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This Notice of Funding Opportunity Announcement (NOFO) intends to supports studies that are both necessary and sufficient to inform the planning of a Phase II-IV clinical trial within NHLBI's mission. The NHLBI expects that applications to this NOFO will describe the planned clinical trial and in so doing demonstrate that the proposed (R34) research is scientifically necessary to design or plan the subsequent trial. Furthermore, this NOFO will support research projects that are designed to provide results that will be sufficient to inform the future trial without further studies. The planned Phase II, III, or IV trial must be primarily intended to test the efficacy, safety, clinical management, or implementation of intervention(s) in the prevention and/or treatment of heart, lung, blood, and sleep disorders. In contrast to the study start up or preparation phase of NHLBI funding opportunities for clinical trials (as described at https://www.nhlbi.nih.gov/grants-and-training/funding-opportunities-and-contacts/clinical-trials-optimization), the R34 mechanism is intended to provide new information that answers a scientific or operational question(s) which may be pragmatic in nature and, therefore, informs the final development of a Phase II-IV clinical trial. Regardless of the results of the R34, support of the proposed future clinical trial will require a new application.

The purpose of this notice of funding opportunity (NOFO) is to support research on interventions to improve health in Native American (NA) populations. This includes 1) etiologic research, where there is a significant gap in knowledge, that will directly inform intervention development or adaptations, 2) research that develops, adapts, or tests the efficacy or effectiveness of health promotion and disease prevention interventions, 3) research that tests culturally informed treatment or recovery interventions and 4) where a sufficient body of knowledge on intervention efficacy exists, research on dissemination and implementation that develops and tests strategies to overcome barriers to the adoption, integration, scale-up, and sustainability of effective interventions. Existing data suggest that significant acute and chronic disease inequities exist for NA populations. Concurrently, NA populations experience unique sociopolitical, historical, and environmental stressors and risks that may exacerbate health conditions and/or impact the effectiveness of existing solutions to address the conditions. They also possess unique strengths and resiliencies that can mitigate stressors or inform intervention strategies. Through this initiative, intervention and related research is sought to build upon community knowledge, resources, and resilience to test science-based, culturally appropriate solutions to reduce morbidity and mortality through identification and remediation of precursors to diseases and disorders and through culturally informed treatment. Interventions should be design...

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Buyer: DRI upravljanje investicij, Družba za razvoj infrastrukture, d.o.o. | Notice type: cn-standard | Procedure: restricted | Contract: services | Deadline: 2027-01-07

The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH. The over-arching goal of this NCI R25 program is to support educational activities that complement and/or enhance the training of a workforce to meet the nations biomedical, behavioral and clinical research needs. To accomplish the stated over-arching goal, this Notice of Funding Opportunity (NOFO) will support creative educational activities with a primary focus on Research Experiences. Applications are encouraged that propose innovative, state-of-the-art programs that address the cause, diagnosis, prevention, or treatment of cancer, rehabilitation from cancer, or the continuing care of cancer patients and the families of cancer patients.

The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH. The over-arching goal of this NCI R25 program is to support educational activities that complement and/or enhance the training of a workforce to meet the nations biomedical, behavioral and clinical research needs. To accomplish the stated over-arching goal, this Notice of Funding Opportunity (NOFO) will support creative educational activities with a primary focus on Curriculum or Methods Development. Applications are encouraged that propose innovative, state-of-the-art programs that address the cause, diagnosis, prevention, or treatment of cancer, rehabilitation from cancer, or the continuing care of cancer patients and the families of cancer patients.

The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH. The over-arching goal of this NCI R25 program is to support educational activities that complement and/or enhance the training of a workforce to meet the nations biomedical, behavioral and clinical research needs. To accomplish the stated over-arching goal, this Notice of Funding Opportunity (NOFO) will support creative educational activities with a primary focus on Courses for Skills Development. Applications are encouraged that propose innovative, state-of-the-art programs that address the cause, diagnosis, prevention, or treatment of cancer, rehabilitation from cancer, or the continuing care of cancer patients and the families of cancer patients.

