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The NSF Trailblazer Engineering Impact Award (TRAILBLAZER) program supports individual investigators who propose novel research projects with the potential to innovatively and creatively address new areas of fundamental or applied research, catalyze development of new industries or capabilities that increase the leadership position for the country, and/or make significant progress towards addressing a national need or grand challenge, particularly in current priority areas including, but not limited to, artificial intelligence (AI), bioengineering, quantum engineering, robotics, and nuclear engineering. TRAILBLAZER will support engineers and scientists who leverage their distinctive track record of innovation and creativity to pursue new research directions that are distinct from their previous or current research areas. All funded TRAILBLAZER projects will form an NSF TRAILBLAZER cohort, and principal investigators will be expected to participate in an annual meeting. TRAILBLAZER investigators may also be invited to additional activities. INFORMATIONAL WEBINAR:The Emerging Frontiers and Multidisciplinary Activities (EFMA) Office will host an informational webinar in early calendar year 2026 to discuss the TRAILBLAZER program and answer questions about the FY 2026 TRAILBLAZER solicitation. Details on how to join this webinar will be posted on theDirectorate for Engineering and EFMA Websites.

DE-FOA-0003548: Unleashing Tribal Energy Development Under this Notice of Funding Opportunity (NOFO), the DOE Office of Indian Energy Policy and Programs is soliciting applications to advance affordable, reliable, and secure energy development of Tribal energy resources for the benefit of Tribes and their members. Projects funded under this NOFO are expected to advance Tribal sovereignty through Tribal energy development, efficiency, and use. Projects under Topic Area 1 are expected to serve the electric loads and support the energy needs of Tribes at the scale of a Tribal community or communities. These projects entail the construction of energy assets and projects. Projects under Topic Area 2 are expected to complete all pre-development activities necessary for the deployment of community scale energy projects. Projects under Topic Area 3 are expected to complete necessary pre-development activities for large scale commercial development of Tribal energy resources which lead to enhancement and strengthening of Tribal energy and economic infrastructure. DOE expects to make approximately $50 million of federal funding available for new awards under this NOFO. DOE may issue awards in one, multiple, or none of the Topic Areas. Please see full notification of funding opportunity at: https://ie-exchange.energy.gov

The Integrated Data Systems and Services (IDSS) program supports operations-level national-scale cyberinfrastructure systems and services that broadly advance and facilitate open, data-intensive and artificial intelligence-driven science and engineering research, innovation, and education. Through this solicitation, the IDSS program is accepting proposals for three categories of projects: Category I. Development, deployment, and operation of novel national-scale integrated data systems and services, which may include interfacing with or leveraging other existing capabilities, systems and services, as appropriate to the project; Category II. Transition of established smaller scale, regional, pilot, or prototype data-focused systems and services to national-scale production/operational quality/level. This may also include enhancement and expansion of existing national-scale data-focused operational systems and services; and Category III. Planning grants for future potential development/deployment or transition/enhancement IDSS projects. NSF and the Office of Advanced Cyberinfrastructure (OAC) have long supported the development of innovative foundational and application-specific cyberinfrastructure resources and systems to address data-intensive research needs at the campus, regional, and community scales, through programs such as Cyberinfrastructure for Sustained Scientific Innovation (CSSI), Campus Cyberinfrastructure (CC*), and other investments. The primary goal of the IDSS program is to support national-scale foundational data cyberinfrastructure that broadly enables dat...

The Biological Anthropology Program seeks to advance scientific knowledge about the processes that have shaped biological diversity in living and fossil humans and their primate relatives through support of basic research on human and primate evolution, biological variation, and interactions between biology, behavior, and culture. The program supports a portfolio of research that demonstrates engagement with biological anthropological and evolutionary theory; includes diverse and interdisciplinary methods in field, laboratory and computational settings; encompasses multiple levels of analysis (e.g., molecular, organismal, population, ecosystem) and time scales from the short-term to evolutionary; and considers the ethical implications and societal impacts of the research. The program also supports a wide range of broader impact activities as part of research grants, including research outcomes with inherent benefit to society, efforts to broaden participation in science, technology, engineering, and mathematics (STEM) research, training and outreach activities and other evidence-based activities developed within the context of the mission, goals, and resources of the organizations and people involved.

