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NOTICE: Amended May 8, 2026. This amendment releases final text for this program element, which was previously TBD. Notices of Intent are requested by June 25, 2026, and proposals are due August 6, 2026. This synopsis is a generic summary that is posted for each of the many individual "program elements" in NASA’s Research Opportunities in Space and Earth Sciences (ROSES) – 2025 solicitation. For specific information on this particular program element download and read the PDF of the text of this program element by going to Tables 2 or 3 of ROSES at https://solicitation.nasaprs.com/ROSES2025table2 and https://solicitation.nasaprs.com/ROSES2025table3, respectively, click the title of the program element of interest, a hypertext link will take you to a page for that particular program element. On that page, on the right side under "Announcement Documents" the link on the bottom will be to the PDF of the text of the call for proposals. For example, if one were interested in the Solar System Science program (NNH25ZDA001N-SCUBED) one would follow the link to the NSPIRES page for that program element and then to read the text of the call one would click on “C.2 Solar System Science (.pdf)” to download the text of the call. If one wanted to set it into the context of the goals, objectives and know the default rules for all elements within Appendix C, the planetary science division, one might download and read “C.1 Planetary Science Research Program Overview (.pdf)” from that same page. While the letters and numbers are different for each element within ROSES (A.10, B.3, etc.) the b...

The purpose of the Promise Neighborhoods program is to significantly improve the academic and developmental outcomes of children and youth living in the most distressed communities of the United States, including ensuring school readiness, high school graduation, and access to a community-based continuum of high-quality services. The program serves neighborhoods with high concentrations of individuals with low incomes; multiple signs of distress, which may include high rates of poverty, childhood obesity, academic challenges, and juvenile delinquency, adjudication, or incarceration; and adverse childhood experiences; and also serves schools implementing comprehensive support and improvement activities or targeted support and improvement activities under section 1111(d) of the Elementary and Secondary Education Act, as amended (ESEA). All strategies in the continuum of solutions must be accessible to children with disabilities and English learners.

The purpose of theNative American Research Centers for Health (NARCH) program is to fund federally-recognized American Indian/Alaska Native (AI/AN) tribes and tribal organizations to support health-related research, research career enhancement, and research infrastructure enhancement activities.

The Centers of Research Excellence in Science and Technology (CREST) program provides support to enhance the research capabilities of minority-serving institutions (MSIs) as defined in this solicitation’s Eligibility section, through effective integration of education and research. The CREST program, composed of the CREST Centers, the CREST Postdoctoral Research Program, and the projects supported by this CREST-RISE solicitation, promotes the development of new knowledge, enhancements of the research productivity of individual faculty and postdoctoral scholars, and an expanded presence of research doctoral students in science, technology, engineering, and mathematics (STEM) disciplines, especially those from underrepresented groups. CREST-RISE is the component of the CREST program that supports the expansion of institutional research capacity by increasing the strength of institutional graduate programs and the successful production of research doctoral students, especially those from groups underrepresented in STEM. The CREST-RISE component supports STEM research doctoral programs in all NSF supported areas and encourages proposals in areas of national interest, such as artificial intelligence, data science and analytics; advanced materials, manufacturing, robotics; cybersecurity; plant genetics/agricultural technologies; quantum information sciences; nanotechnology, semiconductors/microelectronics technologies; climate change and clean energy. CREST-RISE projects must have a direct connection to the long-term plans of the host department(s) and the institution’s strategic...

