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The main goal of the S-STEM program is to enable academically talented, low-income students to pursue successful careers in promising STEM fields. Ultimately, the S-STEM program seeks to increase the number of academically promising low-income students who graduate with an S-STEM eligible degree and contribute to the American innovation economy with their STEM knowledge. Recognizing that financial aid alone cannot increase retention and graduation in STEM, the program provides awards to institutions of higher education (IHEs) not only to fund scholarships, but also to adapt, implement, and study evidence-based curricular and co-curricular[a] activities that have been shown to be effective in supporting recruitment, retention, transfer (if appropriate), student success, academic/career pathways, and graduation in STEM. To be eligible, scholars must be domestic low-income students with academic ability, talent, or potential and demonstrated unmet financial need who are enrolled in an associate, baccalaureate, or graduate degree program in an S-STEM eligible discipline. Proposers must provide an analysis that articulates the characteristics and academic needs of the population of students they are trying to serve. NSF is particularly interested in supporting the attainment of degrees in fields identified as critical needs for the Nation. It is up to the proposer to make a compelling case that such a field serves a critical need in the United States. [a] an activity at a school or college pursued in addition to the normal course of study. S-STEM Eligible Degree Programs Associa...

The Coupling, Energetics, and Dynamics of Atmospheric Regions (CEDAR) program supports research to increase our understanding of the behavior of atmospheric regions from the middle atmosphere upward through the thermosphere and ionosphere into the exosphere. Projects explore coupling, energetics, chemistry, and dynamics on regional and global scales. The research topics include investigations of upper atmosphere responses due to a) processes driven by the lower atmospheric perturbations and (b) solar radiation and particle inputs from above. The activities supported by this program include observations from ground-based and space-based platforms, as well as theory and modeling of the upper atmosphere of the Earth and other planets in our solar systems. Novel approaches that include AI and ML tools and open data and open science practices are encouraged.

Expected Impact:By the end of the project: at least substantial contribution to the implementation of the targeted plan/strategy, and mechanisms established to ensure full implementation of the plan/strategy.After the project: Full implementation of the plan/strategy. In relation to those expected impacts, applicants are expected to define, calculate, explain and achieve the expected impacts as described in Award criterion ‘Impact’ of the full proposal evaluation (see Call document).Objective:Target the implementation of one or more of the following plans/strategies: Final updated National Energy and Climate Plans (NECP) and Long-Term Strategies (LTS) pursuant to Regulation on the governance of the energy union and climate action (EU) 2018/1999.National adaptation strategies and plans pursuant to Article 5 of the Regulation 2021/1119 (‘European Climate Law’), or regional adaptation strat...

Expected Impact:By the end of the project: at least substantial contribution to the implementation of the targeted plan/strategy, and mechanisms established to ensure full implementation of the plan/strategy.After the project: Full implementation of the plan/strategy. In relation to those expected impacts, applicants are expected to define, calculate, explain and achieve the expected impacts as described in Award criterion ‘Impact’ of the full proposal evaluation (see Call document).Objective:Support the full implementation of the following plans and strategies:The Prioritised Action Frameworks (PAFs) pursuant to Article 8 of Council Directive 92/43/EEC on the conservation of natural habitats and of wild fauna and flora (the Habitats Directive) and;National restoration plans pursuant to Article 14 of Regulation (EU) 2024/1991 of the European Parliament and the Council on nature restorati...

Expected Impact:Expected Impact:By the end of the project: at least substantial contribution to the implementation of the targeted plan/strategy, and mechanisms established to ensure full implementation of the plan/strategy.After the project: Full implementation of the plan/strategy. In relation to those expected impacts, applicants are expected to define, calculate, explain and achieve the expected impacts as described in Award criterion ‘Impact’ of the full proposal evaluation (see Call document).Objective:Support the full implementation of the following plans and strategies:- Circular Economy: National or Regional Circular Economy Action Plans, Strategies, Roadmaps or similar, which are officially approved, and which include specific and measurable actions, or targets, with a clear timeline and are in line with or complement the objectives of the EU Circular Economy Action Plan and, w...