Developmental Sciences supports basic research that increases our understanding of perceptual, cognitive, linguistic, social, cultural, and biological processes related to human development across the lifespan. Research supported by this program will add to our knowledge of the underlying developmental processes that support social, cognitive, and behavioral functioning, thereby illuminating ways for individuals to live productive lives as members of society. The Developmental Sciences program supports research that addresses developmental processes within the domains of perceptual, cognitive, social, emotional, language, and motor development across the lifespan by working with any appropriate populations for the topics of interest including infants, children, adolescents, adults (including aging populations), and non-human animals. The program also supports research investigating factors that affect developmental change, including family, peers, school, community, culture, media, physical, genetic, and epigenetic influences. The program funds research that incorporates multidisciplinary, multi-method, and/or longitudinal approaches; develops new methods, models, and theories for studying development; and integrates different processes (e.g., memory, emotion, perception, cognition), levels of analysis (e.g., behavioral, social, neural) and time scales. The program funds basic research that advances our understanding of developmental processes and mechanisms; the program does not fund clinical trials and research focused primarily on health outcomes. The budgets and duratio...

Summary: The fiscal year 2026 (FY26) Peer Reviewed Medical Research Program (PRMRP) Research Advancement Award supports fundamental research studies that will make an important contribution towards research, patient care, and/or quality of life for a disease or condition related to one of the congressionally directed FY26 PRMRP topic areas and one of the FY26 PRMRP portfolio-specific strategic goals.Distinctive Features: Applications must include preliminary data. The Research Advancement Award supports use-inspired basic research to further or validate preliminary findings for short- and long-term impact. Proposed research projects may range from hypothesis testing to expansion of mature data.Funding Details: The Congressionally Directed Medical Research Programs (CDMRP) expects to allot roughly $19.6M to fund approximately 14 Research Advancement Award applications with total cost caps of $1.4M per award. The maximum period of performance is 4 years. It is anticipated that awards made from this FY26 funding opportunity will be funded with FY26 funds, which will expire for use on September 30, 2032. Awards supported with FY26 funds will be made no later than September 30, 2027.

Summary: The fiscal year 2026 (FY26) Peer Reviewed Medical Research Program (PRMRP) Discovery Award supports novel, untested, high-risk, high-reward research projects with the potential to provide new insights, paradigms, technologies, or applications and with a potential to generate preliminary data that will lay the foundation for future projects. The application must address a critical problem or question in the field of research and/or patient care in a congressionally directed FY26 PRMRP topic area and one of the FY26 PRMRP portfolio-specific strategic goals.Distinctive Features: Applications must not include preliminary data. The focus of this award mechanism is innovation. Research proposed to this mechanism should be pioneering and revolutionary, and the outcomes generated by the award are expected to generate robust preliminary data that will lay the groundwork for future avenues of scientific investigation or product development.Funding Details: The Congressionally Directed Medical Research Programs (CDMRP) expects to allot roughly $11.165M to fund approximately 29 Discovery Award applications with total cost caps of $385,000 per award. The maximum period of performance is 2 years. It is anticipated that awards made from this FY26 funding opportunity will be funded with FY26 funds, which will expire for use on September 30, 2032. Awards supported with FY26 funds will be made no later than September 30, 2027.

The U.S. Embassy Kuala Lumpur Public Diplomacy Section seeks proposals that advance American leadership, prosperity, and security interests in Malaysia. This program supports initiatives that promote U.S. technological innovation and economic competitiveness, showcase American excellence in sports and education, strengthen ties with exchange program alumni, and position the United States as Malaysia's most trusted international partner.   Priority areas include: advancing U.S. leadership in artificial intelligence and emerging technologies; leveraging major sporting events to demonstrate American excellence; engaging alumni networks to amplify U.S. influence; and promoting American English language education and pathways to U.S. higher education institutions. Programs should demonstrate clear alignment with U.S. national interests, measurable outcomes, and sustainable impact beyond the grant period. Successful proposals will engage influential Malaysian stakeholders, promote American standards, and contribute to making America more prosperous and secure.

