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Awarded activities will facilitate the translation of novel recording and modulation technologies that can be used to treat and/or diagnose central nervous system (CNS) diseases and disorders and to better understand the human CNS, from proof of concept up to the stage of readiness for first in human (FIH) studies. Technologies may incorporate any signal modality (e.g., electrical, optical, magnetic, acoustic) or a combination thereof. Diverse team-based applications that integrate appropriate domains of expertise are encouraged.

The purpose of this Notice of Funding Opportunity (NOFO) is to encourage investigators to pursue translational activities and small clinical studies to advance the development of therapeutic, and diagnostic devices for disorders that affect the nervous or neuromuscular systems. Activities supported in this program include implementation of clinical prototype devices, non-clinical safety and efficacy testing, design verification and validation activities, obtaining an Investigational Device Exemption (IDE) for a Significant Risk (SR) study or Institutional Review Board (IRB) approval for a Non-Significant Risk (NSR) study, as well as a subsequent small clinical study. The clinical study is expected to provide information about the device function or final design that cannot be practically obtained through additional non-clinical assessments (e.g., bench top or animal studies) due to the novelty of the device or its intended use. This NOFO is a milestone-driven cooperative agreement program and will involve participation of NIH program staff in negotiating the final project plan before award and monitoring of research progress.

Quantum Machine Learning

Buyer: Gemeente Amsterdam | Notice type: cn-social | Procedure: open | Contract: services | Deadline: 2027-01-29

Buyer: Vilniaus miesto savivaldybės administracija | Notice type: cn-standard | Procedure: restricted | Contract: supplies | Deadline: 2027-01-29

Buyer: Vilniaus miesto savivaldybės administracija | Notice type: cn-standard | Procedure: restricted | Contract: supplies | Deadline: 2027-01-29

This Notice of Funding Opportunity (NOFO) is issued by the Food and Drug Administration (FDA), Center for Veterinary Medicine (CVM), and solicits Research Project (R01) grant applications from institutions or organizations that propose to develop or support the development of designated new animal drugs intended for minor uses in major species or for use in minor species (MUMS).  The FDA is authorized to provide grants to assist in defraying the costs of qualified safety and effectiveness testing that could be used to satisfy the requirements for FDA approval of MUMS-designated drugs. Only entities developing drugs for veterinary use or parties working as research partners with such entities are eligible for grants. The organization (or applicant) seeking approval of the new animal drug under investigation must have opened an Investigational New Animal Drug (INAD) file with FDA/CVM and must hold a minor use or minor species "designation" granted by FDA/CVM's Office of Minor Use and Minor Species Animal Drug Development (OMUMS) for that drug for a specified intended use, in accordance with the provisions of section 573 of the Food, Drug and Cosmetic Act (21 U.S.C. 360ccc-2) and 21 CFR part 516. FDA/CVM's Office of New Animal Drug Evaluation (ONADE) must have reviewed and concurred with the proposed study protocol before an applicant can submit a grant application.

Buyer: CPAM DE L'ESSONNE | Notice type: cn-standard | Procedure: open | Contract: services | Deadline: 2027-01-31

Buyer: Exploateringskontoret | Notice type: cn-standard | Procedure: oth-mult | Contract: services | Deadline: 2027-01-31

Buyer: AOK PLUS - Die Gesundheitskasse für Sachsen und Thüringen | Notice type: cn-standard | Procedure: open | Contract: supplies | Deadline: 2027-01-31

Buyer: Techniker Krankenkasse | Notice type: cn-standard | Procedure: open | Contract: supplies | Deadline: 2027-01-31

Buyer: AOK Sachsen - Anhalt | Notice type: cn-standard | Procedure: open | Contract: supplies | Deadline: 2027-01-31

Buyer: AOK Sachsen - Anhalt | Notice type: cn-standard | Procedure: open | Contract: supplies | Deadline: 2027-01-31

Buyer: AOK Rheinland-Pfalz/Saarland - Die Gesundheitskasse | Notice type: cn-standard | Procedure: open | Contract: supplies | Deadline: 2027-01-31

Buyer: AOK Rheinland-Pfalz/Saarland - Die Gesundheitskasse | Notice type: cn-standard | Procedure: open | Contract: supplies | Deadline: 2027-01-31

Buyer: AOK Rheinland-Pfalz/Saarland - Die Gesundheitskasse | Notice type: cn-standard | Procedure: open | Contract: supplies | Deadline: 2027-01-31

Buyer: AOK Rheinland-Pfalz/Saarland - Die Gesundheitskasse | Notice type: cn-standard | Procedure: open | Contract: supplies | Deadline: 2027-01-31

Buyer: AOK Rheinland-Pfalz/Saarland - Die Gesundheitskasse | Notice type: cn-standard | Procedure: open | Contract: supplies | Deadline: 2027-01-31

Buyer: AOK PLUS - Die Gesundheitskasse für Sachsen und Thüringen | Notice type: cn-standard | Procedure: open | Contract: supplies | Deadline: 2027-01-31

Buyer: AOK Rheinland-Pfalz/Saarland - Die Gesundheitskasse | Notice type: cn-standard | Procedure: open | Contract: supplies | Deadline: 2027-01-31

Buyer: AOK Rheinland-Pfalz/Saarland - Die Gesundheitskasse | Notice type: cn-standard | Procedure: open | Contract: supplies | Deadline: 2027-01-31

Buyer: Techniker Krankenkasse | Notice type: cn-standard | Procedure: open | Contract: supplies | Deadline: 2027-01-31

Buyer: Techniker Krankenkasse | Notice type: cn-standard | Procedure: open | Contract: supplies | Deadline: 2027-01-31

Buyer: AOK PLUS - Die Gesundheitskasse für Sachsen und Thüringen | Notice type: cn-standard | Procedure: open | Contract: supplies | Deadline: 2027-01-31

Buyer: VĮ Turto bankas | Notice type: cn-standard | Procedure: restricted | Contract: works | Deadline: 2027-01-31