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The purpose of the NIDA Animal Genetics Program is to identify genetic, genomic, and molecular (epi)genetic variants that underlie: 1. Phenotypes associated with addictive behaviors and/or vulnerability to distinct stages along the substance use disorders (SUD) trajectory (e.g. initial/acute use, escalation of use, acquisition of tolerance, dependence, uncontrolled use, abstinence and relapse or recovery); 2. Behaviors associated with SUD (e.g. impulsivity, novelty seeking, delayed discounting, and other genetically-associated phenotypes); and 3. Comorbidities that demonstrate genetic correlations with phenotypes and behaviors linked with SUD (e.g. anxiety, stress, poor maternal care, social defeat, and other paradigms). Applications may examine any type of genomic variant, including single nucleotide variants (SNVs), indels, large and small structural variants, and all types of mobile DNA. NIDA encourages applications that take genomics, multi-omics, and/or data-based approaches that integrate multi-level omics data, delineate gene networks, and/or uncover the function of known or newly discovered genetic or epigenetic variants. Other areas of interest include genomics analysis at the circuit level and the application of neuroscience to genomics studies. NIDA expects these studies to uncover novel mechanisms that contribute to various stages across the SUD trajectory and inform future studies about potential targets and therapeutic strategies for addiction.

Invasive surgical procedures in humans offer the unique opportunity to intracranially record and stimulate neuronal activity within precisely localized brain structures, enabling high-impact human neuroscience investigations. This NOFO seeks exploratory research projects, from newly formed or established multi-disciplinary teams, to understand how dynamic activity of single cells and ensembles of neurons in spatially organized networks gives rise to the internal states we experience as sensations, perceptions, emotions, thoughts, and memories, and to observable motor and social behaviors. The research should be proposed as exploratory research and planning activities to establish feasibility and early-stage development that, if successful, would support, enable, and/or lay the groundwork for a potential, subsequent research project grant applications using invasive neural recording and stimulation technologies in the human brain. Projects should maximize opportunities to conduct innovative in vivo human neuroscience research made available by direct access to the brain from invasive surgical procedures. Projects should employ approaches guided by specified theoretical constructs and by quantitative, mechanistic models where appropriate. Recipients will join a consortium working group, coordinated by the NIH, to identify consensus standards of practice, including neuroethical considerations, to collect and provide data for ancillary studies, and to aggregate and standardize data for dissemination among the wider scientific community.

The Department of State invites eligible applicants to advance the America First Global Health Strategy, which aims to save lives, strengthen health systems, enhance efficiency, foster self-reliance, and ensure U.S. investments benefit American safety, strength, and prosperity. This Annual Program Statement (APS) establishes a supplemental framework through which the Department of State may identify and support projects that complement, extend, and/or fill identified gaps in the implementation of these bilateral MOUs. Through specific Addenda, the Department will signal priorities and needs. This APS provides the standard application instructions for the submission of all Statements of Interest (SOIs) to these specific Addenda. GHSD will collaborate with Embassies and other Department of State Bureaus and Offices to post specific funding opportunities through Addenda to this APS that address health challenges and priorities of importance.

The Department of State invites eligible applicants to advance the America First Global Health Strategy, which aims to save lives, strengthen health systems, enhance efficiency, foster self-reliance, and ensure U.S. investments benefit American safety, strength, and prosperity. This Annual Program Statement (APS) establishes a supplemental framework through which the Department of State may identify and support projects that complement, extend, and/or fill identified gaps in the implementation of these bilateral MOUs. Through specific Addenda, the Department will signal priorities and needs. This APS provides the standard application instructions for the submission of all Statements of Interest (SOIs) to these specific Addenda. GHSD will collaborate with Embassies and other Department of State Bureaus and Offices to post specific funding opportunities through Addenda to this APS that address health challenges and priorities of importance.

The Department of State invites eligible applicants to advance the America First Global Health Strategy, which aims to save lives, strengthen health systems, enhance efficiency, foster self-reliance, and ensure U.S. investments benefit American safety, strength, and prosperity. This Annual Program Statement (APS) establishes a supplemental framework through which the Department of State may identify and support projects that complement, extend, and/or fill identified gaps in the implementation of these bilateral MOUs. Through specific Addenda, the Department will signal priorities and needs. This APS provides the standard application instructions for the submission of all Statements of Interest (SOIs) to these specific Addenda. GHSD will collaborate with Embassies and other Department of State Bureaus and Offices to post specific funding opportunities through Addenda to this APS that address health challenges and priorities of importance.

