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The NIH Exploratory/Developmental Grant supports exploratory and developmental research projects by providing support for the early and conceptual stages of these projects. These studies may involve considerable risk but may lead to a breakthrough in a particular area, or to the development of novel techniques, agents, methodologies, models, or applications that could have a major impact on a field of biomedical, behavioral, or clinical research.This Parent Notice of Funding Opportunity is for basic science experimental studies involving humans, referred to in NOT-OD-18-212 as prospective basic science studies involving human participants. These studies fall within the NIH definition of a clinical trial and also meet the definition of basic research. Types of studies that should submit under this FOA include studies that prospectively assign human participants to conditions (i.e., experimentally manipulate independent variables) and that assess biomedical or behavioral outcomes in humans for the purpose of understanding the fundamental aspects of phenomena without specific application towards processes or products in mind. Studies conducted with specific applications toward processes or products in mind should submit under the appropriate Clinical Trials Required or Clinical Trial Optional FOA.The proposed project must be related to the programmatic interests of one or more of the participating NIH Institutes and Centers (ICs) based on their scientific missions

The NIH Research Project Grant supports a discrete, specified, circumscribed project in areas representing the specific interests and competencies of the investigator(s).This Parent Notice of Funding Opportunity is for basic science experimental studies involving humans, referred to in NOT-OD-18-212 as prospective basic science studies involving human participants. These studies fall within the NIH definition of a clinical trial and also meet the definition of basic research. Types of studies that should submit under this NOFO include studies that prospectively assign human participants to conditions (i.e., experimentally manipulate independent variables) and that assess biomedical or behavioral outcomes in humans for the purpose of understanding the fundamental aspects of phenomena without specific application towards processes or products in mind. Studies conducted with specific applications toward processes or products in mind should submit under the appropriate Clinical Trials Required or Clinical Trial Optional NOFO.The proposed project must be related to the programmatic interests of one or more of the participating NIH Institutes and Centers (ICs) based on their scientific missions.

The Stephen I. Katz Early Stage Investigator Research Project Grant supports an innovative project that represents a change in research direction for an early stage investigator (ESI) and for which no preliminary data exist. Applications submitted to this Notice of Funding Opportunity Announcement (NOFO) must not include preliminary data. Applications must include a separate attachment describing the change in research direction. The proposed project must be related to the programmatic interests of one or more of the participating NIH Institutes and Centers (ICs) based on their scientific missions.This Funding Opportunity is for basic science experimental studies involving humans, referred to in NOT-OD-18-212 as prospective basic science studies involving human participants. These studies fall within the NIH definition of a clinical trial and also meet the definition of basic research. Types of studies that should submit under this NOFO include studies that prospectively assign human participants to conditions (i.e., experimentally manipulate independent variables) and that assess biomedical or behavioral outcomes in humans for the purpose of understanding the fundamental aspects of phenomena without specific application towards processes or products in mind. Studies that are NOT conducted with specific applications toward processes or products in mind and which also do not meet the clinical trial definition should submit under the appropriate Clinical Trial Not Allowed NOFO .

The NEI uses UG1 cooperative agreement awards to support investigator-initiated large-scale clinical trials, human gene-transfer, stem cell therapy trials, and other complex or high resource- or safety-risk clinical trials. These projects are multifaceted and of high public health significance requiring clear delineation of study organization including roles and responsibilities and require careful performance oversight and monitoring. For purposes of this Notice of Funding Opportunity (NOFO), the proposed study must be intended to evaluate interventions aimed at screening, diagnosing, preventing, or treating vision disorders, or to compare the effectiveness of two or more established interventions. The NEI UG1-supported studies are typically funded as a group of single-component companion grant awards including the Chairs Grant, the Coordinating Center, and Resource Centers, when appropriate. Specifically, this NOFO encourages applications for the Chair's grant, which includes the scientific rationale, study aims and significance of the research project.

The NEI uses UG1 cooperative agreement awards to support investigator-initiated large-scale clinical trials, human gene-transfer, stem cell therapy trials, and other complex or high resource- or safety-risk clinical trials. These projects are multifaceted and of high public health significance requiring clear delineation of study organization including roles and responsibilities and require careful performance oversight and monitoring. For purposes of this Notice of Funding Opportunity (NOFO), the proposed study must be intended to evaluate interventions aimed at screening, diagnosing, preventing, or treating vision disorders, or to compare the effectiveness of two or more established interventions. The NEI UG1-supported studies are typically funded as a group of single-component companion grant awards including the Chairs Grant, the Coordinating Center, and Resource Centers, when appropriate. Specifically, this NOFO encourages applications for the Coordinating Center grant, which provides details of the Coordinating Center's responsibilities and operations.