This NIAMS Clinical Trial Implementation Cooperative Agreement (UG3/UH3 Clinical Trial Required) PAR, a re-issue of PAR-24-208, was re-issued as a result of the Simplifying Review of Research Project Grant Applications [link: https://grants.nih.gov/policy-and-compliance/policy-topics/peer-review/simplifying-review]. The Simplified Review changes in Section V. Application Review Information of the funding opportunity are the only changes that have been made. All other aspects of this funding opportunity remain the same.

The purpose of this Funding Opportunity Announcement (FOA) is to support high priority research at the intersection of HIV and substance use. This FOA invites innovative research projects with the potential to open new areas of HIV/AIDS research and/or lead to new avenues for prevention, treatment and cure of HIV among people who use drugs (PWUD). Applications submitted under this FOA are required to have a detailed research plan, preliminary data, and a clear description of the nexus with substance use. This FOA is open to both individual researchers and research teams and includes all areas of research from basic science to clinical and implementation research. All studies must focus on NIH HIV/AIDS Research Priorities: NOT-OD-20-018: UPDATE: NIH HIV/AIDS Research Priorities and Guidelines for Determining HIV/AIDS Funding.

The purpose of this Notice of Funding Opportunity (NOFO) is to support investigators who have the interest and capability to join efforts for the discovery of in vivo chemical probes for novel brain targets. It is expected that applicants will have, in hand, the starting compounds (validated hits) for chemical optimization and bioassays for testing new analog compounds.Through this NOFO, NIH wishes to stimulate research in:Discovery and development of novel, small molecules for their potential use in understanding biological processes relevant to the missions of National Institute of Mental Health (NIMH), National Institute on Drug Abuse (NIDA), National Eye Institute (NEI), and/or National Institute on Aging (NIA) andDiscovery and/or validation of novel, biological targets that will inform studies of brain disease mechanisms.Emphasis will be placed on projects that provide new insight into important disease-related biological targets and biological processes.

The purpose of this Funding Opportunity Announcement (FOA) is to support high priority research at the intersection of HIV and substance use. This FOA invites innovative research projects with the potential to open new areas of HIV/AIDS research and/or lead to new avenues for prevention, treatment and cure of HIV among people who use drugs (PWUD). Applications submitted under this FOA are required to have a detailed research plan, preliminary data, and a clear description of the nexus with substance use. This FOA is open to both individual researchers and research teams and includes all areas of research from basic science to clinical and implementation research. All studies must focus on NIH HIV/AIDS Research Priorities: NOT-OD-20-018: UPDATE: NIH HIV/AIDS Research Priorities and Guidelines for Determining HIV/AIDS Funding.

The goal of this program is to support collaborative translational research projects aligned with NIH efforts to enhance the translation of basic biological discoveries into clinical applications that improve health. It encourages high quality science demonstrating the potential to result in understanding an important disease process or lead to new therapeutic interventions, diagnostics, or prevention strategies within the research interests and priorities of the participating NIH Institutes/Centers (ICs).Specifically, the program seeks to broaden and strengthen translational research collaborations between basic and clinical researchers both within and outside NIH to accelerate and enhance translational science by promoting partnerships between NIH intramural investigators (e.g., those conducting research within the labs and clinics of the NIH) and extramural investigators (e.g., those conducting research in labs outside the NIH), and by providing support for extramural investigators to take advantage of the unique research opportunities available at the NIH Clinical Center by conducting clinical research projects in collaboration with NIH intramural investigators.

This notice of funding opportunity (NOFO) encourages formative research, intervention development, and pilot-testing of interventions. Primary scientific areas of focus include the feasibility, tolerability, acceptability and safety of novel or adapted interventions that target HIV prevention, treatment or services research for people who use drugs. For the purposes of this NOFO, "intervention" may include behavioral, social, or structural approaches, as well as combination biomedical and behavioral approaches that prevent the acquisition and transmission of HIV infection, or improve clinical outcomes for persons living with HIV.