The Department of State invites eligible applicants to advance the America First Global Health Strategy, which aims to save lives, strengthen health systems, enhance efficiency, foster self-reliance, and ensure U.S. investments benefit American safety, strength, and prosperity. This Annual Program Statement (APS) establishes a supplemental framework through which the Department of State may identify and support projects that complement, extend, and/or fill identified gaps in the implementation of these bilateral MOUs. Through specific Addenda, the Department will signal priorities and needs. This APS provides the standard application instructions for the submission of all Statements of Interest (SOIs) to these specific Addenda. GHSD will collaborate with Embassies and other Department of State Bureaus and Offices to post specific funding opportunities through Addenda to this APS that address health challenges and priorities of importance.

The Oceanographic Technology and Interdisciplinary Coordination (OTIC) Program supports a broad range of research and technology development activities. Unsolicited proposals are accepted for instrumentation development that has broad applicability to ocean science research projects and that enhance observational, experimental or analytical capabilities of the ocean science research community. Specific announcements for funding opportunities are made for additional projects involving Improvements in Facilities, Communications, and Equipment at Biological Field Stations and Marine Laboratories (FSML) and the National Ocean Partnership Program.

Expected Impact:Projects are expected to deliver results aligned with the expected results set out in this call topic and to evidence their contribution through dedicated KPIs defined in the proposal. Expected results include: • demonstrable and sustainable increase in production capacity in UA for the targeted (counter-)UxS-related production lines; • measurable reduction of production lead time from order/production decision to delivery in UA; • improved timely availability and supply of defence products in UA, including increased delivery reliability and readiness of production lines; • effective cross-border cooperation between UA and EU that enables production ramp-up, integration, qualification and sustainment; • strengthened Ukrainian industrial base, and, where applicable, operationalised MaaS and dual-use heavy industry conversion pathways for surge. Proposals shall define, base...

Expected Impact:The results of the activities should contribute to support common procurement, leading to strengthening the cooperation among Member States and associated countries, as well as to greater interoperability. Furthermore, they should contribute to should contribute to the development and reinforcement of C5ISR and space-related products of the participants.Objective:The results of the activities should contribute to support common procurement, leading to strengthening the cooperation among Member States and associated countries, as well as to greater interoperability. Furthermore, they should contribute to the development and the procurement of common platforms and subsystems.Scope:Common procurement actions under this topic shall consist of activities related to the cooperation of legal entities in the procurement of C5ISR or other space-related defence products and systems...

Expected Impact:The results of the activities should contribute to support common procurement, leading to strengthening the cooperation among Member States and associated countries, as well as to greater interoperability. Furthermore, they should contribute to the development and reinforcement of air and missile defence capabilities of the participants.Objective:This topic aims at actions supporting the common procurement of integrated, multilayered, air and missile defence, or parts thereof including sensors (e.g. radars), kinetic or non-kinetic effectors, command and control, that protects against the full spectrum of air threats (cruise missiles, ballistic and hypersonic missiles, aircraft and UAS) from medium to long range, high and terminal high altitude, including endo-atmospheric interceptor. This topic does not cover very short to short range air defence systems against low altit...

Expected Impact:Projects are expected to deliver results aligned with the expected results set out in this call topic and to evidence their contribution through dedicated KPIs defined in the proposal. Expected results include: • tangible capacity increases in EU-based production enabling the ramp-up of the targeted platforms or end-products, with demonstrated contribution to competitiveness; • improved resilience & geographical distribution of supply and industrial capability, reducing single points of failure across forging/machining, key sub-systems, composites and assembly/integration; • strengthened availability and security of supply of the targeted platforms or end-products with identified risks and exposure to the risk of materialisation of conventional military threats; • and measurable lead-time reductions, establishment or availability of reserved capacity where applicable, and...

Expected Impact:Projects are expected to deliver results aligned with the expected results set out in this call topic and to evidence their contribution through dedicated KPIs defined in the proposal. Expected results include: • tangible capacity increases in EU-based production of the targeted electronic components, with demonstrated contribution to competitiveness; • improved resilience & geographical distribution of supply, reducing single points of failure; • strengthened availability and security of supply for priority defence product production lines, commensurate with identified risks and exposure to the risk of • materialisation of conventional military threats; • and measurable lead-time reductions, establishment or availability of reserved capacity where applicable, and workforce trained to operate and sustain the reinforced production lines. Proposals shall define, baseline an...

Expected Impact:The results of the activities should contribute to support common procurement, leading to strengthening the cooperation among Member States and associated countries, as well as to greater interoperability. Furthermore, they should contribute to the development and the procurement of common platforms and subsystems.Objective:This topic aims to support the common procurement of a wide range of capabilities or systems of ground and naval platforms or parts thereof, including but not limited to artillery systems, (counter)-mobility platforms, tanks or other armoured vehicles, support vehicles, combat platforms, soldier systems, surface and underwater naval platforms or their sub-systems.Scope:Common procurement actions under this topic shall consist of activities related to the cooperation of legal entities in the procurement of ground, naval platforms and systems, at any poi...