The U.S. Department of Agriculture (USDA), Rural Development (RD) Rural Business‐Cooperative Service (RBCS or Agency), requests applications for the Meat and Poultry Processing Expansion Program - Phase 4 (the Program or MPPEP-4) - Fortifying the American Beef Industry. MPPEP-4 is authorized under Section 1001(b)(4) of the American Rescue Plan Act of 2021 (ARPA), which provides funding to make “loans and grants and provide other assistance to maintain and improve food and agricultural supply chain resiliency.” Pursuant to this authority, USDA is making competitive grant funding available to Very Small Processors and Small Processors, and to Intermediate Processors to maximize the value and utilization of their existing capacity, with a focus on promoting local supply chains.   Grant funding in the amount of $60 million is available under this Program. Funding will be divided equally into two separate competitions: one for Very Small Processors and Small Processors, and one for Intermediate Processors. Each competition will have its own ranking and award process. Cost share is required. Applicants will be required to identify sources and amounts that will make up the required cost share in the application and will need to verify cost share funding prior to final award approval. Two types of applications for each of the funding competitions will be accepted:1.      Processing Expansion Projects. Awards will range from $50,000 to $2 million to support a range of activities to increase and diversify processing capacity of American Meat and Poultry, including Equipment-only purc...

Plasma science is a transdisciplinary field of research where fundamental studies in many disciplines, including plasma physics, plasma chemistry, materials science, and space science, come together to advance knowledge for discovery and technological innovation. The primary goal of the ECosystem forLeadingInnovation inPlasmaScience andEngineering (ECLIPSE) program is to identify and capitalize on opportunities for bringing fundamental plasma science investigations to bear on problems of societal and technological need within the scope of science and engineering supported by the participating NSF programs. The ECLIPSE meta-program has been created to foster an inclusive community of scientists and engineers, an ecosystem spanning multiple NSF Directorates, in the pursuit of translational research at the interface of fundamental plasma science and technological innovation. The ECLIPSE program builds on the long history of NSF leadership in supporting multi-disciplinary research in plasma science and engineering, and is intended to enhance organizational unity within NSF, and potentially with other funding agencies, in considering proposals and supporting projects that may otherwise struggle to find a natural home within the existing hierarchy of Directorates, Divisions, and programs within the Foundation. Examples of topical areas within the scope of the ECLIPSE program include but are not limited to: Plasma surface interactions, with applications to, e.g., advanced manufacturing, materials processing, and catalysis. Atmospheric pressure plasmas and microplasmas with applica...

The long-range goal of the Research Training Groups in the Mathematical Sciences (RTG) program is to strengthen the nation's scientific competitiveness by increasing the number of well-prepared U.S. citizens, nationals, and permanent residents who pursue careers in the mathematical sciences, be they in academia, government, or industry. The RTG program supports efforts to improve graduate student research training and professional development through structured groups pursuing collaborative research. In addition to graduate student trainees working with faculty members, RTG supported research teams may, but are not required to, include undergraduate or postdoctoral trainees. The RTG program invites submissions in all fields within mathematical sciences; especially encouraged in 2024-2025 are those that align and integrate research in mathematics and statistics with emerging areas such asArtificial Intelligence, Biotechnology,Quantum Computing, and Cybersecurity.

Correctness for Scientific Computing Systems (CS2) is a joint program of the National Science Foundation (NSF) and the Department of Energy (DOE). The program addresses challenges that are both core to DOE’s mission and essential to NSF’s mission of ensuring broad scientific progress. The program’s overarching goal is to elevate correctness as a fundamental requirement for scientific computing tools and tool chains, spanning low-level libraries through complex multi-physics simulations and emerging scientific workflows. At an elementary level, correctness of a system means that desired behavioral properties will be satisfied during the system’s execution. In the context of scientific computing, correctness can be understood, at both the level of software and hardware, as absence of faulty behaviors such as excessive numerical rounding, floating-point exceptions, data races deadlocks, memory faults, violations of specifications at interfaces of system modules, and so on. The CS2 program puts correctness on an equal footing with performance, the focus of current scientific computing research. This program envisions the necessity of proving correctness even in performant scientific computing systems. Such correctness proofs themselves might rely upon multiple factors, including correctness of static and runtime program analyses. Recognizing that many scientific computing applications are inherently statistical, use probabilistic or randomized algorithms, and/or deal with uncertain data, probabilistic notions of correctness may be needed. It is also critical to realize that cor...