Buyer: Aufbau- und Entwicklungsgesellschaft Bad Neuenahr-Ahrweiler mbH | Notice type: cn-standard | Procedure: open | Contract: works | Deadline: 2027-01-08

Oceanographic facilities and equipment are supported by the Integrative Programs Section (IPS) of the Division of Ocean Sciences (OCE), Directorate for Geosciences (GEO). These awards are made for the procurement, conversion and/or upgrade, enhancement, or annual operation of platforms in the ocean, coastal and near-shore waters, and Great Lakes. Awards are generally directed specifically to support facilities that lend themselves to shared use within the broad range of Federally supported research and education programs.Most of these platforms and facilities also receive partial support from other federal agencies, state and local governments, and private sources on a proportional basis usually through a daily rate mechanism. The primary objective of these awards is to ensure the availability of appropriate oceanographic facilities for Federally funded investigators and educators. Individual project-based facilities and instrumentation, limited to one, or a small group of, investigator(s), should be supported through appropriate research programs as opposed to through the IPS programs listed herein. The individual programs covered within this solicitation include: 1. Oceanographic Technical Services (Tech Services) 2. Oceanographic Instrumentation (OI) 3. Shipboard Scientific Support Equipment (SSSE) Oceanographic Technical Service (Tech Services): The Tech Services Program provides support of institutional technical services to enhance the scientific productivity of research programs, aboard research vessels and in shore-based, shared-use facilities. Research vessel techn...

The Office of Population Affairs (OPA) announces the anticipated availability of funds for Fiscal Year (FY) 2027 grants under the authority of Title X of the Public Health Service Act, Section 1001 (42 U.S.C. §300).This notice solicits applications for projects to provide Title X services throughout the 50 United States, District of Columbia, Guam, the Commonwealth of Puerto Rico, the Northern Mariana Islands, the U.S. Virgin Islands, American Samoa, the U.S. Outlaying Islands (Midway, Wake, et al.), the Republic of the Marshall Islands, the Federated State of Micronesia, and the Republic of Palau (hereafter, States). OPA intends to make available approximately up to $257 million for up to 90 grant awards for a period of up to five (5) years. The actual amount available will not be determined until enactment of the FY 2027 federal budget.OPA"s Title X Family Planning Program funds "voluntary family planning projects [that] offer a broad range of acceptable and effective family planning methods and services (including natural family planning methods, infertility services, and services for adolescents)." (Title X of the Public Health Service Act, 42 U.S.C. 300 et seq., available at https://opa.hhs.gov/sites/default/files/2020-07/title-x-statute-attachment-a_0.pdf). The Title X Program is implemented through competitively awarded grants to a diverse network of public and private nonprofit entities. The program helps millions of low-income and uninsured Americans develop health literacy and access family planning and related health services, empowering individuals and families....

As part of the Gabriella Miller Kids First Pediatric Research Program (Kids First Program), the NIH invites applications to submit samples from pediatric cohorts for whole genome sequencing at a Kids First Program supported genomic data generating centers. Applicants are encouraged to propose sequencing of existing pediatric cancer or congenital anomaly cohorts to elucidate the genetic contribution (somatic and/or germline) to childhood cancers, to investigate the genetic etiology of congenital anomalies, to study the molecular basis of the associations between congenital anomalies and increased cancer risk, or to expand the range of pediatric disorders included within the Kids First Data Resource. The program will accept applications that propose whole genome, exome, and transcriptome sequencing, as well as clinical-grade sequencing, long-read sequencing, proteomics, and epigenomic assays of tumor or affected tissue, when justified. Applicants are encouraged to propose cohorts to increase representation of existing Kids First Program projects. These data, and associated clinical and phenotypic data, will become part of the Kids First Data Resource Center for sharing with the research community.

Buyer: Comune di Brindisi | Notice type: cn-standard | Contract: services | Deadline: 2027-01-11

Buyer: 57 CHR METZ-THIONVILLE | Notice type: pin-rtl | Contract: supplies | Deadline: 2027-01-11

Buyer: VERIFICACIONES INDUSTRIALES DE ANDALUCÍA, S.A. | Notice type: pin-rtl | Contract: supplies | Deadline: 2027-01-11

Buyer: VERIFICACIONES INDUSTRIALES DE ANDALUCÍA, S.A. | Notice type: pin-rtl | Contract: supplies | Deadline: 2027-01-11