Objective:This topic targets projects linked to a framework loan to address serious social, economic and environmental challenges deriving from the transition towards the EU’s 2030 climate and energy targets and the EU’s 2050 objective of climate neutrality, for the benefit of the EU territories identified in the Territorial Just Transition Plans.- The projects must be linked to an EIB framework loan. Framework loans by other banks or EIB financial intermediaries (including EIB Intermediated Framework Loans or Multi-Beneficiary Intermediated Loans) cannot benefit from PSLF funding under this topic.Scope:Projects related to a wide range of sustainable investments may be funded, such as:investments in renewable energy and green and sustainable mobility, including the promotion of green hydrogenefficient district heating networkspublic researchdigitalisationenvironmental infrastructure for...

Objective:This topic targets projects addressing serious social, economic and environmental challenges deriving from the transition towards the EU’s 2030 climate and energy targets and the EU’s 2050 objective of climate neutrality, for the benefit of the EU territories identified in the Territorial Just Transition Plans.The projects must also qualify for a loan by the EIB (or one of its financial intermediaries).Scope:Projects related to a wide range of sustainable investments may be funded, such as:investments in renewable energy and green and sustainable mobility, including the promotion of green hydrogenefficient district heating networkspublic researchdigitalisationenvironmental infrastructure for smart waste and water managementsustainable energy, energy efficiency and integration measures, including renovations and conversions of buildingsurban renewal and regenerationthe transitio...

This Funding Opportunity Announcement is intended to identify and support research projects by exceptionally promising Early Stage Investigators with a long-term career interest in pursuing innovative research in genomics. This opportunity is open to research in all areas relevant to the mission of NHGRI, including genomic sciences, genomic medicine, genomic data science, and ethical, legal, and social implications of genomics.

The MCA program offers an opportunity for scientists and engineers at the mid-career stage (see restrictions under Additional Eligibility Information) to substantively enhance and advance theirresearch program and career trajectory. Mid-career scientists are at a critical career transition stage where they need to advance their research programs to ensure long-term productivity and creativity but are often constrained by service, teaching, or other activities that limit the amount of time devoted to research. The MCA program provides protected time, resources, and the means to gain new skills through synergistic and mutually beneficial partnerships, typically at an institution other than the candidate's home institution. Partners from outside the Principal Investigator's (PI) own subdiscipline or discipline are encouraged, but not required, to enhance interdisciplinary networking and convergence across science and engineering fields. Research projects that envision new insights on existing problems or identify new problems made accessible with cutting-edge methodology or expertise from other fields are encouraged. A key component of a successful MCA will be the demonstration that the PI's currentresearchprogram could substantively benefit from the protected time, mentored partnership(s), and resources provided through this program, such thatthere is a substantial enhancement to the PI's research and career trajectory, enabling scientific and academic advancementnot likely without this support. The MCA is the only cross-directorate NSF program specifically aimed at providing...

The purpose of this Program Announcement with Special Receipt, Referral, and/or Review Considerations (PAR) is to solicit applications to access stored blood plasma, blood serum, and extracted DNA from the All of Us Research Program supported Biobank to advance the program's mission of accelerating health research and medical breakthroughs, enabling individualized prevention, treatment, and care for all of us.All of Us partnered research studies are collaborative initiatives funded by a study sponsor external to All of Us to collect and add new data to the All of Us Researcher Workbench in accordance with All of Us" best practices. All of Us partnered research studies are open to the broad scientific community and require investigators to apply for and receive an X01 award under this announcement.This will enable longitudinal follow‐up and repeat sampling, and provide multiomic data (genomics, proteomics, metabolomics, and other high‐dimensional molecular profiles), integrated clinical, environmental, and life‐course data, infrastructure designed to support future clinical‐trial recruitment, and public‐private partnership pathways.This opportunity will enable researchers to conduct assays to evaluate associations between newly collected and existing All of Us data and add new data to the All of Us dataset for broad use by the research community. High-priority areas for biospecimen analyses may include, but are not limited to, large scale projects that propose integrated multiomics analyses, early disease detection, biomarker discovery or validation, novel risk models for in...

