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This Notice of Funding Opportunity Announcement (NOFO) invites grant applications for Environmental Health Sciences Core Centers (EHSCC). As intellectual hubs for environmental health science research, the EHSCC's are expected to be the thought leaders for the field and advance the goals of the 2025-2029 NIEHS Strategic Plan (http://www.niehs.nih.gov/about/strategicplan/). The Core Centers provide critical research infrastructure, shared facilities, services and/or resources, to groups of investigators conducting environmental health sciences research. An EHSCC enables researchers to conduct their independently-funded individual and/or collaborative research projects more efficiently and/or more effectively. The overall goal of an EHSCC is to identify and capitalize on emerging issues that advance improving the understanding of the relationships among environmental exposures, human biology, and disease. The EHSCC supports community engagement and translational research as key approaches to improving public health.

Expected Impact:The action under this topic is expected to achieve the following impacts:Accelerate EU access to more cost-effective interventions in an increasingly ageing population by identifying personalised treatment approaches for elderly-onset immune diseases.Decrease disease risk later in life by defining specific prevention strategies based on ageing biomarkers and risk factors.Halt age-associated disease exacerbation by the identification of predictive and digital biomarkers that can stratify patients for early intervention.Improve quality of life for healthy individuals and patients by preventing further health decline, avoiding escalating care costs, and properly stratifying individuals earlier in the diagnostic pathway.Accelerate adoption of innovative diagnostic, preventative, and therapeutic strategies, strengthening the EU’s position as a healthcare innovator.Evaluate dig...

Expected Impact:The action under this topic is expected to achieve the following impacts:Faster and more informed decision-making through the use of an AI-driven NAM (AI Foundation Toxicology Model) and increased efficiency through rapid processing of vast amounts of data [1].Increased consistency and standardisation in a NAM-based approach, specifically an AI model, used by industry in the efficient development, testing and production of safe and effective innovative health technologies, improving industrial competitiveness.Regulatory adoption of a NAM-enabled second species waiver model (AI Foundation Toxicology Model) and weight-of-evidence framework, in line with recommendations and more consistent global decision-making on waiving second species testing.Reduction in animal use, accelerated timelines and lower costs, enhancing the competitiveness of the European health industry throu...

Expected Impact:The action under this topic is expected to achieve the following impacts and contribute to the following EU policies/initiatives:deliver innovative, early technology solutions that contribute to addressing strategic unmet public health needs across multiple therapy areas to improve prevention, early diagnosis, and treatment;leverage the unique network and scale of IHI JU members to create a pipeline to support innovative startups in the health industry, fully integrated into European initiatives in support of start-ups and entrepreneurship;drive early cross-sector health R&D and innovation to strengthen the European healthcare industry’s global competitiveness, contributing to the EU Industrial Strategy and Pharmaceutical Strategy objectives;create a sustainable network of European healthcare incubators to guide and support highly talented and innovative early-stage compa...

Buyer: AOK Niedersachsen. Die Gesundheitskasse. | Notice type: cn-standard | Procedure: open | Contract: supplies | Deadline: 2027-04-21

Buyer: AOK Niedersachsen. Die Gesundheitskasse. | Notice type: cn-standard | Procedure: open | Contract: supplies | Deadline: 2027-04-21

Buyer: AOK Niedersachsen. Die Gesundheitskasse. | Notice type: cn-standard | Procedure: open | Contract: supplies | Deadline: 2027-04-21

Buyer: ВТОРА СПЕЦИАЛИЗИРАНА АКУШЕРО-ГИНЕКОЛОГИЧНА БОЛНИЦА ЗА АКТИВНО ЛЕЧЕНИЕ-ШЕЙНОВО ЕАД | Notice type: cn-standard | Procedure: restricted | Contract: supplies | Deadline: 2027-04-21

Buyer: Stadt Wolfsburg | Notice type: cn-standard | Procedure: restricted | Contract: supplies | Deadline: 2027-04-22

Buyer: МНОГОПРОФИЛНА БОЛНИЦА ЗА АКТИВНО ЛЕЧЕНИЕ "Д-Р ТОТА ВЕНКОВА" АД | Notice type: cn-standard | Procedure: restricted | Contract: supplies | Deadline: 2027-04-22

