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Society relies on chemical processes to turn raw materials into useful products. The Chemical Process Systems (CPS) program invests in fundamental research on chemical and biochemical processes to make them more efficient, sustainable, and resilient. New CPS technologies for manufacturing, biotechnology, critical minerals, energy, food, and other national priorities will help make the U.S. more competitive and secure. Research supported by the CPS program covers the full breadth of chemical and biochemical process innovation. It spans reaction engineering and molecular thermodynamics; reactor design; catalysis; electrochemical systems; separations; and process design. The program encourages proposals that connect the molecular scale to process and plant scales. The CPS program explores active-site structure and function, reaction mechanisms, in situ and operando characterization, durability, and device-level integration. Microreactors, membrane and catalytic reactors, atmospheric plasmas, and other novel configurations are of interest. The program supports research in catalysis and electrochemical systems to produce, use, and store energy, to reduce waste, to process polymers, and to synthesize fuels and chemicals. This includes process and materials innovation to support the nuclear fuel cycle. The CPS program also targets chemical and biological separations that are efficient and scalable. Research includes the design of membranes, sorbents, and specialized interfaces. Advances can be used in gas separations, the recovery of critical minerals, bioprocessing, and protein a...

The Engineering Biological and Biomedical Systems (EBBS) program expands our understanding of biological and physiological systems, and it helps improve human health. For U.S. leadership in biotechnology, the engineering of biology is required at every scale. Engineering is needed for sensing biomarkers to making proteins to restoring functions of the body. In EBBS, fundamental mechanistic insights are combined with experimental and computational techniques. This approach helps develop platforms, devices, organisms, tissues, and processes that bring new understanding and control of biological functions. EBBS supports studies of mechanisms that drive the behavior of microbial populations and cells, and of therapeutic cells and tissues. This includes discovering the underlying engineering principles that are needed to capture the responses of biological systems and bioreactors. It also includes the creation of novel biosensing platforms and new optical imaging and modulation strategies. Research that enables the design of biological systems to sense and respond to novel stimuli is welcome. Similarly, projects leading to insight into tissue changes or injury, and to systems that imitate or restore the functions of tissues or organs are encouraged. Projects that advance rehabilitation engineering through new theories and approaches are supported by the EBBS program. Fundamental engineering research driven by the needs of persons with disabilities is encouraged. The EBBS program expands what is possible in biomanufacturing; research may advance biotechnology and/or health. EBBS....

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The Professional Formation of Engineers (PFE) initiative integrates engineering research and education to improve and expand the nation’s engineering workforce. PFE is defined as the formal and informal processes and value systems by which people become engineers. The goal of PFE is to create an ethical engineering workforce with a global outlook and the ability to adapt to the rapidly evolving technical environment. This will help build a future engineering workforce with the skills to compete in the global marketplace, support emerging technologies, and grow U.S. industry. PFE supports projects in the ENGINEER program relating to future and current engineers’ training and education in many contexts, including formal classrooms, informal maker spaces, clubs and co-curricular activities, and workplaces. Such training encompasses cooperative education and internships, community-based experiences, and research labs. It also involves many scales of analysis, from mentor/mentee relationships to large-scale online learning and professional development experiences. Engineers must develop and maintain these learning opportunities with clear pathways to and through the profession. Such pathways include formal and informal education, apprenticeships, credentialing, and licensure, and consider relationships with other professionals, technical workers, and community members. Finally, such opportunities include transitions across and within academia and industry. To understand and improve this system requires expertise in both engineering and the social sciences.

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