The U.S. Embassy in the Philippines’ Public Diplomacy Section (PDS) of the U.S. Department of State is pleased to announce that we are considering proposals for Public Diplomacy Annual Program Statement (APS) 2026. This APS announcement outlines our funding priorities, the strategic themes we focus on, and the procedures for submitting funding requests. Please read this document carefully and follow all instructions. This notice is subject to availability of funding.

This program element does not have a proposal due date. Proposals may be submitted at any time, pending certain eligibility timing issues related to resubmissions and duplicate proposal avoidance, see the program element text and appropriate overview appendix (e.g., B.1 or C.1). The date shown of 8/1/2026 is the last day that proposals may be submitted subject to the ROSES-25 rules and the current GCAM. The ROSES-26 version of this program element is planned to overlap with this ROSES-25 version by a few weeks, allowing continuous submission of proposals across ROSES years. NOTICE: Amended, January 22, 2026. Table C.2-1: Submission and Review Dates in Section 3.1 has been updated and a new final row with a cutoff date of August 1, 2026, has been added. Also, the expected budget and number of new awards in Section 4 have been increased. New text is in bold and deleted text is struck through. NOTICE: Corrected September 9, 2025. NASEM Astrobiology Strategy citation was corrected to 2019 (see Section 1.1.3), reference to the anonymized Table of Work Effort was added to Section 3.2, and HEC request is not included in anonymized proposal (see Section 3.5). New text is in bold and deleted text is struck through. NOTICE: ROSES-25 Amendment 7 makes the following changes to C.1 the Planetary Research Overview: It establishes funding threshold and submission requirements for substantial instrument or equipment requests (Section 3.11), removes the estimated page limit for pilot studies (Section 3.4) and clarifies text on use of spacecraft mission data (Section 3.5). New text is in bol...

The National Human Genome Research Institute (NHGRI) seeks to broaden the types of knowledge, skills, expertise, experience, and perspectives brought to bear in research addressing the ethical, legal and social implications (ELSI) of advances in human genetics or genomics. This Notice of Funding Opportunity (NOFO) solicits UM1 applications from domestic organizations located in the United States and its territories that received less than $30 million per year in total NIH funding for the past three fiscal years. These organizations are underrepresented among those receiving NHGRI funding for ELSI research. The Building Partnerships and Broadening Perspectives to Advance Ethical, Legal, and Social Implications (ELSI) Research (BPAER) Program will support: 1) transdisciplinary ELSI research addressing timely, complex, and understudied topics, 2) the establishment of research teams that include representatives from relevant communities who are affected by and have an interest in the proposed research, 3) research capacity building to develop, conduct and sustain ELSI research, and 4) workforce development opportunities for early career scholars, research team members, and other research project staff. Transdisciplinary ELSI research projects require involvement from two or more fields of knowledge and use of multiple research approaches. Relevant communities must be actively and meaningfully involved on ELSI research teams across all phases of proposed research projects. Research capacity building plans must be informed by a needs assessment. Given the complex structure, a str...

The U.S. Embassy in Harare, through its Public Diplomacy Section, invites eligible organizations to submit applications to administer the 2026–2027 EducationUSA Opportunity Funds Program (OFP) in Zimbabwe. This program promotes U.S. higher education opportunities for high-achieving Zimbabwean students and helps them overcome the up-front costs of applying to U.S. colleges and universities.The program targets university students seeking either undergraduate or graduate study with U.S. institutions or branch campuses of U.S. colleges and universities.  Participants will be selected based on criteria developed by the Public Diplomacy Section and EducationUSA advisers in Zimbabwe.  The OFP selection committee will also be led by these advisers.The successful organization (the grantee) will receive up to US $54,000 to manage the logistics of two phases of the advising and support process for the 2026–2027 cycle.Phase One involves the grantee covering all required standardized test fees, application fees, certifications, and other approved costs for selected students to enroll to a U.S. higher education program. The grantee will also provide programmatic and logistical support to EducationUSA advisers delivering intensive advising on the U.S. application, financial aid process, online degree programs, and other U.S. accredited alternative education options. The grantee will disburse stipends to regional advisers who support these activities.Phase Two involves managing travel and any pre-departure costs associated with successful students who gain admission and funding to U.S. pro...