The main goal of the S-STEM program is to enable academically talented, low-income students to pursue successful careers in promising STEM fields. Ultimately, the S-STEM program seeks to increase the number of academically promising low-income students who graduate with an S-STEM eligible degree and contribute to the American innovation economy with their STEM knowledge. Recognizing that financial aid alone cannot increase retention and graduation in STEM, the program provides awards to institutions of higher education (IHEs) not only to fund scholarships, but also to adapt, implement, and study evidence-based curricular and co-curricular[a] activities that have been shown to be effective in supporting recruitment, retention, transfer (if appropriate), student success, academic/career pathways, and graduation in STEM. To be eligible, scholars must be domestic low-income students with academic ability, talent, or potential and demonstrated unmet financial need who are enrolled in an associate, baccalaureate, or graduate degree program in an S-STEM eligible discipline. Proposers must provide an analysis that articulates the characteristics and academic needs of the population of students they are trying to serve. NSF is particularly interested in supporting the attainment of degrees in fields identified as critical needs for the Nation. It is up to the proposer to make a compelling case that such a field serves a critical need in the United States. [a] an activity at a school or college pursued in addition to the normal course of study. S-STEM Eligible Degree Programs Associa...

The Coupling, Energetics, and Dynamics of Atmospheric Regions (CEDAR) program supports research to increase our understanding of the behavior of atmospheric regions from the middle atmosphere upward through the thermosphere and ionosphere into the exosphere. Projects explore coupling, energetics, chemistry, and dynamics on regional and global scales. The research topics include investigations of upper atmosphere responses due to a) processes driven by the lower atmospheric perturbations and (b) solar radiation and particle inputs from above. The activities supported by this program include observations from ground-based and space-based platforms, as well as theory and modeling of the upper atmosphere of the Earth and other planets in our solar systems. Novel approaches that include AI and ML tools and open data and open science practices are encouraged.

This NIAMS Clinical Trial Implementation Cooperative Agreement (UG3/UH3 Clinical Trial Required) PAR, a re-issue of PAR-24-208, was re-issued as a result of the Simplifying Review of Research Project Grant Applications [link: https://grants.nih.gov/policy-and-compliance/policy-topics/peer-review/simplifying-review]. The Simplified Review changes in Section V. Application Review Information of the funding opportunity are the only changes that have been made. All other aspects of this funding opportunity remain the same.

Expected Impact:Expected Impact:By the end of the project: at least substantial contribution to the implementation of the targeted plan/strategy, and mechanisms established to ensure full implementation of the plan/strategy.After the project: Full implementation of the plan/strategy. In relation to those expected impacts, applicants are expected to define, calculate, explain and achieve the expected impacts as described in Award criterion ‘Impact’ of the full proposal evaluation (see Call document).Objective:Support the full implementation of the following plans and strategies:- Circular Economy: National or Regional Circular Economy Action Plans, Strategies, Roadmaps or similar, which are officially approved, and which include specific and measurable actions, or targets, with a clear timeline and are in line with or complement the objectives of the EU Circular Economy Action Plan and, w...

Expected Impact:By the end of the project: at least substantial contribution to the implementation of the targeted plan/strategy, and mechanisms established to ensure full implementation of the plan/strategy.After the project: Full implementation of the plan/strategy. In relation to those expected impacts, applicants are expected to define, calculate, explain and achieve the expected impacts as described in Award criterion ‘Impact’ of the full proposal evaluation (see Call document).Objective:Support the full implementation of the following plans and strategies:The Prioritised Action Frameworks (PAFs) pursuant to Article 8 of Council Directive 92/43/EEC on the conservation of natural habitats and of wild fauna and flora (the Habitats Directive) and;National restoration plans pursuant to Article 14 of Regulation (EU) 2024/1991 of the European Parliament and the Council on nature restorati...

Expected Impact:By the end of the project: at least substantial contribution to the implementation of the targeted plan/strategy, and mechanisms established to ensure full implementation of the plan/strategy.After the project: Full implementation of the plan/strategy. In relation to those expected impacts, applicants are expected to define, calculate, explain and achieve the expected impacts as described in Award criterion ‘Impact’ of the full proposal evaluation (see Call document).Objective:Target the implementation of one or more of the following plans/strategies: Final updated National Energy and Climate Plans (NECP) and Long-Term Strategies (LTS) pursuant to Regulation on the governance of the energy union and climate action (EU) 2018/1999.National adaptation strategies and plans pursuant to Article 5 of the Regulation 2021/1119 (‘European Climate Law’), or regional adaptation strat...

The purpose of this Funding Opportunity Announcement (FOA) is to support high priority research at the intersection of HIV and substance use. This FOA invites innovative research projects with the potential to open new areas of HIV/AIDS research and/or lead to new avenues for prevention, treatment and cure of HIV among people who use drugs (PWUD). Applications submitted under this FOA are required to have a detailed research plan, preliminary data, and a clear description of the nexus with substance use. This FOA is open to both individual researchers and research teams and includes all areas of research from basic science to clinical and implementation research. All studies must focus on NIH HIV/AIDS Research Priorities: NOT-OD-20-018: UPDATE: NIH HIV/AIDS Research Priorities and Guidelines for Determining HIV/AIDS Funding.