The Established Program to Stimulate Competitive Research (EPSCoR) supports the mission of the U.S. National Science Foundation (NSF) by promoting nationwide scientific progress. Through this program, NSF fosters partnerships among academic institutions, government entities, industry, and non-profits. These collaborations aim to drive long-term improvements in research infrastructure, enhance R&D capacity, and boost the research competitiveness of eligible EPSCoR jurisdictions, including states, territories, and commonwealths. A jurisdiction’s research ecosystem is the interconnected network of institutions, organizations, researchers, trainees, community stakeholders, and resources that contribute to the process of research and innovation that advances fundamental knowledge, generates use-inspired products, and ultimately cultivates beneficial societal impacts for a jurisdiction. E-RISE supports hypothesis-driven or problem-driven research and fosters the development of research teams and products in a scientific topical area that aligns with a jurisdiction’s research ecosystem and priorities, as detailed in the jurisdiction’s Science and Technology (S&T) Plan or drawn from other jurisdiction plans, reports, or publications prepared by appropriate authorities or bodies.E-RISE invitesinnovativeproposalswithin the chosen research area thatwillleadto development and implementation of sustainable broad networks of individuals, institutions, and organizations, and that will transform the science, technology, engineering and mathematics (STEM) research capacity and competitivene...

Summary: The fiscal year 2026 (FY26) Multiple Sclerosis Research Program (MSRP) Clinical Trial Award (CTA) supports the rapid implementation of clinical trials with the potential to have a significant impact on the treatment or management of multiple sclerosis. All applications must address at least one of the FY26 MSRP CTA focus areas. Clinical trials may evaluate promising new products, pharmacologic agents (drugs or biologics), devices, clinical guidance and/or emerging approaches and technologies.Distinctive Features: The FY26 CTA offers two funding levels. The following are generalized descriptions of the scope of research appropriate for each funding level:• Funding Level 1 (CTA-FL1) supports small-scale, proof-of-principle clinical trials (e.g., pilot, first-in-human, phase 0) to demonstrate feasibility or inform the design of more advanced trials, or other clinical trials that are appropriate for this funding level. Preliminary data relevant to the proposed clinical trial are required.• Funding Level 2 (CTA-FL2) supports larger-scale clinical trials at phase 1 or phase 2 that seek to show preliminary evidence of safety or efficacy (i.e., benefit of clinical or paraclinical outcomes) in relevant patient populations. Clear description and justification should be provided, which could include, but is not limited to, the intervention type, trial duration, sample size, outcome measures, assessment tools and frequency of assessment. Preliminary data relevant to the proposed clinical trial in MS populations are required.For the purposes of this funding opportunity, Regulat...

Summary: The fiscal year 2026 (FY26) Multiple Sclerosis Research Program (MSRP) Early Investigator Research Award (EIRA) supports Multiple Sclerosis-focused research opportunities for individuals in the early stages of their careers, under the guidance of one or more designated Mentors. All applications must address at least one of the FY26 MSRP EIRA focus areas.Distinctive Features: This opportunity allows for early-stage investigators to develop a research project, investigate a problem or question in MS research, and further their intellectual development as an MS researcher of the future. All application components for the EIRA are expected to be written by the Principal Investigator (PI), with appropriate direction from the Mentor(s).

Summary: The fiscal year 2026 (FY26) Multiple Sclerosis Research Program (MSRP) Exploration – Hypothesis Development Award (EHDA) supports the initial exploration of innovative, high-risk, high-gain, and potentially groundbreaking concepts in the Multiple Sclerosis (MS) research field. The studies supported by this award mechanism are expected to lay the groundwork for future avenues of scientific investigation. All applications must address at least one of the FY26 MSRP EHDA focus areas. The proposed research project should include a well-formulated, testable hypothesis based on strong scientific rationale and study design. The presentation of preliminary and/or published data is not required.Distinctive Features: This funding mechanism includes two options: Established Investigator and New Investigator. The New Investigator option supports applicants early in their faculty appointments.