The aim of the PAC program is to support empirically grounded, theoretically engaged and methodologically sophisticated research in a wide range of topic areas related to human perceptual, motor, and cognitive processes and their interactions. The PAC program welcomes a wide range of perspectives and a variety of methodologies (including computational modeling if the goal is to expand explanatory theories of human perception, action, or cognition). PAC strongly encourages proposals that examine human behavior in realistic (or real-world) scenarios and that include varied subject population. It is expected that knowledge gained from PAC-supported projects will have a clear and direct path towards benefitting society. PAC is open to co-review of proposals submitted to other programs both within the Social, Behavioral, and Economic Sciences Directorate and across other directorates. Note: Proposals may be returned without review if the primary goal of the research is to understand (1) structure/function mappings between PAC processes and neural activity; (2) clinical populations per se; or (3) behavior of non-human animals without a clear and direct impact on our understanding of human perception, action or cognition. Before submitting a proposal, investigators are encouraged to email sbe-pac@nsf.gov with a one-page summary of the proposed research (modeled after the Project Summary page of a standard proposal and including a description of both Intellectual Merit and Broader Impacts) in order to confirm appropriateness of the work for the PAC program. PIs are strongly encoura...

Synopsis of Program: Science and Technology Studies (STS) is an interdisciplinary field that investigates the conceptual foundations, historical developments and social contexts of science, technology, engineering and mathematics (STEM), including medical science. The STS program supports proposals across a broad spectrum of research that uses historical, philosophical and social scientific methods to investigate STEM theory and practice. STS research may be empirical or conceptual; specifically, it may focus on the intellectual, material or social facets of STEM. Additional Resources SBE Office of Multidisciplinary Activities (SMA) Convergence Accelerator (C-Accel)

The primary aim of the Mathematical Sciences Infrastructure Program is to foster the continuing health of the mathematical sciences research community as a whole. In addition,the program complements the Workforce Program in the Mathematical Sciences in its goal to increase the number of well-prepared U.S. based individuals who successfully pursue careers in the mathematical sciences and in other professions in which expertise in the mathematical sciences plays an increasingly important role. The DMS Infrastructure program invites projects that support core research in the mathematical sciences, including: 1) novel projects supporting research infrastructure across the mathematical sciences community; 2) training projects complementing the Workforce Program, and 3) conference, workshop, and travel support requests that include cross-disciplinary activities or have an impact at the national scale. Proposals under this solicitation submitted to DMS Infrastructure must show engagement in developing or enhancing the mathematical sciences research infrastructure in the U.S., including, but not limited to, broadening participation activities; professional development training; or involvement of students and early career researchers. Proposals must explain the regional or national scale impact of the activity that goes substantially beyond the submitting institution or the location of the event. Full proposals (with exception of conference proposals, which are subject to lead-time requirements) must be submitted close to one of the Full Proposal Target Dates. See below for more inf...

Science of Learning and Augmented Intelligence (SL) supports potentially transformative research that develops basic theoretical insights and fundamental knowledge about principles, processes and mechanisms of learning, and about augmented intelligence — how human cognitive function can be augmented through interactions with others or with technology, or through variations in context. The program supportsresearch addressing learning in individuals and in groups, across a wide range of domains at one or more levels of analysis, including molecular and cellular mechanisms; brain systems; cognitive, affective and behavioral processes; and social and cultural influences. The program also supports research on augmented intelligence that clearly articulates principled ways in which human approaches to learning and related processes, such as in design, complex decision-making and problem-solving, can be improved through interactions with others or through the use of artificial intelligence in technology. These could include ways of using knowledge about human functioning to improve the design of collaborative technologies that have the capacity to learn to adapt to humans. For both aspects of the program, there is special interest in collaborative and collective models of learning and intelligence that are supported by the unprecedented speed and scale of technological connectivity.This includes emphasis on how people and technology working together in new ways and at scale can achieve more than either can attain alone. The program also seeks explanations for how the emergent inte...