Buyer: Ministerstvo investícií, regionálneho rozvoja a informatizácie Slovenskej republiky | Notice type: cn-standard | Procedure: restricted | Contract: supplies | Deadline: 2027-04-23

Buyer: Budapest Gyógyfürdői és Hévizei Zrt. | Notice type: cn-standard | Procedure: oth-mult | Contract: supplies | Deadline: 2027-04-23

Buyer: Viešoji įstaiga CPO LT | Notice type: cn-standard | Procedure: restricted | Contract: supplies | Deadline: 2027-04-23

Buyer: Ministère de la Communauté germanophone de Belgique | Notice type: cn-standard | Procedure: open | Contract: services | Deadline: 2027-04-27

Buyer: AOK Niedersachsen. Die Gesundheitskasse. | Notice type: cn-standard | Procedure: open | Contract: supplies | Deadline: 2027-04-27

Buyer: AOK Niedersachsen. Die Gesundheitskasse. | Notice type: cn-standard | Procedure: open | Contract: supplies | Deadline: 2027-04-27

Buyer: AOK Niedersachsen. Die Gesundheitskasse. | Notice type: cn-standard | Procedure: open | Contract: supplies | Deadline: 2027-04-27

Buyer: AOK Niedersachsen. Die Gesundheitskasse. | Notice type: cn-standard | Procedure: open | Contract: supplies | Deadline: 2027-04-27

Buyer: AOK Niedersachsen. Die Gesundheitskasse. | Notice type: cn-standard | Procedure: open | Contract: supplies | Deadline: 2027-04-27

Buyer: Caisse publique wallonne d'allocations familiales-FAMIWAL | Notice type: cn-standard | Procedure: neg-w-call | Contract: services | Deadline: 2027-04-28

Buyer: Специализирана болница за активно лечение по акушерство и гинекология - Майчин дом ЕАД | Notice type: cn-standard | Procedure: restricted | Contract: supplies | Deadline: 2027-04-28

Buyer: OCAPIAT | Notice type: cn-standard | Procedure: open | Contract: services | Deadline: 2027-04-28

The purpose of the NHLBI Emerging Investigator Award (EIA) is to promote scientific productivity and innovation by providing long-term support and increased flexibility to experienced Program Directors/Principal Investigators (PDs/PIs) who are currently PDs/PIs on at least two NHLBI R01-equivalent awards and whose outstanding record of research demonstrates their ability to make major contributions to heart, lung, blood and sleep (HLBS) research. The EIA is intended to support a research program, rather than a research project, by providing the primary and most likely sole source of NHLBI funding on individual grant awards. The EIA will support the research program of NHLBI-funded investigators for up to seven years. The EIA will provide investigators increased freedom to conduct research that breaks new ground or extends previous discoveries in new directions. It will also allow PDs/PIs to take greater risks and to pursue research that requires a longer timeframe. Research supported by the EIA must be within the scope of the NHLBI mission (http://www.nhlbi.nih.gov/about/org/mission).

The purpose of the NHLBI Outstanding Investigator Award (OIA) is to promote scientific productivity and innovation by providing long-term support and increased flexibility to experienced Program Directors/Principal Investigators (PDs/PIs) who are currently PDs/PIs on at least two NHLBI R01-equivalent awards and whose outstanding record of research demonstrates their ability to make major contributions to heart, lung, blood and sleep (HLBS) research. The OIA is intended to support a research program, rather than a research project, by providing the primary and most likely sole source of NHLBI funding on individual grant awards. The OIA will support the research program of NHLBI-funded investigators for up to seven years. The OIA will provide investigators increased freedom to conduct research that breaks new ground or extends previous discoveries in new directions. It will also allow PDs/PIs to take greater risks and to pursue research that requires a longer timeframe. Research supported by the OIA must be within the scope of the NHLBI mission (https://www.nhlbi.nih.gov/about/mission-statement). It is anticipated that the OIA will: Provide a stable funding environment, thereby improving productivity and facilitating nimble, ambitious, creative research; Accelerate scientific innovation by enabling flexibility in pursuing new research directions as they arise, since PDs/PIs will not be bound to specific aims proposed in advance of the studies; Reduce the time researchers spend writing grant applications and managing multiple grant awards, thereby allowing more time to be devo...

Buyer: Viešoji įstaiga CPO LT | Notice type: cn-standard | Procedure: restricted | Contract: supplies | Deadline: 2027-04-29