Summary: The fiscal year 2026 (FY26) Multiple Sclerosis Research Program (MSRP) Investigator-Initiated Research Award (IIRA) supports highly rigorous, high-impact research projects that have the potential to make an important contribution to Multiple Sclerosis (MS) research, patient care, and/or quality of life. All applications must address at least one of the FY26 MSRP IIRA focus areas. Research projects may focus on any phase of research, excluding clinical trials. The rationale for a research idea may be derived from laboratory discovery, clinical trial results, population-based studies, a clinician’s firsthand knowledge of patients, or anecdotal data. Applications must include preliminary and/or published data that are relevant to MS and the proposed research project.Distinctive Features: This funding mechanism includes two options: Established Investigator or New Investigator. The New Investigator option supports applicants early in their faculty appointments.

Goals and Objectives• Celebrate American Excellence:o Showcase American innovation, technological leadership, and entrepreneurial spirit, celebrating American dynamism or telling America’s story of excellence.o Highlight U.S. achievements in science, technology, sports, industry, and culture.o Demonstrate the excellence and reliability of American products, services, and standards.o Promote American values of free enterprise, individual liberty, and merit-based achievement.• Make America Safero Combat Illegal Immigration: Support programs that address root causes of migration by promoting economic opportunity and security in Bolivia, reducing pressure on U.S. borders.o Counter Transnational Crime: Build Bolivian capacity to combat narcotics trafficking, particularly synthetic drugs and fentanyl precursors, and dismantle criminal networks that threaten U.S. communities.o Enhance Border Security Cooperation: Strengthen information-sharing and law enforcement collaboration between U.S. and Bolivian authorities.o Counter Foreign Anti-American Propaganda and Influence Operations: Expose and counter efforts by adversarial nations to establish strategic footholds that could threaten U.S. interests in the Western Hemisphere.• Make America Strongero Promote Transparency and Anti-Corruption: Support investigative journalism, government accountability mechanisms, and civil society oversight that expose corruption and strengthen democratic institutions aligned with U.S. interests.o Strengthen Rule of Law: Build capacity in judicial and law enforcement institutions to combat crime and u...

TheChemical OceanographyProgram supports research into the chemistry of the oceans and the role of the oceans in global geochemical cycles. Areas of interest include chemical composition, speciation, and transformation; chemical exchanges between the oceans and other components of the Earth system; internal cycling in oceans, seas, and estuaries; and the use of measured chemical distributions as indicators of physical, biological, and geological processes.

The Biological Oceanography Program supports fundamental research in biological oceanography and marine ecologyin environments ranging from estuarine, coastal, and open ocean systems to the deep sea, as well as in the Great Lakes.Proposals submitted to the Program must have a compelling context in population, community, or ecosystem ecology or oceanography, as well as address topics that will contribute significantly to the understanding of marine or Great Lakes ecosystems. The Program supports interdisciplinary research and often co-reviews and co-funds projects with various programs in theDivision of Ocean Sciencesand theDirectorate of Biological Sciences(BIO), among others.Details on research topics funded by the Program, including supplements, RAPIDS, and EAGERS, can be found by selecting the link under Related URLS titled: “Additional Program Information.” To view research projects funded by the Program select the link below titled “What Has Been Funded (Recent Awards Made Through This Program, with Abstracts).”