Broad Agency Announcement for Air Delivered Effects - Amendment 5

The Innovations in Graduate Education (IGE) Program is designed to encourage development and implementation of bold, new, and potentially transformative approaches to STEM graduate education training. The program seeks proposals that a) explore ways forgraduate students in STEM master’s and doctoral degree programs to develop the skills, knowledge, and competencies needed to pursue a range of STEM careers, or b) support research on the graduate education system and outcomes of systemic interventions and policies. IGE projects are intendedto generate the knowledge required for the customization, implementation, and broader adoption of potentially transformative approaches to graduate education. The program supports piloting, testing, and validating novel models or activities and examining systemic innovations with high potential to enrich and extend the knowledge base on effective graduate education approaches. The program addresses both workforce development, emphasizing broad participation, and institutional capacity-building needs in graduate education. Strategic collaborations with the private sector, non-governmental organizations (NGOs), government agencies, national laboratories, field stations, teaching and learning centers, informal science organizations, and academic partners are encouraged.

The far-reaching impact and rate of innovation in the computer and information science and engineering fields has been remarkable, generating economic prosperity and enhancing the quality of life for people throughout the world. More than a decade ago, the National Science Foundation’s (NSF) Directorate for Computer and Information Science and Engineering (CISE) established the Expeditions in Computing (Expeditions) program to build on past successes and provide the CISE research and education community with the opportunity to pursue ambitious, fundamental research agendas that promise to define the future of computing and information. In planning Expeditions projects, investigators are strongly encouraged to come together within or across departments or institutions to combine their creative talents in the identification of compelling, transformative research agendas that look ahead by at least a decade and promise disruptive innovations in computer and information science and engineering for many years to come. Now funded at levels up to $15,000,000 for seven years, Expeditions projects represent some of the largest single investments currently made by the CISE directorate. Together with the Science and Technology Centers and the National Artificial Intelligence Research Institutes that CISE supports, Expeditions projects form the centerpiece of the directorate's center-scale award portfolio. With awards funded at levels that promote the formation of large research teams, CISE recognizes that concurrent research advances in multiple fields or sub-fields are often necessary to....

The U.S. Military Academy at West Point's mission is "to educate, train, and inspire the Corps of Cadets so that each graduate is a commissioned leader of character committed to the values of Duty, Honor, Country and prepared for a career of professional excellence and service to the Nation as an officer in the United States Army." The United States Military Academy is located at West Point, New York. USMA executes research to enhance the education of cadets, develop the faculty professionally, and address important issues facing the Army and the Nation. In addition, the Academy conducts research and analysis in emerging fields that may realize novel or vastly improved Army capabilities. At West Point, research is organized and administered through centers and institutes, most of which reside within academic departments. These centers and institutes, affiliated with each other through the Academy Research Council (ARC), coordinated and supported by the Academic Research Division (ARD), provide the infrastructure necessary to tackle the nation’s and the world’s most challenging problems. Our research centers and institutes bring context to the classroom, are central to our vibrant and pioneering faculty, and are one way West Point connects to the Army and to the Nation. Our students are driven, our faculty is world-class, and through our centers, scholars and scientists thrive and produce their best work. Cadets regularly win Best Paper Awards at national and international graduate-level conferences, our faculty hold fellowships and chairmanships in their discipline's nation...

The purpose of this Notice of Funding Opportunity (NOFO) is to advance efforts for a nationally integrated animal food safety system providing state animal food regulatory programs the ability to achieve full implementation of the Animal Food Regulatory Program Standards (AFRPS) within 5 years and to maintain full implementation. This NOFO will also fund optional projects for state animal food regulatory programs to:Advance food safety and protect public health by strengthening partnerships with the FDA and other state animal food regulatory partners through sharing, collaboration, coordination, and leveraging each other’s expertise, work, data, and enforcement actions.Develop and standardize processes, procedures, systems, and other methods to integrate federal and state animal food regulatory work resulting in mutual reliance.Specific outcomes may include, but are not limited to:State animal food regulatory programs will achieve and maintain implementation of the AFRPS, which is recognized as a critical element to creating a national, fully integrated food safety system.Operational use of standardized animal food regulatory systems developed by state programs to compel federal reliance on state regulatory work and resources and reciprocal state reliance on federal work and resources, resulting in mutual reliance.This project will strengthen and improve FDA efforts to build an integrated food safety system by building high quality state animal food regulatory programs that can promote regulatory compliance and prevent foodborne illnesses.