This Funding Opportunity Announcement (FOA) encourages joint applications for the Global Infectious Disease (GID) Research Training programs from U.S. and low- and middle-income country (LMIC) institutions. The application should propose a collaborative training program that will strengthen the capacity of a LMIC institution to conduct infectious disease research. FIC will support research-training programs that focus on major endemic or life-threatening emerging infectious diseases, neglected tropical diseases, infections that frequently occur as co-infections in HIV infected individuals or infections associated with non-communicable disease conditions of public health importance in LMICs. Training related to prevention, treatment or public health approaches to any technical area of basic, epidemiology, clinical, behavioral or social science health research may be supported. Research Training programs should incorporate didactic, mentored research and career development skills components to prepare individuals for careers that will have significant impact on the priority health research needs of LMICs. This Funding Opportunity Announcement (FOA) allows support of [trainees] as the lead investigator of an independent clinical trial; or a separate ancillary clinical trial or proposing to gain research experience in a clinical trial led by another investigator, as part of their research and career development.

The Flood Mitigation Assistance (FMA) grant program makes federal funds available to states, U.S. territories, federally recognized tribal governments, and local governments to reduce or eliminate the risk of repetitive flood damage to buildings and structures insured under the National Flood Insurance Program (NFIP) in participating communities. FMA funds a variety of flood mitigation activities that are designed to reduce flood risk to policyholders in an effort to reduce the NFIP’s financial exposure.Applicants can submit applications for this funding opportunity through FEMA Grants Outcomes (GO). Access the system at https://go.fema.gov/

Summary: The fiscal year 2026 (FY26) Peer Reviewed Medical Research Program (PRMRP) Technology/Therapeutic Development Award, a product-driven award mechanism, intends to support the translation of promising preclinical findings into products for clinical applications, including prevention, detection, diagnosis, treatment, or quality of life, for a disease or condition related to one of the congressionally directed FY26 PRMRP topic areas and one of the FY26 PRMRP strategic goals. Products can be tangible items, such as drugs or devices, or can be knowledge products, such as clinical decision-making tools or practice guidelines. Products in development should address or have dual purpose potential for the health care needs of military Service Members, Veterans and their Families.Distinctive Features: For the PRMRP Technology/Therapeutic Development Award, the program expects the research proposed will take an already established proof-of-concept or prototype through the final stages of preclinical development. The PRMRP also expects that the research outcome will be a regulatory filing or translation of findings into clinical practice, as applicable.Funding Details: The Congressionally Directed Medical Research Programs (CDMRP) expects to allot roughly $67.2M to fund approximately 12 Technology/Therapeutic Development Award applications with total cost caps of $5.6M per award. The maximum period of performance is 4 years. It is anticipated that awards made from this FY26 funding opportunity will be funded with FY26 funds, which will expire for use on September 30, 2032. Awar...

Summary: The fiscal year 2026 (FY26) Peer Reviewed Medical Research Program (PRMRP) Lifestyle and Applied Health Research Award supports clinical research and/or clinical trials using a combination of scientific disciplines including occupational science, psychology, psychometrics, biostatistics and epidemiology, surveillance, implementation science, and population health. Applications must address and provide a solution to one of the congressionally directed FY26 PRMRP topic areas and one of the FY26 PRMRP strategic goals.Distinctive Features: This funding opportunity requires patient advocate participation. The patient advocate will be a person living with, or a family member or caretaker of someone with, a disease or condition addressed in one of the congressionally directed FY26 PRMRP topic areas. Animal research is not allowed.Funding Details: The Congressionally Directed Medical Research Programs (CDMRP) expects to allot roughly $16.8M to fund approximately four Lifestyle and Applied Health Research Award applications with total cost caps of $4.2M per award. The maximum period of performance is 4 years. It is anticipated that awards made from this FY26 funding opportunity will be funded with FY26 funds, which will expire for use on September 30, 2032. Awards supported with FY26 funds will be made no later than September 30, 2027.