The Cognitive Neuroscience (CogNeuro) program seeks to fund proposals that can advance our understanding of the neural mechanisms underlying human cognition and behavior. Funded proposals typically relate precise and rich quantifications of physiological responses and behavior in ways that advance theory (Intellectual Merit). Funded proposal also typically strengthen the field through, for example, outreach, mentoring the next generation of diverse cognitive neuroscientists, and/or increasing awareness and utilization of the research the field produces (Broader Impacts). Intellectual Merit In general, successful proposals provide a theoretical motivation and consist of a series of experiments/analyses that test the differential predictions of that theory; they go beyond quantifying physiology during certain tasks and behaviors. Research topics considered for funding include but are not limited to: perception, recognition, categorization, implicit and explicit memory, working memory, attention, language, decision-making, and social reasoning. Commensurate with the inherently multidisciplinary nature of the field and the limitations of any single technique, a wide variety of physiological methods are considered, including but not limited to: neuroimaging (e.g., fMRI, EEG, MEG), non-invasive stimulation (e.g. TMS, tDCS), lesion analysis, intracranial recording, optogenetics, genetics, optical imaging, computational modeling, and pharmacological interventions in both human and non-human primates and other animal models. The program is particularly interested in proposals that a...

The primary objective of the Cultural Anthropology Program is to support fundamental, systematic anthropological research and training to increase understanding of the causes, consequences and complexities of human social and cultural variability. The Cultural Anthropology Program welcomes proposals from researchers in all sub-fields of cultural anthropology and research at any temporal or spatial scale. Methodologies and approaches employed may include ethnographic field research, surveys, remote sensing, the collection of bio-markers, experimental research inside or outside of laboratory settings, archival research, the analysis of materials collections and extant data bases, mathematical and computational modeling and other research tools as appropriate for the proposed research. The overarching research goals should be to produce empirically grounded findings that will be generalizable beyond particular case studies and contribute to building a more robust anthropological science of human society and culture. The U.S. National Science Foundation's mandate is to support basic scientific research. Basic research in cultural anthropology means theory-generating and theory-testing research that creates new knowledge about human culture and society. Therefore, the Cultural Anthropology Program cannot support research that takes as its primary objective improved clinical practice, applied policy or other immediate application. Research that seeks to advance scientific cultural anthropological theories in a way that advances use-inspired objectives may be supported, but the th...

The Physical Oceanography Program supports research on a wide range of topics associated with the structure and movement of the ocean, with the way in which it transports various quantities, with the way the ocean's physical structure interacts with the biological and chemical processes within it, and with interactions between the ocean and the atmosphere, solid earth and ice that surround it.

The Decision, Risk and Management Sciences Program (DRMS) supports scientific research directed at increasing understanding and effectiveness of decision making by individuals, groups, organizations and society. DRMS supports research with solid foundations in theories and methods of the social and behavioral sciences. This social and behavioral science research should advance knowledge, address fundamental scientific and societal issues and have strong broader impacts. DRMS funds disciplinary and interdisciplinary research, doctoral dissertation research improvement grants (DDRIGs) and conferences in the following areas: judgment and decision making; decision analysis and decision aids; risk analysis, perception and communication; societal and public-policy decision making; management science and organizational design. The program supports the use of the RAPID funding mechanism for research that involves ephemeral data, typically tied to disasters or other unanticipated events. Much less frequently, the program also supports highly unusual, proof-of-concept, high-risk projects that are potentially transformational (Early Concept Grants for Exploratory Research – EAGER). For detailed information concerning RAPID and EAGER grants, please review Chapter II.E of theNSF PAPPG. All research must be grounded in theory and generalizable. Purely algorithmic management-science proposals should be submitted to theOperations Engineering (OE)Program rather than to DRMS. Decision, Risk and Management Sciences offers Doctoral Dissertation Research Improvement Grants (DDRIGs) to improve t...

The Decision, Risk and Management Sciences Program (DRMS) supports scientific research directed at increasing understanding and effectiveness of decision making by individuals, groups, organizations and society. DRMS supports research with solid foundations in theories and methods of the social and behavioral sciences. This social and behavioral science research should advance knowledge, address fundamental scientific and societal issues and have strong broader impacts. DRMS funds doctoral dissertation research improvement grants (DDRIGs) in the following areas: Judgement and decision making. Decision analysis and decision aids. Risk analysis, perception and communication. Societal and public-policy decision making. Management science and organizational design. All research must be grounded in theory and generalizable. Purely theoretical or algorithmic proposals are not appropriate for DRMS DDRIG proposals.