This Funding Opportunity Announcement (FOA) issued by the Food and Drug Administration (FDA), Center for Veterinary Medicine (CVM), builds upon the National Antimicrobial Resistance Monitoring System (NARMS) which was initiated in 1996 as one of the key activities in a national action plan to combat antibiotic resistance threats. The purpose of this FOA is to protect and promote public health by enhancing, strengthening, and sustaining antibiotic resistance surveillance in retail food specimens within the NARMS program. The NARMS cooperative agreement is intended to improve the detection of antibiotic resistance among bacteria in food commodities, as well as expand to new sites to expand the scope of sampling. Measurable outcomes of the program will be in alignment with the NARMS Objectives.

The National Quantum Initiative (NQI) Act1aims to ensure the continuing leadership of the United States (U.S.) in quantum information science and technology. In conformance with the NQI goals, an argument2-5was set forth for a renewed emphasis on identifying and fostering early adoption of quantum technologies to transform the field of Quantum Information Science and Engineering (QISE) and to accelerate broader impacts on society. A systematic approach to maturing quantum technology platforms by integrating end-users and potential customers from other fields of science and engineering and other sectors of the economy into cycles of research, development, and demonstration should lower the barriers for end-users to pioneer new applications. NSF support for use-inspired and translational research in QISE, combined with continued strong support of the underlying foundational research, is anticipated to accelerate development of a market for quantum technologies. With this program solicitation, the Foundation is taking the next step in implementing the National Quantum Virtual Laboratory (NQVL) concept as an overarching shared infrastructure designed to facilitate the translation from basic science and engineering to the resultant technology, while at the same time emphasizing and advancing its scientific and technical value. The NQVL aims to develop and utilize use-inspired and application-oriented quantum technologies. In the process, NQVL researchers will explore quantum frontiers6, foster the development of QISE education and workforce development strategies, engage in outr...

The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH. The overarching goal of this R25 program is to support educational activities that complement and/or enhance the training of a workforce to meet the nations biomedical, behavioral and clinical research needs. To accomplish the stated over-arching goal, this FOA will support creative educational activities with a primary focus on: Courses for Skills Development

The Established Program to Stimulate Competitive Research is designed to fulfill the mandate of the National Science Foundation (NSF) to promote scientific progress nationwide. NSF EPSCoR facilitates the establishment of partnerships among academic institutions, government, industry, and non-profit sectors that are designed to promote sustainable improvements in a jurisdiction's research infrastructure, Research and Development (R&D) capacity, and R&D competitiveness of EPSCoR-eligible jurisdictions (i.e., states, territories, and commonwealths). Eligibility to participate in the EPSCoR funding opportunities, including the EPSCoR RII: EPSCoR Research Fellows program, is described on theNSF EPSCoR website. EPSCoR RII: EPSCoR Research Fellows directly aligns with the NSF EPSCoR strategic goal of establishing sustainable Science, Technology, Engineering, and Mathematics (STEM) professional development pathways that advance workforce development and effects engagement in STEM at national and global levels. EPSCoR RII: EPSCoR Research Fellows provides awards to build researchcapacityin institutions and transform the career trajectories of investigators and further develop their individual research potential through collaborations with investigators from the nation’s premier private, governmental, or academic research institutions and/or centers. The fellowship provides opportunities to establish strong collaborations through extended or periodic collaborative visits to a selected host site.Through collaborative research activities with the host site, Fellows will be able to lear...