The NEI uses UG1 cooperative agreement awards to support investigator-initiated large-scale clinical trials, human gene-transfer, stem cell therapy trials, and other complex or high resource- or safety-risk clinical trials. These projects are multifaceted and of high public health significance requiring clear delineation of study organization including roles and responsibilities and require careful performance oversight and monitoring. For purposes of this Notice of Funding Opportunity (NOFO), the proposed study must be intended to evaluate interventions aimed at screening, diagnosing, preventing, or treating vision disorders, or to compare the effectiveness of two or more established interventions. The NEI UG1-supported studies are typically funded as a group of single-component companion grant awards including the Chairs Grant, the Coordinating Center, and Resource Centers, when appropriate. Specifically, this NOFO encourages applications for the Resource Center grant which provides imaging, laboratory, or other requisite services for a multi-center clinical trial or other complex or high-risk clinical trial.

The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH. The over-arching goal of this NIAAA/NIDA R25 program is to support educational activities that foster a better understanding of biomedical, behavioral, and clinical research on alcohol and other substance use disorders and their implications. To accomplish the stated over-arching goal, this FOA will support creative educational activities with a primary focus on Outreach. Specifically, this FOA will support projects designed to engage practicing health care professionals in education about current and emerging knowledge derived from scientific research on the neurobiology, epidemiology, prevention, and/or treatment of alcohol and other substance use disorders and related health conditions, with the ultimate goal of improving care for individuals who use alcohol and other substances.

The National Institute of Mental Health (NIMH) Division of AIDS Research (DAR) encourages applications for Center Core grants (P30) to support HIV/AIDS Research Centers (ARC). The ARC is intended to provide infrastructure support that facilitates the development of high impact science in HIV/AIDS and mental health that is relevant to the NIMH mission. This Notice of Funding Opportunity (NOFO) intends to support innovative, interdisciplinary research in several areas, including basic, NeuroHIV, behavioral and social, integrated biobehavioral, applied, clinical, translational, and implementation science.

The National Institute of Mental Health (NIMH) Division of AIDS Research (DAR) encourages applications for Center Core grants (P30) to support HIV/AIDS Research Centers (ARC). The ARC is intended to provide infrastructure support that facilitates the development of high impact science in HIV/AIDS and mental health that is relevant to the NIMH mission. This Notice of Funding Opportunity (NOFO) intends to support innovative, interdisciplinary research in several areas, including basic, NeuroHIV, behavioral and social, integrated biobehavioral, applied, clinical, translational, and implementation science.

The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH. The over-arching goal of this National Institute of Mental Health (NIMH) R25 program is to support educational activities that complement and/or enhance the training of a workforce to meet the nations biomedical, behavioral and clinical research needs and advance the priorities outlined in the Office of AIDS Research (OAR) Annual Strategic Plan and the research program priorities of the NIMH Division of AIDS Research (DAR).To accomplish the stated over-arching goal, this NOFO will support creative educational activities with a primary focus on Research Experiences and Mentoring Activities that either capitalize on existing networks of collaborating investigators or develop institute-based research education programs. Both research experiences and mentoring activities are required; research experiences are expected to be primary. Research Education Programs are expected to enhance the professional development of the participants and foster a career trajectory towards independent research in the mental health of HIV/AIDS.

This Notice of Funding Opportunity Announcement (NOFO) solicits resource grant applications for projects that will provide accurate, useful, usable, and understandable health information to populations that experience health disparities and their health care providers. This NOFO supports the development of resources that can be used to improve health and well-being and that lead to reductions in health disparities. Access to accurate, useful, usable, and understandable health information is an important factor when managing health and health care. Proposed projects should harness the capabilities of information technology and medical or health libraries to disseminate clear, evidence-based health-related information in formats used by individuals and their health care providers. Proposed projects should emphasize the development and deployment of new information resources or services, or expand and improve an existing resource or service, to meet the needs of populations experiencing health disparities and to promote health access for all.