Summary: The fiscal year 2026 (FY26) Peer Reviewed Medical Research Program (PRMRP) Impact Award supports applied research, defined as use-inspired and practice-oriented science that brings together outcomes from basic research, and insights from the real-world environment, to foster clinical applicability. The Impact Award intends to translate the fundamental understanding of underlying mechanisms toward solutions that have the potential for major near-term impact for patients and clear alignment to one of the congressionally directed FY26 PRMRP topic areas and one of the FY26 PRMRP portfolio-specific strategic goals.Distinctive Features: This funding mechanism allows for multiple Principal Investigators (PIs). Only the initiating PI’s organization will submit a pre-application, but all PIs’ organizations will need to submit full applications. The partnering PI’s application is an abbreviated package specific to their distinct portion of the research project. Be advised, all associated applications for a research project may be withdrawn if the initiating or partnering application is rejected or administratively withdrawn.Funding Details: The Congressionally Directed Medical Research Programs (CDMRP) expects to allot roughly $32.0M to fund approximately 10 Impact Award applications with total cost caps of $2.8M for the Single PI Option, or $3.6M for the Partnering PI Option. The maximum period of performance is 4 years. It is anticipated that awards made from this FY26 funding opportunity will be funded with FY26 funds, which will expire for use on September 30, 2032. Awar...

Summary: The fiscal year 2026 (FY26) Tuberous Sclerosis Complex Research Program (TSCRP) Exploration-Hypothesis Development Award (EHDA) supports the initial exploration of innovative, high-risk, high-gain and potentially groundbreaking concepts in the tuberous sclerosis complex (TSC) research field.Distinctive Features: Preliminary Data is not required. Applications should demonstrate the ability to achieve interpretable results in the absence of preliminary data supporting the hypothesis.

Summary: The fiscal year 2026 (FY26) Tuberous Sclerosis Complex Research Program (TSCRP) Clinical Translational Research Award (CTRA) supports studies that will move promising, well-founded preclinical and/or clinical research findings closer to clinical application, including diagnosis, prognosis or treatment of tuberous sclerosis complex (TSC).Distinctive Features: This funding mechanism allows for multiple Principal Investigators (PIs). Only the initiating PI will submit a pre-application, but all PIs will need to submit full applications. The partnering PI(s) application is an abbreviated package specific to their distinct portion of the research project. Be advised, all associated applications for a research project may be withdrawn if the initiating or partnering application is rejected or administratively withdrawn.

Summary: The fiscal year 2026 (FY26) Tuberous Sclerosis Complex Research Program (TSCRP) Idea Development Award (IDA) supports conceptually innovative and high-impact research that could ultimately lead to critical discoveries in tuberous sclerosis complex (TSC) research and/or improvements in patient care.Distinctive Features: This funding mechanism allows for established and new-to-the-field investigators. New-to-the-field investigators are independent investigators that are early in their faculty appointments and/or established investigators transitioned from other research fields into TSC research. Applications to the New-to-the-Field option will compete separately from the Established Investigators submitting to the regular Idea Development Award (IDA).

PLEASE NOTE: this program has MANDATORY Notices of Intent, which are due via NSPIRES by June 25, 2026. See the full posting on NSPIRES for details. NOTICE: Amended May 8, 2026. This amendment releases final text for this program element, which was previously TBD. Mandatory Notices of Intent are due June 25, 2026, and proposals are due August 6, 2026. This synopsis is a generic summary that is posted for each of the many individual "program elements" in NASA’s Research Opportunities in Space and Earth Sciences (ROSES) – 2025 solicitation. For specific information on this particular program element download and read the PDF of the text of this program element by going to Tables 2 or 3 of ROSES at https://solicitation.nasaprs.com/ROSES2025table2 and https://solicitation.nasaprs.com/ROSES2025table3, respectively, click the title of the program element of interest, a hypertext link will take you to a page for that particular program element. On that page, on the right side under "Announcement Documents" the link on the bottom will be to the PDF of the text of the call for proposals. For example, if one were interested in the Solar System Science program (NNH25ZDA001N-SCUBED) one would follow the link to the NSPIRES page for that program element and then to read the text of the call one would click on “C.2 Solar System Science (.pdf)” to download the text of the call. If one wanted to set it into the context of the goals, objectives and know the default rules for all elements within Appendix C, the planetary science division, one might download and read “C.1 Planetary Science Res...