Buyer: VERIFICACIONES INDUSTRIALES DE ANDALUCÍA, S.A. | Notice type: pin-rtl | Contract: services | Deadline: 2027-01-11

Buyer: VERIFICACIONES INDUSTRIALES DE ANDALUCÍA, S.A. | Notice type: pin-rtl | Contract: supplies | Deadline: 2027-01-11

Buyer: Vermögen und Bau Baden-Württemberg, Amt Freiburg | Notice type: cn-standard | Procedure: neg-w-call | Contract: services | Deadline: 2027-01-13

Buyer: УНИВЕРСИТЕТСКА МНОГОПРОФИЛНА БОЛНИЦА ЗА АКТИВНО ЛЕЧЕНИЕ - Д-Р ГЕОРГИ СТРАНСКИ ЕАД | Notice type: cn-standard | Procedure: restricted | Contract: supplies | Deadline: 2027-01-14

This funding opportunity is part of a suite of NOFOs within the NIH HEAL Initiative to support the development of safe, effective, and non-addictive therapeutics to treat pain. The goal is to encourage initial translational efforts that will support a drug discovery program and advance projects to the point where they meet the entry criteria for the Pain Therapeutics Development Program. The scope will therefore be focused on development of assays to support a distinct testing funnel, screening efforts to identify hits, and initial characterization of hits and potential therapeutic agents (including small molecules, biologics, and natural products).

Through this solicitation, the Antarctic Sciences Section (ANT) of the Office of Polar Programs (OPP) funds cutting-edge research that: Improves understanding of interactions among the Antarctic region and global systems. Improves understanding of the dynamic linkages among processes operating in the Antarctic and Southern Ocean and linkages to global Earth systems, which helps inform decision making regarding environmental change. Advances fundamental understanding of Earth systems and the biological, geochemical, and physical processes in the Antarctic and Southern Ocean as drivers and responders to changes on a global scale. Expands fundamental knowledge of Antarctic systems, biota, and processes. Utilizes the unique characteristics of the Antarctic region as a science observing platform. Builds capacity and enhances the US workforce for polar-related science. ANT encourages and supports research that combines disciplinary perspectives and approaches from other fields, research that uses existing data and samples, and other research not requiring a physical presence in Antarctica.This may include projects conducted at locations outside Antarctica that serve as analogues of Antarctic sites or systems. This solicitation does not support projects that would need logistical support from the U.S. Antarctic Program (USAP).Proposers requiring USAP logistical support should consult theAntarctic Sciences web page for current opportunities. Proposers of projects with logistics needs that would be wholly provided by another Antarctic program or organization should contact an ANT Pr...

Buyer: Lietuvos kalėjimų tarnyba | Notice type: cn-standard | Procedure: restricted | Contract: supplies | Deadline: 2027-01-16

Buyer: Bayerische Eisenbahngesellschaft mbH (BEG) | Notice type: cn-standard | Procedure: open | Contract: services | Deadline: 2027-01-18

The National Center for Science and Engineering Statistics (NCSES) of the National Science Foundation (NSF) is one of the thirteen principal federal statistical agencies within the United States. It is responsible for the collection, acquisition, analysis, reporting and dissemination of objective, statistical data related to the science and technology (S&T) enterprise in the United States and other nations that is relevant and useful to practitioners, researchers, policymakers and the public. NCSES uses this information to prepare a number of statistical data reports including Women, Minorities and Persons with Disabilities in Science and Engineering and the National Science Board's biennial report, Science and Engineering (S&E) Indicators. The Center would like to enhance its efforts to support analytic and methodological research in support of its surveys as well as promote the education and training of researchers in the use of large-scale nationally representative datasets. NCSES welcomes efforts by the research community to use NCSES or other data to conduct research on the S&T enterprise, develop improved survey methodologies that could benefit NCSES surveys, explore alternate data sources that could supplement NCSES data, create and improve indicators of S&T activities and resources, strengthen methodologies to analyze S&T statistical data, and explore innovative ways to communicate S&T statistics. To that end, NCSES invites proposals for individual or multi-investigator research projects, doctoral dissertation improvement awards, conferences, experimental research,....

Buyer: Aufbau- und Entwicklungsgesellschaft Bad Neuenahr-Ahrweiler mbH | Notice type: cn-standard | Procedure: open | Contract: works | Deadline: 2027-01-19