The U.S. Department of State’s Embassy in Honduras Public Diplomacy Section (PDS) announces an open competition to implement programs that promote U.S. priorities and strengthen ties between the United States and Honduras. U.S. priorities include advancing regional security, celebrating U.S. excellence tied to the 250th anniversary of U.S. independence, building regional economic prosperity, promoting use of U.S. science, technology, and innovation, and defending freedom of speech. All programs must include an American element, or connection with American expert(s), organization(s), or institution(s) in a specific field that will promote increased understanding of U.S. policy and perspectives.

The Office of Citizen Exchanges in the U.S. Department of State’s Bureau of Educational and Cultural Affairs (ECA) invites proposals for the FY 2026 Leaders Lead On-Demand program (LLOD). This program develops ideas from across the Department of State into customized, two-way exchange projects. LLOD provides rapid response, flexible programming focused on building self-sustaining global, regional, and country-based networks of practitioners.The recipient will design and carry out a series of exchange projects for emerging leaders and mid-level professionals representing government, business, and civil society. The program expects to support approximately four to six exchange projects for approximately 150 participants, including approximately 110 foreign and 40 U.S. participants.Each project will feature a group of foreign participants who will travel to the United States for an intensive, customized program. Activities may include workshops, meetings, or events. Every U.S.-based exchange must also include at least one segment overseas, which should involve U.S. participants. All participants should have relevant experience or expertise in the project’s field. U.S. participants will work with foreign participants during both the U.S. and overseas segments.Please see the amended Notice of Funding Opportunity for additional information.

Expected Outcome:The overall objective of this call for proposals is to ensure around 4 000 placements for mobile jobseekers of all age groups with special focus on young people.The action targets the filling of hard-to-fill vacancies and labour shortages as identified in national/EU labour market studies or other data sources.The action, being strongly result-oriented, contributes to:a) addressing labour market needs, in particular tackling labour markets' imbalances, as well as labour and skills shortages;b) improving the conditions for jobseekers and workers to exercise their right of freedom of movement across the EU;c) filling of hard-to-fill vacancies (in the form of either jobs, traineeships or apprenticeships), notably where specific labour shortages have been identified;d) enhancing the service catalogue of the EURES organisations;e) fostering public-private partnerships within...

Through this Funding Opportunity Announcement (FOA), the National Cancer Institute (NCI) invites applications for investigator-initiated Program Project (P01) applications. The proposed Program may address any of the broad areas of cancer research, including (but not limited to) cancer biology, cancer prevention, cancer diagnosis, cancer treatment, and cancer control. Basic, translational, clinical, and/or population-based studies in all of these research areas are appropriate. Each application submitted in response to this FOA must consist of at least three research projects and an Administrative Core. The projects must share a common central theme, focus, and/or overall objective.

For the addresses for obtaining and submitting an application, please refer to our Common Instructions for Applicants to Department of Education Discretionary Grant Programs, published in the Federal Register on August 29, 2025 (90 FR 42234), and available at https://www.federalregister.gov/documents/2025/08/29/2025-16571/common-instructions-and-information-for-applicants-todepartment-of-education-discretionary-grantams.The purpose of this program is to provide training to interpreters to effectively meet the communication needs of individuals who are deaf or hard of hearing and individuals who are DeafBlind receiving vocational rehabilitation (VR) services and/or services from other programs, such as independent living services, under the Rehabilitation Act of 1973 (Rehabilitation Act).Assistance Listing Number (ALN): 84.160D

The primary objective of the EDMAP component of the National Cooperative Geologic Mapping Program (NCGMP) is to train the next generation of geologic mappers. To do this, the NCGMP provides funds for graduate student and upper-level undergraduate student projects relevant to the creation of geologic maps (defined broadly as maps that characterize the solid Earth and/or its constituents). Through these cooperative agreements, the NCGMP hopes to expand the research and educational capacity of national academic programs that teach Earth science students the broad range of techniques relevant to geologic mapping and the analysis of field, geophysical, borehole, and remote sensing data. As of 2024, EDMAP has funded more than 1,501 students from more than 177 universities. A list of funded FY2025 EDMAP projects can be found in Attachment D of this announcement. For more information about the USGS NCGMP EDMAP Program please visit: EDMAP | U.S. Geological Survey (usgs.gov) or email EDMAP@usgs.gov.