The Blueprint Neurotherapeutics Network (BPN) invites applications from neuroscience investigators seeking support to advance their small molecule drug discovery and development projects into the clinic. Participants in the BPN are responsible for conducting all studies that involve disease- or target-specific assays, models, and other research tools and receive funding for all activities to be conducted in their own laboratories. In addition, applicants will collaborate with NIH-funded consultants and can augment their project with NIH contract research organizations (CROs) that specialize in medicinal chemistry, pharmacokinetics, toxicology, formulations development, chemical synthesis including under Good Manufacturing Practices (GMP), and Phase I clinical testing. Projects can enter either at the Discovery stage, to optimize promising hit compounds through medicinal chemistry to the Development stage, to advance a single development candidate through Investigational New Drug (IND)-enabling toxicology studies and phase I clinical testing. Alternatively, projects can enter at the Development stage and progress in a shorter period to IND enabling toxicology studies and phase I clinical testing. BPN awardee Institutions retain their assignment of IP rights and gain assignment of IP rights from the BPN contractors (and thereby control the patent prosecution and licensing negotiations) for drug candidates developed in this program.

The Research Experiences for Undergraduates (REU) program supports active research participation by undergraduate students in any of the areas of research funded by the National Science Foundation. REU projects involve students in meaningful ways in ongoing research programs or in research projects specifically designed for the REU program. This solicitation features two mechanisms for supporting student research: REU Sites are based on independent proposals to initiate and conduct projects that engage a number of students in research. REU Sites may be based in a single discipline or academic department or may offer interdisciplinary or multi-department research opportunities with a coherent intellectual theme. REU Supplements may be included as a component of proposals for new or renewal NSF grants or cooperative agreements or may be requested for ongoing NSF-funded research projects. REU projects with an international dimension are welcome. Undergraduate student participants in either REU Sites or REU Supplements must be U.S. citizens, U.S. nationals,or U.S. permanent residents. Students do not apply to NSF to participate in REU activities, and NSF does not select students for the opportunities. Investigators who receive REU awards establish their own process for receiving and reviewing applications and selecting students, and students follow the instructions provided by each REU Site or REU Supplement to apply. (In some cases, investigators pre-select students for REU Supplements.) To identify appropriate REU Sites, students should consult the directory of active REU Sit...

Summary: This funding mechanism supports interventional research at the individual and/or health care system level which will result in near-term impact on the health-related quality of life of individuals living with lupus. The emphasis is on near-term impact on quality of life. Research must address at least one of the fiscal year 2026 (FY26) Lupus Research Program (LRP) Transformative Vision Award (TVA) focus areas. This mechanism allows for clinical trials but does not allow animal studies.Distinctive Features:• Applications must include preliminary data.• Applications must include at least one lupus consumer advocate as a member of the research team.• This funding mechanism allows for up to three Principal Investigators (PIs). Only the initiating PI will submit a pre-application, but all PIs will need to submit full applications. The partnering PI(s) application is an abbreviated package specific to their distinct portion of the research project. Be advised, all associated applications for a research project may be withdrawn if the initiating or partnering application(s) is rejected or administratively withdrawn.• An individual may be named as PI on only one application per LRP award mechanism (Idea Award, Impact Award, Transformative Vision Development Award, TVA), for a maximum of four applications to the FY26 LRP.

Summary: This funding mechanism supports high-risk/high-reward research that has the potential to make a major impact in lupus research and/or lupus disease. The emphasis is on impact. Research must address at least one of the fiscal year 2026 (FY26) Lupus Research Program (LRP) Impact Award (IPA) focus areas. This funding mechanism does not allow clinical trials.Distinctive Features: The FY26 LRP IPA encourages, but does not require, preliminary data.An individual may be named as Principal Investigator (PI) on only one application per LRP award mechanism (Idea Award, IPA, Transformative Vision Development Award, Transformative Vision Award), for a maximum of four applications to the FY26 LRP.