The FAIROS Program seeks to support a broad range of transformative open science activities including but not limited to i.) Research, education, and socio-technical cyberinfrastructure development capacities that advance sustainable multi-disciplinary findable, accessible, interoperable, reusable (FAIR) research data management (RDM) and open science capabilities, ii.) Piloting new models of scientific communication and publication that improve efficiency and accessibility, iii.) Developing FAIROS data portals, research data commons, RDM as a national service, and iv.) Lowering barriers to accessing, curating, integrating, linking, managing, sharing, and storing data across many disciplinary domains, irrespective of data size. The program supports innovation across the cyberinfrastructure (CI) ecosystem to address accessibility, data curation, research data management, discoverability, reliability, reproducibility, preservation, sustainability, and utility of research products, including data software, and code, developed as part of funded projects. FAIROS proposals must select one of two tracks to focus on, either: 1) Disciplinary Improvements to targeted scientific communities, or 2) Cross-Cutting Improvements that apply to many or most scientific disciplines. In the case of proposals focused on Disciplinary Improvements, it is strongly recommended that prospective PIs contact a program officer from the list of Cognizant Program Officers in the directorate closest to the major disciplinary impact of the proposed work to ascertain that the scientific focus and budget of t...

NLM wishes to accelerate access to, and availability of, secure, complete datasets and computational models that can serve as the basis for transformative biomedical discoveries. Innovative at-scale computational approaches that increase the speed and scope of curation processes are needed for data mining and knowledge discovery from growing quantities of biomedical data being produced from ongoing data science advances.

The National Institutes of Health (NIH) hereby notify the applicant community that funds may be available for applications based on a presidentially declared disaster under the Stafford Act, a public health emergency declared by the Secretary, HHS, or other local, regional or national disaster. Applications in response to Emergency Notices of Special Interest (NOSIs) will be routed directly to the NIH awarding component signed on to the Emergency NOSI. Only applications submitted in response to an Emergency NOSI published by an IC will be allowed to apply to this NOFO.

This Notice of Funding Opportunity Announcement (NOFO) invites grant applications for Environmental Health Sciences Core Centers (EHSCC). As intellectual hubs for environmental health science research, the EHSCC's are expected to be the thought leaders for the field and advance the goals of the 2025-2029 NIEHS Strategic Plan (http://www.niehs.nih.gov/about/strategicplan/). The Core Centers provide critical research infrastructure, shared facilities, services and/or resources, to groups of investigators conducting environmental health sciences research. An EHSCC enables researchers to conduct their independently-funded individual and/or collaborative research projects more efficiently and/or more effectively. The overall goal of an EHSCC is to identify and capitalize on emerging issues that advance improving the understanding of the relationships among environmental exposures, human biology, and disease. The EHSCC supports community engagement and translational research as key approaches to improving public health.

The purpose of the NHLBI Outstanding Investigator Award (OIA) is to promote scientific productivity and innovation by providing long-term support and increased flexibility to experienced Program Directors/Principal Investigators (PDs/PIs) who are currently PDs/PIs on at least two NHLBI R01-equivalent awards and whose outstanding record of research demonstrates their ability to make major contributions to heart, lung, blood and sleep (HLBS) research. The OIA is intended to support a research program, rather than a research project, by providing the primary and most likely sole source of NHLBI funding on individual grant awards. The OIA will support the research program of NHLBI-funded investigators for up to seven years. The OIA will provide investigators increased freedom to conduct research that breaks new ground or extends previous discoveries in new directions. It will also allow PDs/PIs to take greater risks and to pursue research that requires a longer timeframe. Research supported by the OIA must be within the scope of the NHLBI mission (https://www.nhlbi.nih.gov/about/mission-statement). It is anticipated that the OIA will: Provide a stable funding environment, thereby improving productivity and facilitating nimble, ambitious, creative research; Accelerate scientific innovation by enabling flexibility in pursuing new research directions as they arise, since PDs/PIs will not be bound to specific aims proposed in advance of the studies; Reduce the time researchers spend writing grant applications and managing multiple grant awards, thereby allowing more time to be devo...