The purpose of this notice is to solicit applications for Safe Streets and Roads for All (SS4A) grants. Funds for the fiscal year (FY) 2026 SS4A grant program are to be awarded on a competitive basis to support planning and demonstration activities, as well as projects and strategies to prevent death and serious injury on roads and streets for all users. Applicants must submit their applications via Valid Eval at: Planning and Demonstration Grants: https://usg.valideval.com/teams/usdot_ss4a_2026_planning_demo/signup Implementation Grants: https://usg.valideval.com/teams/usdot_ss4a_2026_implementation/signup DO NOT SUBMIT APPLICATIONS THROUGH GRANTS.GOV All applications must be submitted by 5:00 PM EDT on Tuesday, May 26, 2026. Applications cannot be submitted into Valid Eval after the deadline. Late applications will not be considered unless there is a technical issue directly caused by the online proposal submission system (Valid Eval), and the applicant contacts Valid Eval at support@valideval.com describing the technical issue no later than 1:00 PM ET on Tuesday, May 26, 2026.

The Office of Sports Diplomacy, in the U.S. Department of State’s Bureau of Educational and Cultural Affairs (ECA), announces an open competition for the FY 2026 Sports Diplomacy On Demand Program. U.S. public and private non-profit organizations meeting the provisions described in Internal Revenue Code section 26 U.S.C. 501(c)(3) may submit proposals to manage short-term sports exchange projects designed to support key sporting and cultural priorities of the Administration.   Sports Diplomacy On Demand (SD On Demand) is a new, flexible program that will allow the Department of State to quickly respond to Administration’s foreign policy priorities in sports. SD On Demand projects are designed for rapid implementation, enabling swift responses to emerging policies, geopolitical opportunities, and pressing foreign policy needs. The SD On Demand Program will advance U.S. foreign policy through sports-focused programs that leverage the Decade of Sport in America, solidifying the FIFA World Cup 2026 legacy, building momentum toward the 2028 Summer Olympic and Paralympic Games in Los Angeles, and beyond.   The recipient will implement a series of customized, short-term sports-based exchange projects for a variety of individuals that may include high-profile athletes, leaders in sports federations and ministries abroad, or non-elite athletes, coaches, and sports administrators. The program expects to support approximately 40 exchange projects for 120-140 participants, including approximately 40-50 foreign participants and 80-90 from the United States. Please see the announcement....

The U.S. Department of State’s Bureau Educational and Cultural Affairs (ECA) announces an open competition to support the FY 2026 America First U.S. Speaker Program. Through this cooperative agreement, ECA will support approximately 580 programs, 360 in-person and 220 virtual, engaging key interlocutors from all regions of the world.   The U.S. Speaker Program is a nimble, rapid response public diplomacy tool that for more than 40 years has built lasting relationships between U.S. citizen experts and foreign decision-makers and other professional interlocutors that serve Administration priorities and the American people.  Programs will focus on America First priorities such as energy security, critical minerals, commercial diplomacy, freedom of expression, digital freedom, and AI. The program recruits experienced American experts from across the United States for in-person and/or virtual exchanges that advance America First priorities. Through the program, American professionals establish and sustain linkages with key foreign audiences and institutions, which directly contribute to economic opportunities for Americans.  The program works with U.S. embassies and consulates to produce impactful in-person programs ranging from three days to three weeks in length; and virtual programs, which can take place on a single date and time and/or may be part of a continuing series.  Programmatic formats include lectures, workshops, seminars, and training series. Please see the announcement for additional information.

The Bureau of Educational and Cultural Affairs (ECA) invite proposals for a cooperative agreement to implement the FY 2026 Kennedy-Lugar Youth Exchange and Study (YES) high school exchange program, hereafter referred to as the YES program. Participants will be on program from approximately January to June 2027. The program requires the following elements:   ·      Manage overseas operations, recruit and select inbound participants, arrange travel, and oversee database and website management for all inbound participants, as well as coordinate the overall program. ·      Manage host family and school placements for inbound foreign participants in the United States, organize “American Excellence” enhancement activities, and provide ongoing monitoring and support.   Although not required, applicants have the option to also propose a YES Abroad outbound component, recruiting, placing, and monitoring up to 30 American students who will attend high school and live with host families overseas.      The YES program advances U.S. interests by cultivating a network of young leaders who understand and support U.S. principles and priorities, with a focus on entrepreneurship, innovation, civic engagement, and leadership. The program equips American youth participants with language skills and cross-cultural competencies essential for success in international business, diplomacy, and security. By fostering connections among young people from the United States and key countries, the program supports the National Security Strategy’s focus on expanding alliances to secure American interests a...

