate from this notice of funding opportunity; however, those CESU network participants may still apply for a Master Cooperative Agreement under this announcement.  Application instructions are found in Section D. Application and Submission Information.  Applications will be reviewed and evaluated as they are received and may be submitted at any time up until the closing date of this announcement.  The Cooperative Ecosystem Studies Units network is a national consortium of Federal agencies, tribes, academic institutions, state and local governments, nongovernmental conservation organizations, and other partners working together to support informed public trust resource stewardship. The CESU network includes 390 non-Federal partners and 15 Federal Agencies in seventeen (17) CESUs  representing biogeographic regions encompassing all 50 states and U.S. territories. The CESU network is well positioned as a platform to support research, technical assistance, education and capa...

The Alaska Native Claims Settlement Act (ANCSA) of 1971 included the transfer of 44 million acres to Alaska Native regional and village corporations. Some of these lands became contaminated prior to conveyance (transfer) from a variety of past activities such as fuel storage, power generation, waste handling practices, mining, and other activities. These contaminants can pose health concerns to Alaska Native communities, impact subsistence resources, and impair economic activity. Congress appropriated funding starting in fiscal year 2023 for EPA to establish and implement a grant program to assist Tribal entities in Alaska with addressing contamination on ANCSA lands that were contaminated prior to the time of conveyance. Grants may be used for site assessment and remediation, as well as related community outreach and involvement. Eligible entities include Alaska Native regional and village corporations, federally recognized Tribes in Alaska, Alaska Native nonprofit associations, and inter-tribal consortia comprised of Alaskan tribal entities. Proposals will be accepted on a rolling basis. As long as funds remain available, EPA expects to extend the closing date for this funding opportunity.   Before submitting a proposal, please contact Contaminated ANCSA Assistance Program project managers to indicate interest. Details on how to apply are provided in the Contaminated ANCSA Lands Assistance Program Guidance.