By digitizing criminal court files, the project will expedite investigations and prosecutions, ensuring that individuals accused of collaborating with Foreign Terrorist Organizations (FTO)s or Transnational Criminal Organizations (TCO)s, including those who threaten U.S. Interests, are held accountable. Enhanced digital access will also strengthen collaboration between U.S. and Lebanese Law Enforcement Agencies, enabling both countries to access criminal case files in minutes rather than months. This will significantly enhance the ability of U.S. agencies to investigate and disrupt FTO and TCO activities in Lebanon, directly supporting U.S. national security objectives.

The Office of Sports Diplomacy of the U.S. Department of State’s Bureau of Educational and Cultural Affairs (ECA) invites proposals for the Sports Visitor Program. This international exchange program uses sports to advance the Administration’s foreign policy priorities, promote American leadership, and support the U.S. sports economy.  The Sports Visitor Program includes countries from all six regions of the world, as determined in consultation with the Department’s regional bureaus. The program is authorized under the Mutual Educational and Cultural Exchange Act of 1961 (Fulbright-Hays Act), which aims to increase mutual understanding and strengthen ties between the people of the United States and other nations. The Sports Visitor Program brings together American and international youth and adult coaches/chaperones for thematic, sports-based exchanges.  The target audience for this program is American and international youth (ages 15-23) and their adult coaches/chaperones.  The program is not intended for elite or professional athletes.  Through both U.S.-based and international exchanges, participants develop leadership skills, build lasting bilateral relationships, and explore the positive impact of U.S. laws – such as Title IX and the Americans with Disabilities Act (ADA) – on sports and society.  The program focuses on peer-to-peer engagement, cultural exchange, and helping youth become role models and community leaders.    Key program components include: Organizing thematic exchanges to meet program goals; Integrating with existing youth sports camps and/or creating c...

The U.S. Department of State’s Bureau of Educational and Cultural Affairs, Office of Academic Exchange Programs, Study of the U.S. Branch invites proposal submissions for one cooperative agreement to design, implement, and oversee the FY 2026 YALI Fellowship. Established in 2014 the YALI Fellowship has built and maintained a network of approximately 7,800 young African leaders across sectors critical to U.S. interests and foreign policy priorities in Sub-Saharan Africa.   The award recipient will be responsible for planning and administering all components and aspects of the YALI Fellowship including short-term academic residencies (“institutes”) on U.S. college and university campuses for approximately 550 Fellows, Professional Development Experiences (PDEs) for approximately 50 Fellows, a Reciprocal Exchange component that includes approximately 80 U.S. participants, and follow-on alumni activities. Under this award, the first group of Fellows would travel to the United States for the institutes in summer 2027. The award recipient will design the Fellowship application materials, develop an outreach and recruitment plan, receive and screen applications in collaboration with the U.S. Department of State, and oversee the final Fellow selection and placement process. The recipient will recruit, select, and oversee subawards to approximately 22 U.S. educational institutions that will each implement a six-week long institute in one of three tracks: Business and Trade, Emerging Technologies, or Governance and Security. Each institute should take place on an accredited U.S. coll...

The Office of Sports Diplomacy of the U.S. Department of State’s Bureau of Educational and Cultural Affairs (ECA) invites proposals for the Sports Envoy Program. This international exchange program uses sports to advance the Administration’s foreign policy priorities and promote American leadership and excellence. The Sports Envoy Program includes countries from all six regions of the world, as determined in consultation with the Department’s regional bureaus. The program is authorized under the Mutual Educational and Cultural Exchange Act of 1961 (Fulbright-Hays Act), which aims to increase mutual understanding and strengthen ties between the people of the United States and other nations.   The Sports Envoy Program sends current and former American professional athletes and coaches overseas on weeklong programs to promote cross-cultural understanding, engage key communities that are often difficult to reach through traditional approaches, and showcase American excellence and leadership through sport. Sports Envoys lead youth clinics and team building activities, conduct community outreach and media engagements, foster dialogue with government leaders, and meet with other U.S. embassy contacts to advance U.S. foreign policy and America First priorities.   ECA funding will support approximately 35 international exchanges for approximately 70 Envoy participants, approximately eight alumni grants, and a technology system created by the applicant.  Each Sports Envoy program typically lasts 4-7 days excluding travel, and 7-10 days including travel. Alumni grants will enable part...